UWORLD SELF ASSESSMENT EXAM SCRIPT
2026 FULL QUESTIONS AND CORRECT
ANSWERS
◉Drugs - inhibit 23SrRNA moiety of 50S ribosomal subunit. Answer:
Macrolides + clindamycin
◉Diagnosis - loose areolar tissue of the head and neck,
transilluminates with light. Answer: Cystic hygromas
◉Diagnosis - linear, erythematous rash after a hiking trip. Answer:
Poison ivy (hypersensitivity)
◉Mechanism - lactose deficiency in adults. Answer: Decreased gene
expression of lactase
◉Diagnosis - socially inappropriate sexual activity, oral fixation,
hyperphagia, visual agnosia, aphasia. Answer: Kluver-Bucy
syndrome (bilateral damage to temporal lobes) - due to HSV
encephalitis or traumatic brain injury
, ◉Part of urea cycle where urea is realsed. Answer: Hydrolysis of
arginine to ornithine
◉Urine pH in respiratory alkalosis. Answer: Increased/alkalinized
(kidney compensates by excreting bicarbonate)
◉Mechanism - tardive dyskinesia in antipsychotic medication use.
Answer: Upregulation of central dopamine receptors with a
decrease in cholinergic activity in the striatum
◉Enzyme - converts dopamine to NE. Answer: Dopamine
hydroxylase
◉Type of virus - adenovirus. Answer: Double-stranded DNA virus
(utilize DNA-dependent DNA polymerases to replicate their
genomes)
◉Diagnosis - painful pharyngeal muscle spasms with eosinophilic
cytoplasmic inclusions in hippocampul neurons (Negri bodies).
Answer: Rabies
◉Drug - synthetic retinoid used to treat psoriasis, strongly
teratogenic. Answer: Acitretin
2026 FULL QUESTIONS AND CORRECT
ANSWERS
◉Drugs - inhibit 23SrRNA moiety of 50S ribosomal subunit. Answer:
Macrolides + clindamycin
◉Diagnosis - loose areolar tissue of the head and neck,
transilluminates with light. Answer: Cystic hygromas
◉Diagnosis - linear, erythematous rash after a hiking trip. Answer:
Poison ivy (hypersensitivity)
◉Mechanism - lactose deficiency in adults. Answer: Decreased gene
expression of lactase
◉Diagnosis - socially inappropriate sexual activity, oral fixation,
hyperphagia, visual agnosia, aphasia. Answer: Kluver-Bucy
syndrome (bilateral damage to temporal lobes) - due to HSV
encephalitis or traumatic brain injury
, ◉Part of urea cycle where urea is realsed. Answer: Hydrolysis of
arginine to ornithine
◉Urine pH in respiratory alkalosis. Answer: Increased/alkalinized
(kidney compensates by excreting bicarbonate)
◉Mechanism - tardive dyskinesia in antipsychotic medication use.
Answer: Upregulation of central dopamine receptors with a
decrease in cholinergic activity in the striatum
◉Enzyme - converts dopamine to NE. Answer: Dopamine
hydroxylase
◉Type of virus - adenovirus. Answer: Double-stranded DNA virus
(utilize DNA-dependent DNA polymerases to replicate their
genomes)
◉Diagnosis - painful pharyngeal muscle spasms with eosinophilic
cytoplasmic inclusions in hippocampul neurons (Negri bodies).
Answer: Rabies
◉Drug - synthetic retinoid used to treat psoriasis, strongly
teratogenic. Answer: Acitretin
