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VETERINARY TECHNICIAN NATIONAL EXAMINATION (VTNE) – 200+ PRACTICE QUESTIONS & ANSWERS | PHARMACOLOGY, ANESTHESIA, SURGERY, LABORATORY & EMERGENCY MEDICINE

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Pass the Veterinary Technician National Examination (VTNE) with confidence using this comprehensive 200+ question practice guide! Covers pharmacology (dose calculations – carprofen, gentamicin, dexmedetomidine; drug classifications – Schedule II/III/IV controlled substances; contraindications – acetaminophen toxicity in cats; reconstitution calculations; propofol adverse effects; reversal agents – atipamezole), anesthesia and analgesia (premedication, induction, monitoring, bradycardia management, hypothermia protocols, NMDA antagonists – amantadine), surgical nursing (instrument identification – Kelly forceps, Mayo vs. Metzenbaum scissors; suture materials – absorbable monofilament PDS; surgical hand scrub sequence; ovariohysterectomy), laboratory procedures (blood smear inclusions – Howell-Jolly bodies, Heinz bodies; PCV interpretation – polycythemia, dehydration; urine specific gravity; tube additives – lithium heparin for plasma chemistry; hyperkalemia ECG changes – tall T waves, wide QRS), diagnostic imaging (thoracic and abdominal radiograph positioning; normal mandibular canal vs. fracture), emergency medicine (GDV – pulsus paradoxus, priority actions; urethral obstruction in male cats – hyperkalemia, slow decompression; CPR compression:ventilation ratios with advanced airway; hypothermia rewarming; calcium gluconate extravasation risk; laminitis in horses; anthrax in cattle), animal care and nutrition (hepatic encephalopathy – protein restriction; IRIS stage 2 CKD – phosphorus restriction; feline heartworm), dental disease (grading periodontitis), pain management, zoonotic diseases (Toxocara canis – visceral larva migrans), and unfolding case studies. Every question includes the correct answer and a detailed rationale — updated for 2026 VTNE standards. Perfect for veterinary technician students, RVTs, LVTs, CVTs, and VTNE certification candidates. Download instantly and ace your VTNE with confidence!

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Institution
VETERINARY TECHNICIAN
Course
VETERINARY TECHNICIAN

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Page 1 of 34



Veterinary Technician National

Examination (VTNE) Exam Questions with

Answers and Rationales| Instant

Download PDF

1. A 20 kg dog is prescribed carprofen at 2.2 mg/kg IV once.

What is the dose in mg?

A. 22 mg

B. 44 mg

C. 11 mg

D. 88 mg

Answer: B – 44 mg

Rationale: 20 kg × 2.2 mg/kg = 44 mg.

,Page 2 of 34


2. Which drug is contraindicated in cats due to risk of severe

toxicity?

A. Meloxicam

B. Acetaminophen

C. Buprenorphine

D. Maropitant

Answer: B – Acetaminophen

Rationale: Cats lack glucuronyl transferase →

methemoglobinemia and Heinz body hemolytic anemia. Even one

extra-strength tablet can be fatal.




3. A horse is prescribed gentamicin (6.6 mg/kg IV q24h). The

concentration is 100 mg/mL. How many mL for a 500 kg

horse?

A. 33 mL

B. 66 mL

,Page 3 of 34


C. 16.5 mL

D. 3.3 mL

Answer: A – 33 mL

Rationale: 500 kg × 6.6 = 3300 mg ÷ 100 mg/mL = 33 mL.




4. Which of the following is a Schedule II controlled

substance?

A. Butorphanol

B. Buprenorphine

C. Fentanyl

D. Tramadol

Answer: C – Fentanyl

Rationale: DEA schedule: Fentanyl (II), Buprenorphine (III),

Butorphanol (III/IV), Tramadol (IV).

, Page 4 of 34


5. A veterinary technician reconstitutes 1 g of cefazolin

powder with 10 mL sterile water to yield 100 mg/mL. How

much volume is needed for a 250 mg dose?

A. 0.25 mL

B. 2.5 mL

C. 5 mL

D. 1 mL

Answer: B – 2.5 mL

Rationale: 250 mg ÷ 100 mg/mL = 2.5 mL.




SURGICAL NURSING

6. During routine ovariohysterectomy, the surgeon asks for a

hemostat to clamp the suspensory ligament. Which instrument

is most appropriate?

A. Kelly forceps

B. Mayo scissors

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Course
VETERINARY TECHNICIAN

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