NURS 5334 ANTIMICROBIALS EXAM
SCRIPT FINAL PAPER 2026 FULL SOLUTION
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◉ Antimicrobial.
Answer: Any agent of a natural or synthetic that can kill or suppress
micro-organisms
◉ Antimicrobial drugs classification by susceptible organism.
Answer: Narrow-spectrum antibiotics (preferred)
Broad-spectrum antibiotics
◉ Classified by mechanism of action.
Answer: Drugs that work on cell wall synthesis
Drugs that increase cell membrane permeability
Drugs that cause lethal inhibition of bacterial protein synthesis
Drugs that cause non-lethal inhibition of protein synthesis
Drugs that inhibit bacterial synthesis of DNA and RNA, or disrupt
DNA function
Anti-metabolites
Drugs that suppress viral replication
, ◉ Drugs that inhibit cell wall synthesis.
Answer: Penicillins and cephalosporins
Weaken cell wall, hence promote bacterial lysis and death
◉ Drugs that increase cell membrane permeability.
Answer: Amphotericin B
Increase the permeability of cell membranes causing leakage of
intracellular material
◉ Drugs that cause lethal inhibition of bacterial protein synthesis.
Answer: Aminoglycosides; gentamicin
◉ Drugs that cause non-lethal inhibition of protein synthesis.
Answer: Tetracyclines
Inhibit bacterial protein synthesis, and only slow microbial growth,
but do not kill the bacteria at clinically achievable concentrations
◉ Drugs that inhibit bacterial synthesis of DNA and RNA, or disrupt
DNA function.
Answer: Rifampin, metronidazole, and fluoroquinolones
SCRIPT FINAL PAPER 2026 FULL SOLUTION
VIEW AHEAD
◉ Antimicrobial.
Answer: Any agent of a natural or synthetic that can kill or suppress
micro-organisms
◉ Antimicrobial drugs classification by susceptible organism.
Answer: Narrow-spectrum antibiotics (preferred)
Broad-spectrum antibiotics
◉ Classified by mechanism of action.
Answer: Drugs that work on cell wall synthesis
Drugs that increase cell membrane permeability
Drugs that cause lethal inhibition of bacterial protein synthesis
Drugs that cause non-lethal inhibition of protein synthesis
Drugs that inhibit bacterial synthesis of DNA and RNA, or disrupt
DNA function
Anti-metabolites
Drugs that suppress viral replication
, ◉ Drugs that inhibit cell wall synthesis.
Answer: Penicillins and cephalosporins
Weaken cell wall, hence promote bacterial lysis and death
◉ Drugs that increase cell membrane permeability.
Answer: Amphotericin B
Increase the permeability of cell membranes causing leakage of
intracellular material
◉ Drugs that cause lethal inhibition of bacterial protein synthesis.
Answer: Aminoglycosides; gentamicin
◉ Drugs that cause non-lethal inhibition of protein synthesis.
Answer: Tetracyclines
Inhibit bacterial protein synthesis, and only slow microbial growth,
but do not kill the bacteria at clinically achievable concentrations
◉ Drugs that inhibit bacterial synthesis of DNA and RNA, or disrupt
DNA function.
Answer: Rifampin, metronidazole, and fluoroquinolones
