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DE SOUZA CHEMOTHERAPY QUESTIONS AND VERIFIED ANSWERS

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DE SOUZA CHEMOTHERAPY QUESTIONS AND VERIFIED ANSWERS

Institution
Chemotherapy
Course
Chemotherapy

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What chemo must be diluted in D5W
A)Doxorubicin
B)Peglated liposomal doxorubicin
C)Doxorubicin
D)Bleomycin


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B)




Cell cycle nonspecific agents fall into these classes
Alkylating agents
Anti-tumor antibiotics
Nitrourea agent
The subclasses of these are


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, Alkylating : nitrogen mustards , platinum compounds


Anti-tumor antibiotics : anthracyclines, Anthracenediones,
Mitomycin and Bleomycin

Nitrourea agent: strephtozocin




Po Temozolomide should be taken how


A) with food
B) capsule can be opened and mixed with food
C) be taken on an empty stomach 30 min prior to food
D) taken on an empty stomach at least one hour before food.


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D) taken on an empty stomach at least one hour before food.




These adverse does limiting effects belong to what drug
-insulin shock
Nephrotoxicity in 75% of patients
A) doxorubicin
B) Pegylated liposomal doxorubicin
C)Cisplatin
D) streptozocin
E) Bleomycin


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D) streptozocin

,These toxicities correlate with what drug?Neutropenia ,Nausea ,
Vomiting,Hypersensitivity reactions, Skin rash


A)Carboplatin
B)Cisplatin
C)Oxaliplatin
D)Cyclophosphamide


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A) carboplatin




3 Subclasses of Antitumor antibiotics are


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Anthracyclines
Anthracenediones
Other Antitumor antibiotics




Cell cycle non-specific chemotherapy agents affect cells in all phases of the cell
cycle, except for G0
True or false


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False: the resting phase or G0 is also effected

, Normal ejection fraction from a MUGA


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55-75%




Insulin shock from Streptozocin occurs


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within 24 hours of administration




Antitumor antibiotics ( Anthracenediones ) use the following methods to kill cancer
cells except
1)Intercalation of DNA
2)formation of oxygen free radicals
3) inhibition of topoisomerase II
4) formation of DNA cross links


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2)formation of oxygen free radicals




drugs in anthracyclines category are


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Institution
Chemotherapy
Course
Chemotherapy

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