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PERIOPERATIVE NURSING EXAM | 200 QUESTIONS + RATIONALES | CNOR & NIFA CERTIFICATION PREP

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Pass Your Perioperative Certification (CNOR/NIFA) on the First Attempt! This comprehensive practice exam features 200 realistic questions and answers with detailed rationales, based on the latest AORN, ASA, and WHO Surgical Safety guidelines. Covers all exam topics: preoperative assessment (NPO, medications, allergy management, anticoagulation reversal), intraoperative asepsis (sterile field, surgical counts, electrosurgery safety, positioning, malignant hyperthermia, latex allergy), anesthesia principles (induction agents, neuromuscular blockade, reversal, local anesthetic toxicity, MH treatment), PACU recovery (Aldrete score, PONV, respiratory depression, pain management), and postoperative complications (DVT, PE, surgical site infection, TURP syndrome, ileus, compartment syndrome). Written for perioperative nurses, CNOR candidates, and surgical first assistants—master time-out protocols, fire triangle prevention, tourniquet safety, specimen handling, and emergency response (venous air embolism, trigeminocardiac reflex). Includes questions 1–200 with complete answer key and rationales. No fluff—just exam-focused preparation!

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Institution
2026-2027 PERIOPERATIVE NURSING
Course
2026-2027 PERIOPERATIVE NURSING

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Page 1 of 145



Perioperative Quiz 1 & 2 Actual Exam

2026/2027 – Complete Exam-Style

Questions with Detailed Rationales |

100% Verified | Pass Guaranteed – A+

Graded

1. A patient scheduled for elective cholecystectomy reports

taking aspirin 81 mg daily for primary prevention. The surgeon

asks you to cancel the surgery. What is the most appropriate

action?

A) Proceed with surgery because low-dose aspirin does not

increase bleeding risk.

B) Cancel the surgery and advise the patient to stop aspirin 7-10

days before rescheduling.

,Page 2 of 145


C) Give the patient vitamin K to reverse the aspirin effect.

D) Administer protamine sulfate before surgery.

Answer: B

Rationale: Aspirin irreversibly inhibits cyclooxygenase, affecting

platelet function for 7-10 days (life of platelet). For most elective

surgeries, aspirin should be stopped 5-7 days prior. Option A is

incorrect – low-dose aspirin still increases bleeding. Vitamin K

reverses warfarin, not aspirin. Protamine reverses heparin.

2. A patient with type 2 diabetes takes metformin 1000 mg BID.

He is scheduled for coronary artery bypass grafting (CABG).

Regarding metformin, you should:

A) Continue metformin as usual on the morning of surgery.

B) Hold metformin on the day of surgery and for 48 hours

postoperatively due to risk of lactic acidosis.

C) Double the dose to improve glycemic control.

D) Switch to insulin the day before surgery.

,Page 3 of 145


Answer: B

Rationale: Metformin is held before and after surgery (typically

48 hours) because of the risk of lactic acidosis, especially in

patients with reduced renal perfusion or contrast dye exposure.

Insulin is used for glycemic control perioperatively when needed.

3. A patient with a hip fracture requires emergency surgery. She

takes warfarin for atrial fibrillation, and her INR is 3.2. Which

intervention is most appropriate?

A) Proceed with surgery – INR 3.2 is safe.

B) Administer fresh frozen plasma (FFP) and vitamin K to reverse

anticoagulation.

C) Delay surgery for 5 days until INR <1.5.

D) Give protamine sulfate.

Answer: B

Rationale: For emergency surgery, rapid reversal of warfarin is

needed. FFP provides clotting factors, and vitamin K (slow)

, Page 4 of 145


supports synthesis. INR should be ≤1.5 for most surgeries. Delay

is not possible for a hip fracture. Protamine reverses heparin.

4. A patient is NPO for 8 hours before surgery. He has been

sipping water up to 2 hours before the scheduled time. What is

your action?

A) Cancel surgery because any oral intake within 4 hours is

unsafe.

B) Proceed with surgery – clear liquids up to 2 hours before

general anesthesia are allowed per ASA guidelines.

C) Cancel and reschedule for next week.

D) Give a full stomach protocol only if he ate solid food.

Answer: B

Rationale: ASA guidelines allow clear liquids up to 2 hours

before elective procedures. Small volumes of water are not

associated with increased aspiration risk.

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Institution
2026-2027 PERIOPERATIVE NURSING
Course
2026-2027 PERIOPERATIVE NURSING

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Uploaded on
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Number of pages
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Written in
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Type
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