ATI Practical Nursing (PN) Exam Prep | Questions with
Correct Answers | Latest Update 2026 | Graded A+
1. The nurse should instruct the patient taking allopurinol to discontinue their
medication if they notice which of the following adverse effects?
Excessive bleeding
Full body rash
Hyperglycemia
Tinnitus
2. Describe the significance of monitoring for adverse effects in patients on
long-term prednisone therapy.
Monitoring is only needed during the first month of therapy.
Monitoring is only required for patients with a history of allergies.
Monitoring for adverse effects is crucial because prednisone can
lead to serious complications such as osteoporosis and weight gain.
Monitoring is not necessary as prednisone has no significant side
effects.
3. A patient with ulcerative colitis is prescribed sulfasalazine and reports a new
rash after one week of treatment. What should the nurse's immediate action
be?
Notify the healthcare provider about the rash.
Instruct the patient to apply a topical cream to the rash.
Advise the patient to continue taking the medication as prescribed.
Schedule a follow-up appointment in one month.
,4. Describe the mechanism by which tamoxifen exerts its therapeutic effects in
breast cancer treatment.
Tamoxifen acts as an estrogen receptor modulator, blocking
estrogen's effects on breast tissue.
Tamoxifen increases estrogen production to inhibit cancer growth.
Tamoxifen enhances the immune response against cancer cells.
Tamoxifen directly kills cancer cells through cytotoxic effects.
5. Describe how tetracycline can lead to the development of oral candidiasis in
patients.
Tetracycline directly causes fungal infections without affecting flora.
Tetracycline can disrupt normal flora, leading to an overgrowth of
Candida.
Tetracycline has no relation to oral candidiasis.
Tetracycline enhances the immune response against Candida.
6. If a parent incorrectly states that cromolyn sodium can be used as a rescue
inhaler during an asthma attack, what should the nurse emphasize in their
teaching?
Cromolyn sodium is a preventive medication and should not be
used for immediate relief during an asthma attack.
Cromolyn sodium can be used as a rescue inhaler if symptoms are
severe.
Cromolyn sodium is effective for both prevention and immediate relief
of asthma symptoms.
Cromolyn sodium should be taken only when symptoms occur.
,7. The nurse understands that tamoxifen works by:
Allowing estrogen to attach to hormone receptors within the cancer
cells
Attacking and destroying cancer cells
Attaching to hormone receptors within the cancer cells, blocking
estrogen
Decreasing the hormone production of estrogen
8. What is the primary safety concern of the nurse when the patient takes
zolpidem for the treatment of short-term insomnia?
GI distress
N/D
Sleepwalking
Hypertension
9. If a patient taking ciprofloxacin develops tendon pain, what should the nurse
advise the patient to do?
Take over-the-counter pain relief without consulting a doctor.
Continue taking the medication as prescribed.
Increase physical activity to strengthen the tendons.
Discontinue the medication and report the symptoms to the
healthcare provider.
10. What is the primary use of cromolyn sodium in asthma management?
To relieve acute asthma symptoms
To reduce inflammation in the airways
, To prevent asthma attacks by stabilizing mast cells
To act as a bronchodilator
11. Why is it important to obtain a baseline ECG before starting a patient on
amitriptyline?
A baseline ECG is required to check the patient's cholesterol levels.
A baseline ECG helps in determining the patient's kidney function.
A baseline ECG is important to assess for any pre-existing cardiac
conditions that could be exacerbated by amitriptyline.
A baseline ECG is used to monitor blood glucose levels.
12. Order: 500ml 0.9%NS IV over 4 hours. Which rate should the nurse program
into the pump?
1000ml/hr
125ml/hr
167mm/hr
200ml/hr
13. A patient on chlorothiazide reports muscle weakness and fatigue. What
should the nurse assess for based on these symptoms?
Potassium levels
Kidney function
Liver enzymes
Blood pressure
Correct Answers | Latest Update 2026 | Graded A+
1. The nurse should instruct the patient taking allopurinol to discontinue their
medication if they notice which of the following adverse effects?
Excessive bleeding
Full body rash
Hyperglycemia
Tinnitus
2. Describe the significance of monitoring for adverse effects in patients on
long-term prednisone therapy.
Monitoring is only needed during the first month of therapy.
Monitoring is only required for patients with a history of allergies.
Monitoring for adverse effects is crucial because prednisone can
lead to serious complications such as osteoporosis and weight gain.
Monitoring is not necessary as prednisone has no significant side
effects.
3. A patient with ulcerative colitis is prescribed sulfasalazine and reports a new
rash after one week of treatment. What should the nurse's immediate action
be?
Notify the healthcare provider about the rash.
Instruct the patient to apply a topical cream to the rash.
Advise the patient to continue taking the medication as prescribed.
Schedule a follow-up appointment in one month.
,4. Describe the mechanism by which tamoxifen exerts its therapeutic effects in
breast cancer treatment.
Tamoxifen acts as an estrogen receptor modulator, blocking
estrogen's effects on breast tissue.
Tamoxifen increases estrogen production to inhibit cancer growth.
Tamoxifen enhances the immune response against cancer cells.
Tamoxifen directly kills cancer cells through cytotoxic effects.
5. Describe how tetracycline can lead to the development of oral candidiasis in
patients.
Tetracycline directly causes fungal infections without affecting flora.
Tetracycline can disrupt normal flora, leading to an overgrowth of
Candida.
Tetracycline has no relation to oral candidiasis.
Tetracycline enhances the immune response against Candida.
6. If a parent incorrectly states that cromolyn sodium can be used as a rescue
inhaler during an asthma attack, what should the nurse emphasize in their
teaching?
Cromolyn sodium is a preventive medication and should not be
used for immediate relief during an asthma attack.
Cromolyn sodium can be used as a rescue inhaler if symptoms are
severe.
Cromolyn sodium is effective for both prevention and immediate relief
of asthma symptoms.
Cromolyn sodium should be taken only when symptoms occur.
,7. The nurse understands that tamoxifen works by:
Allowing estrogen to attach to hormone receptors within the cancer
cells
Attacking and destroying cancer cells
Attaching to hormone receptors within the cancer cells, blocking
estrogen
Decreasing the hormone production of estrogen
8. What is the primary safety concern of the nurse when the patient takes
zolpidem for the treatment of short-term insomnia?
GI distress
N/D
Sleepwalking
Hypertension
9. If a patient taking ciprofloxacin develops tendon pain, what should the nurse
advise the patient to do?
Take over-the-counter pain relief without consulting a doctor.
Continue taking the medication as prescribed.
Increase physical activity to strengthen the tendons.
Discontinue the medication and report the symptoms to the
healthcare provider.
10. What is the primary use of cromolyn sodium in asthma management?
To relieve acute asthma symptoms
To reduce inflammation in the airways
, To prevent asthma attacks by stabilizing mast cells
To act as a bronchodilator
11. Why is it important to obtain a baseline ECG before starting a patient on
amitriptyline?
A baseline ECG is required to check the patient's cholesterol levels.
A baseline ECG helps in determining the patient's kidney function.
A baseline ECG is important to assess for any pre-existing cardiac
conditions that could be exacerbated by amitriptyline.
A baseline ECG is used to monitor blood glucose levels.
12. Order: 500ml 0.9%NS IV over 4 hours. Which rate should the nurse program
into the pump?
1000ml/hr
125ml/hr
167mm/hr
200ml/hr
13. A patient on chlorothiazide reports muscle weakness and fatigue. What
should the nurse assess for based on these symptoms?
Potassium levels
Kidney function
Liver enzymes
Blood pressure
