Page 1 of 142
WOUND CARE NURSE CERTIFICATION
(CWCN) FINAL EXAM
|220+QS&AS|A+GRADE|NEW UPDATE
1. The initial phase of wound healing, which begins
immediately after injury, is the:
A) Proliferative phase
B) Maturation phase
C) Inflammatory phase
D) Hemostasis phase
Answer: D
Rationale: Hemostasis occurs within seconds to minutes,
involving vasoconstriction and platelet aggregation to form
a clot. The inflammatory phase follows.
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2. Which cell type is the first to arrive at a wound site to
phagocytize debris and bacteria?
A) Lymphocytes
B) Macrophages
C) Neutrophils
D) Fibroblasts
Answer: C
Rationale: Neutrophils are the first leukocytes to migrate
into the wound (within hours). They are followed by
macrophages, which arrive later (2–3 days).
3. The proliferative phase of wound healing is characterized
by:
A) Platelet aggregation and clot formation
B) Angiogenesis, granulation tissue formation, and
re-epithelialization
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C) Collagen remodeling and increased tensile strength
D) Neutrophil infiltration
Answer: B
Rationale: Proliferative phase (days 3–21) includes
formation of granulation tissue (fibroblasts, collagen,
capillaries), wound contraction, and epithelialization.
4. Which growth factor is primarily responsible for stimulating
angiogenesis?
A) Platelet-derived growth factor (PDGF)
B) Transforming growth factor-beta (TGF-β)
C) Vascular endothelial growth factor (VEGF)
D) Epidermal growth factor (EGF)
Answer: C
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Rationale: VEGF is a key promoter of new blood vessel
formation (angiogenesis) during wound healing.
5. The maturation (remodeling) phase can last for:
A) 1–2 weeks
B) 3–4 weeks
C) 6 months to 2 years
D) 3–5 years
Answer: C
Rationale: Remodeling begins at about day 21 and can
continue for up to 2 years. Collagen is reorganized, and
tensile strength increases to about 80% of original tissue.
6. Which vitamin deficiency is most strongly associated with
impaired wound healing?
A) Vitamin A
WOUND CARE NURSE CERTIFICATION
(CWCN) FINAL EXAM
|220+QS&AS|A+GRADE|NEW UPDATE
1. The initial phase of wound healing, which begins
immediately after injury, is the:
A) Proliferative phase
B) Maturation phase
C) Inflammatory phase
D) Hemostasis phase
Answer: D
Rationale: Hemostasis occurs within seconds to minutes,
involving vasoconstriction and platelet aggregation to form
a clot. The inflammatory phase follows.
,Page 2 of 142
2. Which cell type is the first to arrive at a wound site to
phagocytize debris and bacteria?
A) Lymphocytes
B) Macrophages
C) Neutrophils
D) Fibroblasts
Answer: C
Rationale: Neutrophils are the first leukocytes to migrate
into the wound (within hours). They are followed by
macrophages, which arrive later (2–3 days).
3. The proliferative phase of wound healing is characterized
by:
A) Platelet aggregation and clot formation
B) Angiogenesis, granulation tissue formation, and
re-epithelialization
,Page 3 of 142
C) Collagen remodeling and increased tensile strength
D) Neutrophil infiltration
Answer: B
Rationale: Proliferative phase (days 3–21) includes
formation of granulation tissue (fibroblasts, collagen,
capillaries), wound contraction, and epithelialization.
4. Which growth factor is primarily responsible for stimulating
angiogenesis?
A) Platelet-derived growth factor (PDGF)
B) Transforming growth factor-beta (TGF-β)
C) Vascular endothelial growth factor (VEGF)
D) Epidermal growth factor (EGF)
Answer: C
, Page 4 of 142
Rationale: VEGF is a key promoter of new blood vessel
formation (angiogenesis) during wound healing.
5. The maturation (remodeling) phase can last for:
A) 1–2 weeks
B) 3–4 weeks
C) 6 months to 2 years
D) 3–5 years
Answer: C
Rationale: Remodeling begins at about day 21 and can
continue for up to 2 years. Collagen is reorganized, and
tensile strength increases to about 80% of original tissue.
6. Which vitamin deficiency is most strongly associated with
impaired wound healing?
A) Vitamin A
