NR 565 PHARMACOLOGY WEEK 4 QUESTIONS WITH
ACCURATE ANSWERS
ACP recommendations for Gout correct answer 1. Corticosteroids, NSAIDs, or
colchicine for acute gout
2. Low-dose colchicine for acute gout
3. Avoid long-term urate-lowering therapy after 1st gout attack or in patients with
infrequent attacks
4. Discuss benefits, harms, cost, and preferences before initiating urate-lowering
therapy
Adverse reactions: Colchicine correct answer Rhabdomyolysis
Increased risk in patients who take statins
Discuss potential risk of muscle injury
Allopurinol and Warfarin correct answer Allopurinol may delay metabolism of
warfarin
Warfarin dose should be decreased when allopurinol is added
Allopurinol hypersensitivity syndrome correct answer Severe, can be life
threatening
Rash, fever, liver dysfunction, renal dysfunction
Stop allopurinol, seek medical attention
Don't take antihistamines
Baseline data: Bisphosphonates correct answer Axial DXA + height
Serum ca++ and vit. d
, Creatinine level/renal function
Pregnancy test
Baseline data: Denosumab correct answer DXA + height
Oral exam
Baseline ca++ and vit. d
Pregnancy test
Baseline data: Raloxifene correct answer DXA + height
Baseline ca++ and vit. d
Mammogram
Pregnancy test
Baseline diagnostic data: Conventional DMARDs correct answer ALT, AST, serum
creatinine
Baseline diagnostic data: Hydroxychloroquine correct answer Ophthalmic exam,
cardiac exam w/ ECG
Baseline diagnostic data: Leflunomide correct answer Chest x-ray, BP + pulmonary
status
Baseline diagnostic data: Methotrexate correct answer Chest x-ray, pulmonary +
GI status
ACCURATE ANSWERS
ACP recommendations for Gout correct answer 1. Corticosteroids, NSAIDs, or
colchicine for acute gout
2. Low-dose colchicine for acute gout
3. Avoid long-term urate-lowering therapy after 1st gout attack or in patients with
infrequent attacks
4. Discuss benefits, harms, cost, and preferences before initiating urate-lowering
therapy
Adverse reactions: Colchicine correct answer Rhabdomyolysis
Increased risk in patients who take statins
Discuss potential risk of muscle injury
Allopurinol and Warfarin correct answer Allopurinol may delay metabolism of
warfarin
Warfarin dose should be decreased when allopurinol is added
Allopurinol hypersensitivity syndrome correct answer Severe, can be life
threatening
Rash, fever, liver dysfunction, renal dysfunction
Stop allopurinol, seek medical attention
Don't take antihistamines
Baseline data: Bisphosphonates correct answer Axial DXA + height
Serum ca++ and vit. d
, Creatinine level/renal function
Pregnancy test
Baseline data: Denosumab correct answer DXA + height
Oral exam
Baseline ca++ and vit. d
Pregnancy test
Baseline data: Raloxifene correct answer DXA + height
Baseline ca++ and vit. d
Mammogram
Pregnancy test
Baseline diagnostic data: Conventional DMARDs correct answer ALT, AST, serum
creatinine
Baseline diagnostic data: Hydroxychloroquine correct answer Ophthalmic exam,
cardiac exam w/ ECG
Baseline diagnostic data: Leflunomide correct answer Chest x-ray, BP + pulmonary
status
Baseline diagnostic data: Methotrexate correct answer Chest x-ray, pulmonary +
GI status
