Act in the S phase of cell cycle and do not allow cells to leave the S phase of the cell
cycle, interfering with DNA synthesis.
Side Effects: N/V, mucositis, GI toxicity
5FU, methotrexate, leucovorin, hydroxyurea, cytarabine
Give this one a try later!
Antimetabolites
alkylating agent, Used in combination with IV 5FU and Leucovorin for adjuvant
treatment of colorectal cancer
Routes : IV
Acute Side Effects: Pulmonary Fibrosis
,Serious Side Effects: Severe peripheral neuropathies, including acute (reversible) and
cumulative
Give this one a try later!
Oxaliplatin
Wash for 15 minutes at eye wash station with water or normal saline
Give this one a try later!
Exposure to Eyes
cell cycle nonspecific, exert effect in all phases of cell cycle. Cause breaks in DNA via
alkylation, interfering with DNA replication. Carboplatin, cisplatin, ifosfamide,
cyclophosphamide.
Give this one a try later!
Alkylating agents
RN must verify accuracy of dose
Manipulation/Crushing of pills must be done within a biologic safety cabinet
Give this one a try later!
Oral Chemotherapy
, Wear 1 pair of chemotherapy gloves when handling intact tablets or
capsules
anticancer drugs applied directly to the skin surface
may be used in vulvar cancer with topical 5FU or imiquimod
Give this one a try later!
topical chemotherapy
* Fever and chills occur in majority of patients with first dose
* Consider premedication with acetaminophen and diphenhydramine
* If infusion reaction occurs, patient may need premedication with steroids in future.
* Transient hypotension can occur, hold antihypertensives for 12 hours
Give this one a try later!
Rituximab (Rituxan, monoclonal antibody, chimeric): IV administration with
rate escalation starting at 50 mg/hour
Treatment of certain types of non-Hodgkin's lymphoma, chronic
lymphocytic leukemia (CLL), rheumatoid arthritis
Rituximab works by targeting the CD20 antigen on normal and malignant
B-cells.
Then the body's natural immune defenses are recruited to attack and kill the
marked B-cells.
Stem cells (young cells in the bone marrow that will develop into the
various types of cells) do not have the CD20 antigen. This allows healthy B-
cells to regenerate after treatment.
cycle, interfering with DNA synthesis.
Side Effects: N/V, mucositis, GI toxicity
5FU, methotrexate, leucovorin, hydroxyurea, cytarabine
Give this one a try later!
Antimetabolites
alkylating agent, Used in combination with IV 5FU and Leucovorin for adjuvant
treatment of colorectal cancer
Routes : IV
Acute Side Effects: Pulmonary Fibrosis
,Serious Side Effects: Severe peripheral neuropathies, including acute (reversible) and
cumulative
Give this one a try later!
Oxaliplatin
Wash for 15 minutes at eye wash station with water or normal saline
Give this one a try later!
Exposure to Eyes
cell cycle nonspecific, exert effect in all phases of cell cycle. Cause breaks in DNA via
alkylation, interfering with DNA replication. Carboplatin, cisplatin, ifosfamide,
cyclophosphamide.
Give this one a try later!
Alkylating agents
RN must verify accuracy of dose
Manipulation/Crushing of pills must be done within a biologic safety cabinet
Give this one a try later!
Oral Chemotherapy
, Wear 1 pair of chemotherapy gloves when handling intact tablets or
capsules
anticancer drugs applied directly to the skin surface
may be used in vulvar cancer with topical 5FU or imiquimod
Give this one a try later!
topical chemotherapy
* Fever and chills occur in majority of patients with first dose
* Consider premedication with acetaminophen and diphenhydramine
* If infusion reaction occurs, patient may need premedication with steroids in future.
* Transient hypotension can occur, hold antihypertensives for 12 hours
Give this one a try later!
Rituximab (Rituxan, monoclonal antibody, chimeric): IV administration with
rate escalation starting at 50 mg/hour
Treatment of certain types of non-Hodgkin's lymphoma, chronic
lymphocytic leukemia (CLL), rheumatoid arthritis
Rituximab works by targeting the CD20 antigen on normal and malignant
B-cells.
Then the body's natural immune defenses are recruited to attack and kill the
marked B-cells.
Stem cells (young cells in the bone marrow that will develop into the
various types of cells) do not have the CD20 antigen. This allows healthy B-
cells to regenerate after treatment.
