NSG 552 PsychoPharmacology Wilkes Exam 3
Study Guide Fall 2026 Questions and Answers
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Terms in this set (81)
First Line Treatments for alcohol use naltrexone and acamprosate
disorder (according to Study Guide
& Dynamed)
Second Line Treatments for alcohol Disulfuram and Bupropion (not FDA approved for
use disorder (according to study ETOH but second line according to study guide)
guide but not dynamed)
Second Line Treatment for alcohol Disulfuram
use disorder (according to
Dynamed)
Other off label medications for Topiramate, gabapentin, baclofen
alcohol use disorder according to
Dynamed
, Other off label medications for Topiramate, ondansetron
alcohol use disorder according to
Stahl's
MOA of Naltrexone Opioid Receptor Antagonist
MOA of Acamprosate - weak GABAa agonist
- weak NMDA antagonist
(does not prevent withdrawal symptoms)
MOA of Disulfuram inhibits enzyme (aldehyde dehydrogenase) in the
liver
Bupropions role in alcohol use Can diminish cravings for etoh, treat underlying
disorder anxiety/depression
Safety Risk associated with bupropion increases the risk of seizures in those
bupropion and etoh going through etoh withdrawal
s/s ETOH intoxication impaired fine motor control, impaired judgement
and coordination, ataxic gait, poor balance,
lethargy, difficulty sitting upright, difficulty with
memory and sitting upright, N/V, coma in levels
300mg/dL and over with respiratory depression
and death possible
S/S of etoh withdrawal Mild: insomnia, irritability, hand tremor
Moderate: autonomic hyperactivity (diaphoresis,
tachycardia, HTN), fever
Severe: seizures (12-48 hours post consumption),
hallucinations, Delirium Tremens
Study Guide Fall 2026 Questions and Answers
Save
Terms in this set (81)
First Line Treatments for alcohol use naltrexone and acamprosate
disorder (according to Study Guide
& Dynamed)
Second Line Treatments for alcohol Disulfuram and Bupropion (not FDA approved for
use disorder (according to study ETOH but second line according to study guide)
guide but not dynamed)
Second Line Treatment for alcohol Disulfuram
use disorder (according to
Dynamed)
Other off label medications for Topiramate, gabapentin, baclofen
alcohol use disorder according to
Dynamed
, Other off label medications for Topiramate, ondansetron
alcohol use disorder according to
Stahl's
MOA of Naltrexone Opioid Receptor Antagonist
MOA of Acamprosate - weak GABAa agonist
- weak NMDA antagonist
(does not prevent withdrawal symptoms)
MOA of Disulfuram inhibits enzyme (aldehyde dehydrogenase) in the
liver
Bupropions role in alcohol use Can diminish cravings for etoh, treat underlying
disorder anxiety/depression
Safety Risk associated with bupropion increases the risk of seizures in those
bupropion and etoh going through etoh withdrawal
s/s ETOH intoxication impaired fine motor control, impaired judgement
and coordination, ataxic gait, poor balance,
lethargy, difficulty sitting upright, difficulty with
memory and sitting upright, N/V, coma in levels
300mg/dL and over with respiratory depression
and death possible
S/S of etoh withdrawal Mild: insomnia, irritability, hand tremor
Moderate: autonomic hyperactivity (diaphoresis,
tachycardia, HTN), fever
Severe: seizures (12-48 hours post consumption),
hallucinations, Delirium Tremens