NR 565 PHARM MIDTERM QUESTIONS WITH ACCURATE
ANSWERS
ACE inhibitors MOA correct answer Inhibit ACE--> decrease angiotensin II-->
decrease GFR (prevent constriction of efferent arteriole)
Increasing levels of renin (loss of feedback)
ACE inhibition--> prevents inactivation of bradykinin (vasodilator)
USE FOR KIDNEY PROTECTION IN DM
Avoid in pregnancy
Aldosterone Antagonists (spironolactone) correct answer - Blocks actions of
aldosterone in distal nephron so K+ retained while Na excreted; binds to protein
that permits K+ secretion at distal tubule
- Usually used along with other diuretics.
- Response time: up to 48hrs
- Uses: HTN & hyperaldosteronism. Concurrently prescribed with thiazide or loop
diuretics to treat edema.
- SE: Hyperkalemia
Alendronate correct answer Fosamax
Patients need to sit upright for 3060 minutes after taking this medication and also
should watch for dietary supplement that may interfere with the absorption
Tom's calcium iron and magnesium
ARBs MOA correct answer block angiotensin receptor to reduce vasoconstriction
and aldosterone secretion
, ASCVD correct answer Used to determine patient's risk for disease and is used
when medication dosing for cholesterol is present. Can be used for patients that
have comorbidities.
Assessing for possible drug diversion correct answer Obtain a urine drug test and
utilize the PDMP
Beers Criteria for Potentially Inappropriate Medication Use in Older Adults correct
answer Potentially inappropriate medication used in adults due to medication
disease or medication syndrome interactions that may exacerbate the disease or
syndrome. Clinically significant drug interactions that should be avoided in older
adults there's decrease may need to be incorporated it due to decreased kidney
function
Behaviors that predict control substance addiction correct answer Use of drug for
prolong euphoria and able to get past undesirable effects of initial use people get
to this point from peer pressure who encouraged continued used to get the
desired effect
Beta Blockers correct answer decrease heart rate and dilate arteries by blocking
beta receptors; used with nitro during reflex tachycardia
Beta Blockers MOA correct answer Block sympathetic influence on the heart (esp
B1 selective), reducing CO and thus BP; also block renin release, stopping RAAS
system
Masks tachycardia and blood pressure and thyrotoxicosis,
examples are metoprolol propanolol labetolol, bidiptolollcarvedilol,
may also mass hypo glycemia
cannot give with asthma due to bronchospasm
ANSWERS
ACE inhibitors MOA correct answer Inhibit ACE--> decrease angiotensin II-->
decrease GFR (prevent constriction of efferent arteriole)
Increasing levels of renin (loss of feedback)
ACE inhibition--> prevents inactivation of bradykinin (vasodilator)
USE FOR KIDNEY PROTECTION IN DM
Avoid in pregnancy
Aldosterone Antagonists (spironolactone) correct answer - Blocks actions of
aldosterone in distal nephron so K+ retained while Na excreted; binds to protein
that permits K+ secretion at distal tubule
- Usually used along with other diuretics.
- Response time: up to 48hrs
- Uses: HTN & hyperaldosteronism. Concurrently prescribed with thiazide or loop
diuretics to treat edema.
- SE: Hyperkalemia
Alendronate correct answer Fosamax
Patients need to sit upright for 3060 minutes after taking this medication and also
should watch for dietary supplement that may interfere with the absorption
Tom's calcium iron and magnesium
ARBs MOA correct answer block angiotensin receptor to reduce vasoconstriction
and aldosterone secretion
, ASCVD correct answer Used to determine patient's risk for disease and is used
when medication dosing for cholesterol is present. Can be used for patients that
have comorbidities.
Assessing for possible drug diversion correct answer Obtain a urine drug test and
utilize the PDMP
Beers Criteria for Potentially Inappropriate Medication Use in Older Adults correct
answer Potentially inappropriate medication used in adults due to medication
disease or medication syndrome interactions that may exacerbate the disease or
syndrome. Clinically significant drug interactions that should be avoided in older
adults there's decrease may need to be incorporated it due to decreased kidney
function
Behaviors that predict control substance addiction correct answer Use of drug for
prolong euphoria and able to get past undesirable effects of initial use people get
to this point from peer pressure who encouraged continued used to get the
desired effect
Beta Blockers correct answer decrease heart rate and dilate arteries by blocking
beta receptors; used with nitro during reflex tachycardia
Beta Blockers MOA correct answer Block sympathetic influence on the heart (esp
B1 selective), reducing CO and thus BP; also block renin release, stopping RAAS
system
Masks tachycardia and blood pressure and thyrotoxicosis,
examples are metoprolol propanolol labetolol, bidiptolollcarvedilol,
may also mass hypo glycemia
cannot give with asthma due to bronchospasm
