lOMoARcPSD|50207110
NR507 Midterm Exam – Advanced
Pathophysiology | Chamberlain |
Verified Questions & 100%, Exams
of Nursing Latest 2026
Advanced Pathophysiology (Chamberlain University)
, lOMoARcPSD|50207110
NR507 Midterm Practice Questions
1. 1. Which of the following is a Type I hypersensitivity reaction?
● A. Contact dermatitis
● B. Anaphylaxis
● C. SLE
● D. Rheumatic fever
Answer: B
Rationale: Anaphylaxis is mediated by IgE and mast cell degranulation, typical of Type I
hypersensitivity.
2. 2. Select all that apply: Symptoms of left-sided heart failure include:
● A. Dyspnea
● B. Orthopnea
● C. Pedal edema
● D. Crackles on auscultation
Answer: A, B, D
Rationale: Left-sided HF leads to pulmonary congestion causing dyspnea, orthopnea, and
crackles; edema is seen in right-sided HF.
3. 3. Which lab finding is most consistent with iron deficiency anemia?
● A. High MCV
● B. High ferritin
● C. Low TIBC
, lOMoARcPSD|50207110
● D. Low serum iron
Answer: D
Rationale: Iron deficiency anemia typically shows low serum iron and elevated TIBC.
4. 4. Which of the following conditions is associated with a restrictive pulmonary pattern?
● A. Asthma
● B. Emphysema
● C. ILD
● D. Chronic bronchitis
Answer: C
Rationale: Interstitial lung disease causes fibrosis and decreased lung compliance, a
hallmark of restrictive patterns.
5. 5. Which hormone stimulates red blood cell production in response to hypoxia?
● A. Renin
● B. Aldosterone
● C. Erythropoietin
● D. Cortisol
Answer: C
Rationale: Erythropoietin, produced by the kidneys, stimulates RBC production in response
to low oxygen.
6. 6. What lab finding is consistent with megaloblastic anemia?
● A. Low MCV
● B. High MCV
, lOMoARcPSD|50207110
● C. Low reticulocyte count
● D. High ferritin
Answer: B
Rationale: Megaloblastic anemia features high MCV due to impaired DNA synthesis.
7. 7. Which pulmonary disorder is associated with decreased DLCO?
● A. Asthma
● B. Emphysema
● C. Chronic bronchitis
● D. ILD
Answer: B
Rationale: Emphysema reduces alveolar surface area, decreasing DLCO.
8. 8. Which pulmonary disorder is associated with decreased DLCO?
● A. Asthma
● B. Emphysema
● C. Chronic bronchitis
● D. ILD
Answer: B
Rationale: Emphysema reduces alveolar surface area, decreasing DLCO.
9. 9. Select all that apply: Complications of chronic kidney disease include:
● A. Anemia
● B. Hyperphosphatemia
NR507 Midterm Exam – Advanced
Pathophysiology | Chamberlain |
Verified Questions & 100%, Exams
of Nursing Latest 2026
Advanced Pathophysiology (Chamberlain University)
, lOMoARcPSD|50207110
NR507 Midterm Practice Questions
1. 1. Which of the following is a Type I hypersensitivity reaction?
● A. Contact dermatitis
● B. Anaphylaxis
● C. SLE
● D. Rheumatic fever
Answer: B
Rationale: Anaphylaxis is mediated by IgE and mast cell degranulation, typical of Type I
hypersensitivity.
2. 2. Select all that apply: Symptoms of left-sided heart failure include:
● A. Dyspnea
● B. Orthopnea
● C. Pedal edema
● D. Crackles on auscultation
Answer: A, B, D
Rationale: Left-sided HF leads to pulmonary congestion causing dyspnea, orthopnea, and
crackles; edema is seen in right-sided HF.
3. 3. Which lab finding is most consistent with iron deficiency anemia?
● A. High MCV
● B. High ferritin
● C. Low TIBC
, lOMoARcPSD|50207110
● D. Low serum iron
Answer: D
Rationale: Iron deficiency anemia typically shows low serum iron and elevated TIBC.
4. 4. Which of the following conditions is associated with a restrictive pulmonary pattern?
● A. Asthma
● B. Emphysema
● C. ILD
● D. Chronic bronchitis
Answer: C
Rationale: Interstitial lung disease causes fibrosis and decreased lung compliance, a
hallmark of restrictive patterns.
5. 5. Which hormone stimulates red blood cell production in response to hypoxia?
● A. Renin
● B. Aldosterone
● C. Erythropoietin
● D. Cortisol
Answer: C
Rationale: Erythropoietin, produced by the kidneys, stimulates RBC production in response
to low oxygen.
6. 6. What lab finding is consistent with megaloblastic anemia?
● A. Low MCV
● B. High MCV
, lOMoARcPSD|50207110
● C. Low reticulocyte count
● D. High ferritin
Answer: B
Rationale: Megaloblastic anemia features high MCV due to impaired DNA synthesis.
7. 7. Which pulmonary disorder is associated with decreased DLCO?
● A. Asthma
● B. Emphysema
● C. Chronic bronchitis
● D. ILD
Answer: B
Rationale: Emphysema reduces alveolar surface area, decreasing DLCO.
8. 8. Which pulmonary disorder is associated with decreased DLCO?
● A. Asthma
● B. Emphysema
● C. Chronic bronchitis
● D. ILD
Answer: B
Rationale: Emphysema reduces alveolar surface area, decreasing DLCO.
9. 9. Select all that apply: Complications of chronic kidney disease include:
● A. Anemia
● B. Hyperphosphatemia
