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MRCP Official Exam 2026_2027 update _ questions and verified answers (complete solutions) GRADE A.pdf

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MRCP Official Exam 2026/2027 update |
questions and verified answers (complete
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A 65-year-old woman presented with A
a 12-hour history of the sudden onset
of gait unsteadiness, vomiting and
headache, followed by increasing
drowsiness.


What is the most likely diagnosis?


A: acute cerebellar haemorrhage


B: acute subdural haemorrhage


C: frontal subdural empyema


D: herpes simplex encephalitis


E: pituitary apoplexy

,A post-marketing observational E
study of a new drug was conducted
on 5000 patients following clinical
trials.


What best describes the data
generated from this type of study?



A: comparative efficacy


B: cost-benefit


C: cost effectiveness


D: potency


E: profile of adverse effects

,A 79-year-old woman was admitted B
for elective hip replacement surgery.
On examination, she was pale. There
was 2-cm splenomegaly and there
were small discrete axillary lymph
nodes.


haemoglobin 107 g/L (115-165)
white cell count 34.5 × 109/L (4.0-11.0)
platelet count 183 × 109/L (150-400)


What is the most likely diagnosis?



A: acute myeloid leukaemia


B: chronic lymphocytic leukaemia


C: chronic myeloid leukaemia


D: myelodysplasia


E: myelofibrosis

, A 17-year-old boy presented with a D
non-blanching rash over his legs, a
swollen knee and painless, visible
haematuria.


Urinalysis showed blood 3+, protein
1+.


serum creatinine 210 µmol/L (60-110)
urine culture negative ultrasound
scan of kidneys normal


What glomerular abnormality is most
likely to be present at renal biopsy?


A: focal segmental sclerosis


B: foot process fusion


C: linear deposition of IgG on the
basement membrane


D: mesangial deposition of IgA


E: thickening of basement
membranes

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