Docetaxel (Taxane)
Give this one a try later!
Used to treat Breast/ Lung/ Prostate Cancer
SE: hypersensitivity and anaphylaxis, severe neutropenia, sensory
neuropathy
Considerations: give steroids prior to reduce fluid
retention/hypersensitivity
Busulfan
Give this one a try later!
, Used to treat CML and conditioning for BMT patients
SE: delayed immunosuppression and pulmonary complications, could be
fatal
Considerations: profound myelosuppression (especially if given IV)
Bevacizumab (Avastin)
Give this one a try later!
Used to treat Breast/ Colon/ NSLC
SE: bowel perforation, hemoptysis, hemorrhage, nephrotic syndrome,
hypertension
Idarubicin
Give this one a try later!
An Anthracycline
See Doxorubicin and Daunorubicin for uses and SE
SE: BMD is DLT
Considerations: cardiotoxicity is LESS SEVERE than with Doxorubicin
Etoposide
Give this one a try later!
, Used to treat Testicular/ Lung Cancer, Lymphoma
SE: hypotension, anaphylaxis
Considerations: infuse over at LEAST 30-60 minutes to prevent
bronchospasms, hypotension
Methotrexate
Give this one a try later!
Used to treat CNS Lymphoma, HD and NHD, Leukemia, Lung/ Breast/ Head
& Neck Cancers
SE: Nausea/ vomiting, BMD is uncommon, acute renal tubular necrosis
Considerations: leucovorin is a rescue drug and must be given ON TIME
starting 24hr after completion of Methotrexate, also give bicarb in fluids to
hydrate and alkalinize the urine/bladder
Leucovorin
Give this one a try later!
Potentiates the effect of 5-FU
Antidote for high-dose Methotrexate
SE: pain at injection site, infusion reaction
Considerations: when given with Methotrexate, must be started 24hrs after
completion of Methotrexate
Filgastrim (Neupogen)
Give this one a try later!
Give this one a try later!
Used to treat Breast/ Lung/ Prostate Cancer
SE: hypersensitivity and anaphylaxis, severe neutropenia, sensory
neuropathy
Considerations: give steroids prior to reduce fluid
retention/hypersensitivity
Busulfan
Give this one a try later!
, Used to treat CML and conditioning for BMT patients
SE: delayed immunosuppression and pulmonary complications, could be
fatal
Considerations: profound myelosuppression (especially if given IV)
Bevacizumab (Avastin)
Give this one a try later!
Used to treat Breast/ Colon/ NSLC
SE: bowel perforation, hemoptysis, hemorrhage, nephrotic syndrome,
hypertension
Idarubicin
Give this one a try later!
An Anthracycline
See Doxorubicin and Daunorubicin for uses and SE
SE: BMD is DLT
Considerations: cardiotoxicity is LESS SEVERE than with Doxorubicin
Etoposide
Give this one a try later!
, Used to treat Testicular/ Lung Cancer, Lymphoma
SE: hypotension, anaphylaxis
Considerations: infuse over at LEAST 30-60 minutes to prevent
bronchospasms, hypotension
Methotrexate
Give this one a try later!
Used to treat CNS Lymphoma, HD and NHD, Leukemia, Lung/ Breast/ Head
& Neck Cancers
SE: Nausea/ vomiting, BMD is uncommon, acute renal tubular necrosis
Considerations: leucovorin is a rescue drug and must be given ON TIME
starting 24hr after completion of Methotrexate, also give bicarb in fluids to
hydrate and alkalinize the urine/bladder
Leucovorin
Give this one a try later!
Potentiates the effect of 5-FU
Antidote for high-dose Methotrexate
SE: pain at injection site, infusion reaction
Considerations: when given with Methotrexate, must be started 24hrs after
completion of Methotrexate
Filgastrim (Neupogen)
Give this one a try later!
