2026 SOLVED QUESTION SET GRADED A+
◉ medication for graves disease in pregnancy.
Answer: PTU - propylthiouracil
"Pregnancy Trimester Uno"
methimazole can be used for the rest of pregnancy after 1st
trimester
◉ cushing's disease.
Answer: high cortisol caused by pituitary tumor
tx: transsphenoidal surgery to remove adenoma
rx tx: dextamethasone to lower cortisol
s/s: weight gain of trunk, face, cervical areas, "buffalo hump", "moon
face" "truncal obesity"
◉ cushing's syndrome.
Answer: elevated cortisol caused by long term use of glucocorticoids
is main cause
s/s: oily skin, central obesity, thin extremities, striae on abdomen,
buffalo hump, purple striae, muscle weakness, easy bruising, poor
wound healing
,tx: gradual taper of steroids
risk of untreated: osteoporosis, infection, severe HTN
◉ Levothyroxine.
Answer: 1.6mcg/kg/day
treat subclinical when TSH >/=10
check TSH 4-6 weeks after start/adjusting therapy
elderly/comorbidities 12.5-25mcg/kg/day and adjust q4-6 weeks
◉ primary hypothyroid.
Answer: elevated TSH, decreased T4/T3
◉ subclinical hypothyroid.
Answer: elevated TSH, normal T4/T3
◉ hyperthyroidism.
Answer: low TSH, high T3/T4
s/s: goiter, exophthalmos, pretibial myxedema, heat intolerance,
weight loss, tremors, tachycardia, insomnia, hyperreflexia, light
periods
◉ addisonian crisis.
, Answer: life threatening cortisol deficiency
triggered by stress, illness, steroid withdrawal
s/s: hypotension, shock, hyponatremia, hyperkalemia
tx: IV hydrocortisone, fluids, correct electrolytes, glucose
◉ hyperparathyroidism.
Answer: primary: increased PTH, increased Calcium, decreased phos
secondary: increased PTH, decreased/normal calcium, increased
phos
Tx: parathyroidectomy
◉ tx for hypoparathyroidism.
Answer: calcium and vitamin D
◉ pretibial myxedema.
Answer: brown patches to lower extremities in pts with graves
disease, nonpitting edema, bilateral, scaly
◉ diabetic gastroparesis.
Answer: delayed gastric emptying from years of damage from
diabetes
s/s: early satiety, epigastric discomfort, postprandial nausea and
bloating