QUESTIONS AND CORRECT ANSWERS
Etiology - CORRECT ANSWER Cause of particular disease on microscopic level
Pathogenesis - CORRECT ANSWER Story of how disease develops
Atrophy - CORRECT ANSWER Decrease in the size of the cells, results in reduced tissue mass
Hypertrophy - CORRECT ANSWER Increase in cell size, results in enlarged tissue mass
Hyperplasia - CORRECT ANSWER Increased number of cells, results in enlarged tissue mass
Metaplasia - CORRECT ANSWER Mature cell type is replaced by a different mature cell type,
Ex: chronic smokers, cells lose cilia
Dysplasia - CORRECT ANSWER Cells are different looking varying in size and shape
Neoplasia - CORRECT ANSWER New growth, commonly a tumor. May be malignant or
benign
Apoptosis - CORRECT ANSWER Programmed cell death, normal occurrence in the body
Ischemia - CORRECT ANSWER Deficit of oxygen in the cells
Hypoxia - CORRECT ANSWER Reduced oxygen in the tissues
Iatrogenic - CORRECT ANSWER illness or disease process because a medical process was
done ex: CAUTI
, Autosomal Recessive Disorders - CORRECT ANSWER Has to have two recessive genes to
have disease, only one recessive gene to be carrier ex: Cystic fibrosis, PKU (phenylketonuria), Tay-
Sachs
Cystic fibrosis - CORRECT ANSWER autosomal recessive disorder that causes thick mucous
secretions
PKU (phenylketonuria) - CORRECT ANSWER autosomal recessive disorder that causes an
inability to metabolize phenylalanine. Can cause mental retardation. Pt must follow strict very low
protein diet
Tay-Sachs - CORRECT ANSWER autosomal recessive disorder that causes an enzyme to not
be produced causing fatty proteins build up causing destruction of nerve cells in the brain and spinal
cord
Autosomal Dominant Disorders - CORRECT ANSWER Only takes one gene for disease to
show. There are no carriers, either have disease or don't. Marfan Syndrome, Huntington's, Familial
Hypercholesterolemia
Marfan Syndrome - CORRECT ANSWER Autosomal Dominant Disorder, causes long
extremities, congenital heart defects
Huntington's Disease - CORRECT ANSWER Autosomal Dominant Disorder, nerve cells break
down over time, causing involuntary movements
Familial Hypercholesterolemia - CORRECT ANSWER Autosomal Dominant Disorder, high
cholesterol
X-Linked Disorders - CORRECT ANSWER Disorder carried on the x chromosome
Recessive X-Linked Disorders - CORRECT ANSWER Color blindness, more prominent in
males, XcY male color blind, XcXc female color blind. XcX not color blind only carrier.
Chromosomal Disorder - CORRECT ANSWER not inherited, theres a problem on the
chromosome