Methotrexate clearance is extremely important and something we watch closely. In
patients who are not clearing appropriately and who are experiencing toxicity, what
reversal agent is at our disposal to eliminate methotrexate from the body?
A. Leucovorin
B. Mesna
C. Methylene blue
D. Carboxypeptidase (Glucarpidase)
E. Rasburicase
Give this one a try later!
D. Carboxypeptidase (Glucarpidase)
Which of the following is not a noteworthy toxicity of cytarabine?
A. Flu-like symptoms
,B. Myelosuppression
C. Nephrotoxicity
D. Ocular toxicities
E. Cerebellar toxicities
Give this one a try later!
C. Nephrotoxicity
Which class of chemotherapy agents are the most likely to cause infertility?
A. Taxanes
B. Dihydrofolate reductase inhibitors
C. Pyrimidine analogs
D. Alkylating agents
E. Antitumor antibiotics
Give this one a try later!
D. Alkylating agents
JJ is a 47 year old female who will be starting Carboplatin/Paclitaxel for her newly
diagnosed cancer. Which of the following statement(s) is/are true regarding this
regimen? (Select all that apply)
A. Carboplatin is an alkylating agent that is schedule dependent
B. Paclitaxel requires pre-medications with an H1-antagonist, H2-antagonist and a
corticosteroid
C. Paclitaxel requires PVC-free bags and tubing
D. Paclitaxel is derived from Periwinkle and is considered an antimitotic agent
E. Carboplatin requires pre-medication with dexamethasone
Give this one a try later!
, B. Paclitaxel requires pre-medications with an H1-antagonist, H2-antagonist
and a corticosteroid
C. Paclitaxel requires PVC-free bags and tubing
Which of the following is a potent vesicant that can cause severe damage following
extravasation?
A. Cytarabine
B. Methotrexate
C. Doxorubicin
D. Rituximab
E. Carboplatin
Give this one a try later!
C. Doxorubicin
Which of the following chemotherapy agents is not associated with significant
peripheral neuropathies?
A. Bortezomib
B. Cytarabine
C. Paclitaxel
D. Oxaliplatin
E. Vincristine
Give this one a try later!
B. Cytarabine
patients who are not clearing appropriately and who are experiencing toxicity, what
reversal agent is at our disposal to eliminate methotrexate from the body?
A. Leucovorin
B. Mesna
C. Methylene blue
D. Carboxypeptidase (Glucarpidase)
E. Rasburicase
Give this one a try later!
D. Carboxypeptidase (Glucarpidase)
Which of the following is not a noteworthy toxicity of cytarabine?
A. Flu-like symptoms
,B. Myelosuppression
C. Nephrotoxicity
D. Ocular toxicities
E. Cerebellar toxicities
Give this one a try later!
C. Nephrotoxicity
Which class of chemotherapy agents are the most likely to cause infertility?
A. Taxanes
B. Dihydrofolate reductase inhibitors
C. Pyrimidine analogs
D. Alkylating agents
E. Antitumor antibiotics
Give this one a try later!
D. Alkylating agents
JJ is a 47 year old female who will be starting Carboplatin/Paclitaxel for her newly
diagnosed cancer. Which of the following statement(s) is/are true regarding this
regimen? (Select all that apply)
A. Carboplatin is an alkylating agent that is schedule dependent
B. Paclitaxel requires pre-medications with an H1-antagonist, H2-antagonist and a
corticosteroid
C. Paclitaxel requires PVC-free bags and tubing
D. Paclitaxel is derived from Periwinkle and is considered an antimitotic agent
E. Carboplatin requires pre-medication with dexamethasone
Give this one a try later!
, B. Paclitaxel requires pre-medications with an H1-antagonist, H2-antagonist
and a corticosteroid
C. Paclitaxel requires PVC-free bags and tubing
Which of the following is a potent vesicant that can cause severe damage following
extravasation?
A. Cytarabine
B. Methotrexate
C. Doxorubicin
D. Rituximab
E. Carboplatin
Give this one a try later!
C. Doxorubicin
Which of the following chemotherapy agents is not associated with significant
peripheral neuropathies?
A. Bortezomib
B. Cytarabine
C. Paclitaxel
D. Oxaliplatin
E. Vincristine
Give this one a try later!
B. Cytarabine
