ANSWERS
A1C check correct answer every 3 months if unstable, if stable check every 6
months.
A1C correct answer goals: less than 7%, less than 8% in patients with severe
hypoglycemia, limited life expectancy, or advanced microvascular or
macrovascular complications.
adult goal is less than 8%
Absorption of levothyroxine REDUCED by: correct answer histamine 2 receptor
blockers (tagamet), proton pump inhibitors (lansoprazole), sucralfate (carafate),
Cholestyramine (Questran), Colestipol (colestid), aluminum containing antacids
(mylanta, maalox), calcium supplements (tums), iron supplements, magnesium
salts, orlistat.
*4 hours between levothyroxine and the above meds is recommended as well as
food
Action of Insulin correct answer anabolic-promotes conservation of energy and
buildup of energy stores (Glycogen)
- stimulates cellular transport (uptake) of glucose, amino acids, nucleotides & K
- promotes synthesis of complex molecules.
- promotes cellular growth and division
- energy conservation
, Basal insulin replacement correct answer encompasses approximately 50% of the
total daily insulin dose which replaces insulin from fasting (overnight) and
between meals. This dose is usually constant.
Bolus insulin replacement correct answer encompasses approximately 50% of the
total daily insulin dose and provides carbohydrate coverage and high blood sugar
correction. The bolus dose for carb or food coverage is prescribed as an insulin to
carb ration. Which represents how many grams of carbs are covered or disposed
of by 1 unit of insulin.
carb to insulin ratio correct answer 450 rule for regular insulin and the 500 rule
for rapid-acting insulin divided by TDD (0.6/units/kg/day)
Catecholamines correct answer increase cardiac responsiveness - at an increased
risk of catecholamine induced dysrhythmia.
Digoxin and insulin - may need to be increased if pt. is taking levothyroxine.
Diabetes EXCEPTIONS: correct answer patients with A1C greater than 9% or
greater start dual therapy (start at step 2) and patients with A1C greater than 10%
or fasting blood glucose of 300 or more/symptomatic may be started on
combination injectable therapy immediately.
DPP-4i: Dipeptidyl Peptidase-4 Inhibitors (Gliptins) correct answer Inhibits DPP-4
activity and increases active incretin concentration which results in increase
insulin secretion and decreased glucagon.
drugs less likely to cause hypoglycemia correct answer incretin mimetics,
metformin, thiazolidinediones, DPP-4 Inhibitors.