NR565- ADVANCE PHARMACOLOGY QUESTIONS WITH
ACCURATE ANSWERS
· Amlodipine
Common dose
Directions for use
Indication correct answer Essential HTN & Angina
5-10mg/daily
· Colchicine
Common dose
Directions for use
Indication correct answer Gout attack
start tx at the first sign of attack, and stop use is side effects occur
0.6-1.2mg q12-daily as recommended
· Hydrocodone/Acetaminophen (Lortab)
Common dose
Directions for use
Indication correct answer Pain
5mg/325mg- 1-2 tabs q4-6h
7.5mg/325mg- 1tab q4-6h
10mg/325mg- 1tab q4-6h
· Lisinopril
,Common dose
Directions for use
Indication correct answer HTN- 10-40 mg once/d
HF- 20-40 mg once/day
Acute MI- 10 mg once/day for at least 6 weeks
Atherosclerotic Cardiovascular Disease (ASCVD) Risk Score
o What is it?
o When is it used? correct answer ASCVD risk assessment is directed at
determining the patient's absolute risk of developing the clinical coronary disease
over the next 10 years. Defines high risk as 7.5% or greater. A calculation of your
10-year risk of having a cardiovascular problem, such as a heart attack or stroke.
In children, screening should be done between ages 9 and 11 and then again at
ages 19 and 21. For adults every 5 years after the age of 20. Some people are at
greater risk like those with diabetes and a risk score greater than 7.5% and should
be screened more often
Be familiar with pharmacokinetic and pharmacodynamic changes of older adults
and how that would translate to baseline information needed to prescribe.
correct answer increase glomerular filtration rate leads to increase drug excretion
increase hepatic metabolism
decrease tone and motility of bowel
increase drug absorption
Beer's Criteria- What is it and Why is it important correct answer
Recommendations of medications inappropriate for elderly (65 and older)
, Prevents adverse drug reactions
Behaviors that predict controlled substance addiction correct answer chronic pain
family history
other substance abuse
prescribed for long-term use
Best approach or drug to use for HTN during pregnancy or someone wishing to
become pregnant correct answer labetalol
methyldopa
nifedipine
Beta-blockers
o Their use with nitroglycerin and tachycardia
o Know examples
o Risk of stopping them abruptly
o What happens when given to someone with asthma? correct answer -Beta
Blockers suppress nitroglycerin-induced tachycardia.
They do so by preventing sympathetic activation of beta-1 adrenergic receptors in
the heart.
-End in -olol
-Stopping abruptly can increase the incidence and intensity of anginal attacks and
may even precipitate MI
-May cause bronchospasms
Black Box Warnings
ACCURATE ANSWERS
· Amlodipine
Common dose
Directions for use
Indication correct answer Essential HTN & Angina
5-10mg/daily
· Colchicine
Common dose
Directions for use
Indication correct answer Gout attack
start tx at the first sign of attack, and stop use is side effects occur
0.6-1.2mg q12-daily as recommended
· Hydrocodone/Acetaminophen (Lortab)
Common dose
Directions for use
Indication correct answer Pain
5mg/325mg- 1-2 tabs q4-6h
7.5mg/325mg- 1tab q4-6h
10mg/325mg- 1tab q4-6h
· Lisinopril
,Common dose
Directions for use
Indication correct answer HTN- 10-40 mg once/d
HF- 20-40 mg once/day
Acute MI- 10 mg once/day for at least 6 weeks
Atherosclerotic Cardiovascular Disease (ASCVD) Risk Score
o What is it?
o When is it used? correct answer ASCVD risk assessment is directed at
determining the patient's absolute risk of developing the clinical coronary disease
over the next 10 years. Defines high risk as 7.5% or greater. A calculation of your
10-year risk of having a cardiovascular problem, such as a heart attack or stroke.
In children, screening should be done between ages 9 and 11 and then again at
ages 19 and 21. For adults every 5 years after the age of 20. Some people are at
greater risk like those with diabetes and a risk score greater than 7.5% and should
be screened more often
Be familiar with pharmacokinetic and pharmacodynamic changes of older adults
and how that would translate to baseline information needed to prescribe.
correct answer increase glomerular filtration rate leads to increase drug excretion
increase hepatic metabolism
decrease tone and motility of bowel
increase drug absorption
Beer's Criteria- What is it and Why is it important correct answer
Recommendations of medications inappropriate for elderly (65 and older)
, Prevents adverse drug reactions
Behaviors that predict controlled substance addiction correct answer chronic pain
family history
other substance abuse
prescribed for long-term use
Best approach or drug to use for HTN during pregnancy or someone wishing to
become pregnant correct answer labetalol
methyldopa
nifedipine
Beta-blockers
o Their use with nitroglycerin and tachycardia
o Know examples
o Risk of stopping them abruptly
o What happens when given to someone with asthma? correct answer -Beta
Blockers suppress nitroglycerin-induced tachycardia.
They do so by preventing sympathetic activation of beta-1 adrenergic receptors in
the heart.
-End in -olol
-Stopping abruptly can increase the incidence and intensity of anginal attacks and
may even precipitate MI
-May cause bronchospasms
Black Box Warnings
