Page 1 of 64
AMT REGISTRY MLT EXAM |ACTUAL 200
QUESTIONS AND ANSWERS WITH
RATIONALES|ALREADY GRADED A+|100%
VERIFIED
1. The primary function of the erythrocyte (red blood cell) is:
A) Oxygen transport via hemoglobin
B) Immune defense against pathogens
C) Blood clotting
D) Inflammatory response
Correct Answer: A) Oxygen transport via hemoglobin
Rationale: RBCs contain hemoglobin, which binds oxygen in the
lungs and releases it to tissues. The other functions belong to
leukocytes (immune) and platelets (clotting).
2. What is the normal reference range for adult male
hemoglobin (g/dL)?
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A) 10–12 g/dL
B) 13.5–17.5 g/dL
C) 12–16 g/dL
D) 8–10 g/dL
Correct Answer: B) 13.5–17.5 g/dL (male); female: 12.0–15.5
g/dL
Rationale: Hemoglobin values vary by age, sex, and altitude.
Males have higher values due to androgenic stimulation of
erythropoiesis.
3. Scenario: A complete blood count (CBC) shows a WBC of
45,000/μL with 90% blasts. What is the most likely
diagnosis?
A) Iron deficiency anemia
B) Acute leukemia
C) Polycythemia vera
D) Aplastic anemia
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Correct Answer: B) Acute leukemia
Rationale: Very high WBC with circulating blasts (immature cells)
is characteristic of acute leukemia. A normal WBC is 4,500–
11,000/μL.
4. Which stain is used to visualize Heinz bodies (denatured
hemoglobin) on a blood smear?
A) Wright stain
B) Prussian blue
C) New methylene blue (supravital stain)
D) Giemsa stain
Correct Answer: C) New methylene blue (supravital stain)
Rationale: Heinz bodies are not visible with routine Wright stain.
Supravital staining (new methylene blue or brilliant cresyl blue)
precipitates them as dark inclusions.
5. A peripheral smear shows target cells (codocytes). Which
condition is most commonly associated with target cells?
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A) Iron deficiency anemia
B) Sickle cell anemia
C) Thalassemia and liver disease
D) Megaloblastic anemia
Correct Answer: C) Thalassemia and liver disease
Rationale: Target cells result from excess cell membrane relative
to hemoglobin. Seen in thalassemia, hemoglobin C disease, and
obstructive liver disease.
6. What is the principle of the Coulter (electrical impedance)
method for RBC counting?
A) Light scattering at 90 degrees
B) Electrical resistance as cells pass through an aperture
C) Flow cytometry with fluorescent dye
D) Measurement of hemoglobin absorbance
Correct Answer: B) Electrical resistance (impedance) as cells
pass through an aperture
AMT REGISTRY MLT EXAM |ACTUAL 200
QUESTIONS AND ANSWERS WITH
RATIONALES|ALREADY GRADED A+|100%
VERIFIED
1. The primary function of the erythrocyte (red blood cell) is:
A) Oxygen transport via hemoglobin
B) Immune defense against pathogens
C) Blood clotting
D) Inflammatory response
Correct Answer: A) Oxygen transport via hemoglobin
Rationale: RBCs contain hemoglobin, which binds oxygen in the
lungs and releases it to tissues. The other functions belong to
leukocytes (immune) and platelets (clotting).
2. What is the normal reference range for adult male
hemoglobin (g/dL)?
,Page 2 of 64
A) 10–12 g/dL
B) 13.5–17.5 g/dL
C) 12–16 g/dL
D) 8–10 g/dL
Correct Answer: B) 13.5–17.5 g/dL (male); female: 12.0–15.5
g/dL
Rationale: Hemoglobin values vary by age, sex, and altitude.
Males have higher values due to androgenic stimulation of
erythropoiesis.
3. Scenario: A complete blood count (CBC) shows a WBC of
45,000/μL with 90% blasts. What is the most likely
diagnosis?
A) Iron deficiency anemia
B) Acute leukemia
C) Polycythemia vera
D) Aplastic anemia
,Page 3 of 64
Correct Answer: B) Acute leukemia
Rationale: Very high WBC with circulating blasts (immature cells)
is characteristic of acute leukemia. A normal WBC is 4,500–
11,000/μL.
4. Which stain is used to visualize Heinz bodies (denatured
hemoglobin) on a blood smear?
A) Wright stain
B) Prussian blue
C) New methylene blue (supravital stain)
D) Giemsa stain
Correct Answer: C) New methylene blue (supravital stain)
Rationale: Heinz bodies are not visible with routine Wright stain.
Supravital staining (new methylene blue or brilliant cresyl blue)
precipitates them as dark inclusions.
5. A peripheral smear shows target cells (codocytes). Which
condition is most commonly associated with target cells?
, Page 4 of 64
A) Iron deficiency anemia
B) Sickle cell anemia
C) Thalassemia and liver disease
D) Megaloblastic anemia
Correct Answer: C) Thalassemia and liver disease
Rationale: Target cells result from excess cell membrane relative
to hemoglobin. Seen in thalassemia, hemoglobin C disease, and
obstructive liver disease.
6. What is the principle of the Coulter (electrical impedance)
method for RBC counting?
A) Light scattering at 90 degrees
B) Electrical resistance as cells pass through an aperture
C) Flow cytometry with fluorescent dye
D) Measurement of hemoglobin absorbance
Correct Answer: B) Electrical resistance (impedance) as cells
pass through an aperture
