GCD 3022 - Exam 2 Book Questions With Complete Solutions

GCD 3022 - Exam 2 Book Questions With Complete
Solutions

12.1.1. Which of the following base sequences is used during
transcription?

a. promoter and terminator
b. start and stop codons
c. ribosome-binding site
d. both a and b Correct Answers a. promoter and terminator

12.1.2. The three stages of transcription are

a. initiation, ribosome binding, and termination
b. elongation, ribosome binding, and termination
c. initiation, elongation, and termination
d. initiation, regulation, and termination Correct Answers c.
initiation, elongation, and termination

12.2.1. Within a promoter, a transcriptional start site is

a. located at the -35 sequence and is recognized by sigma factor
b. located at the -35 sequence and is where the first base is used
as a template for transcription
c. located at the +1 site and is recognized by sigma factor
d. located at the +1 sequence and is where the first base is used
as a template for transcription Correct Answers d. located at
the +1 sequence and is where the first base is used as a template
for transcription

,12.2.2. For the following five sequences, what is the consensus
sequence?

5'-GGGAGCG-3'
5'-GAGAGCG-3'
5'-GAGTGCG-3'
5'-GAGAACG-3'
5'-GAGAGCA-3'

a. 5'-GGGAGCG-3'
b. 5'-GAGAGCG-3'
c. 5'-GAGTGCG-3'
d. 5'-GAGAACG-3' Correct Answers b. 5'-GAGAGCG-3'

12.2.3. Sigma (σ) factor is needed during which stage(s) of
transcription?

a. initiation
b. elongation
c. termination
d. all of the above Correct Answers a. initiation

12.2.4. A uracil-rich sequence occurs at the end of the RNA in

a. ρ-dependent termination
b. ρ-independent termination
c. both a and b
d. none of the above Correct Answers b. ρ-independent
termination

,12.3.1. Which RNA polymerase in eukaryotes is responsible for
the transcription of genes that encode proteins?

a. RNA polymerase I
b. RNA polymerase II
c. RNA polymerase III
d. all of the above transcribe protein-encoding genes Correct
Answers b. RNA polymerase II

12.3.2. An enhancer is a _______ that _______ the rate of
transcription

a. trans-acting factor, increases
b. trans-acting factor, decreases
c. cis-acting element, increases
d. cis-acting element, decreases Correct Answers c. cis-acting
element, increases

12.3.3. The basal transcription apparatus is composed of

a. five general transcription factors
b. RNA polymerase II
c. a DNA sequence containing a TATA box and transcriptional
start site
d. all of the above Correct Answers d. all of the above

12.3.4. With regard to transcriptional termination in eukaryotes,
which model(s) suggest(s) that RNA polymerase is physically
removed from the DNA?

a. allosteric model

, b. torpedo model
c. both models
d. neither model Correct Answers b. torpedo model

12.4.1. Which of the following are examples of RNA
modifications?

a. splicing
b. capping with a 7-methylguanosine
c. adding a polyA tail
d. all of the above are examples of RNA modifications Correct
Answers d. all of the above are examples of RNA modifications

12.4.2. A ribozyme is

a. a complex between RNA and protein
b. an RNA that encodes a protein that functions as an enzyme
c. an RNA molecule with catalytic function
d. a protein that degrades RNA molecules Correct Answers c.
an RNA molecule with catalytic function

12.4.3. Which of the following statements about a spliceosome
is false?

a. a spliceosome splices pre-mRNA molecules
b. a spliceosome removes exons from RNA molecules
c. a spliceosome is composed of snRNPs
d. a spliceosome recognizes the exon-intron boundaries and the
branch site Correct Answers b. a spliceosome removes exons
from RNA molecules