What generation of antihistamines have a higher water solubility?
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1st generation (2nd gen has low water solubility)
What is concerned with the drug dose and plasma concentration?
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pharmacokinetics
Protein bound % of H2 antagonists?
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13-35%
True or False. Skin rash is a side effect of clindamycin.
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True, in 10% of patients
PO vancomycin is only used for what two things because it is poorly absorbed orally?
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staph enterocolitis
antimicrobial-associated pseudomembranous enterocolitis
Bradykinin mediates the release of what 3 neuropeptides?
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Substance P
calcitonin peptide
neurokinin
,What is the normal IV dose of vancomycin to be infused over 60 minutes?
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10-15 mg/kg (when given over an hour, histamine release is minimized and
plasma concentrations are maintained over 12 hours)
What drugs inhibit hepatic enzymes which metabolize drugs?
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antibiotics
cimetidine
What two ways do locally-administered drugs reach their effect site?
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diffusion or absorption through tissues
Which histamine receptor causes positive inotropic effects?
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, H2 and the ability of histamine to cause catecholamine release from the
adrenal medulla
What blocks H2 receptors in the CNS?
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lysergic acid diethylamide
Onset and duration of action for Atrovent?
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Effects in 30-90 minutes lasting 4 hours
What is minimum inhibitory concentration of antibiotics?
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the lowest concentration of a given antimicrobial at which an organism's
growth is inhibited.
Which antibiotic is stable in the presence of gastic acid, making it well-absorbed from
the GI tract?
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Give this one a try later!
1st generation (2nd gen has low water solubility)
What is concerned with the drug dose and plasma concentration?
Give this one a try later!
pharmacokinetics
Protein bound % of H2 antagonists?
,Give this one a try later!
13-35%
True or False. Skin rash is a side effect of clindamycin.
Give this one a try later!
True, in 10% of patients
PO vancomycin is only used for what two things because it is poorly absorbed orally?
Give this one a try later!
staph enterocolitis
antimicrobial-associated pseudomembranous enterocolitis
Bradykinin mediates the release of what 3 neuropeptides?
Give this one a try later!
Substance P
calcitonin peptide
neurokinin
,What is the normal IV dose of vancomycin to be infused over 60 minutes?
Give this one a try later!
10-15 mg/kg (when given over an hour, histamine release is minimized and
plasma concentrations are maintained over 12 hours)
What drugs inhibit hepatic enzymes which metabolize drugs?
Give this one a try later!
antibiotics
cimetidine
What two ways do locally-administered drugs reach their effect site?
Give this one a try later!
diffusion or absorption through tissues
Which histamine receptor causes positive inotropic effects?
Give this one a try later!
, H2 and the ability of histamine to cause catecholamine release from the
adrenal medulla
What blocks H2 receptors in the CNS?
Give this one a try later!
lysergic acid diethylamide
Onset and duration of action for Atrovent?
Give this one a try later!
Effects in 30-90 minutes lasting 4 hours
What is minimum inhibitory concentration of antibiotics?
Give this one a try later!
the lowest concentration of a given antimicrobial at which an organism's
growth is inhibited.
Which antibiotic is stable in the presence of gastic acid, making it well-absorbed from
the GI tract?
Give this one a try later!
