Pharmacology
(3 Version Exams Prep)
(NGN- STYLE QUESTIONS & CASE “SCENARIO S ”)
Answers with detailed Rationale
What You’ll Get:
➢ Each Exam has 60 Pharmacology nursing questions
• PN/LPN focused content
• Exam-style questions
• Answer explanations (rationales)
• Clear, organized format for easy studying
• Printable & digital-friendly
Not affiliated with ATI, VATI or NCLEX. For study purposes only.
,Table of Contents
VATI PN Pharmacology (V1).........................................8
VATI PN Pharmacology (V2).......................................32
VATI PN Pharmacology (V3).......................................58
VATI PN Pharmacology (V1, V2 & V3)
PREVIEW QUESTIONS
14.14 A nurse is reinforcing teaching with a client who is taking rifampin. Which
of the following statements should the nurse make?
A. "Many people who take this medication experience a dry mouth."
B. "Some people who take this medication experience hair loss."
C. "You might urinate more frequently when taking this medication."
D. "You might be unable to wear contact lenses when taking this medication."
Answer: D. "You might be unable to wear contact lenses when taking this
medication."
Rationale: Rifampin causes orange-red discoloration of body fluids (urine, tears, sweat,
saliva). Permanent staining of soft contact lenses occurs. Clients should be warned
about this harmless but alarming effect and advised to use glasses or disposable lenses
during therapy.
15.15 A nurse is administering a varicella immunization to a young adult client
who did not receive the immunization as a child. The client asks the nurse if they
will need additional doses of the vaccine. Which of the following responses
should the nurse make?
A. "You will require a total of three doses about 6 months apart."
B. "You should return for a second dose in 4 to 8 weeks."
C. "You can get a booster dose every 10 years."
D. "You should get another dose in 2 weeks."
Answer: B. "You should return for a second dose in 4 to 8 weeks."
,Rationale: The varicella vaccine series for adults and children ≥13 years requires two
doses: initial dose followed by second dose 4-8 weeks later. This schedule optimizes
seroconversion and long-term immunity against chickenpox infection.
16.16 A nurse is reviewing the medical history of a client who requires ophthalmic
medication to treat glaucoma. Which of the following factors in the client's history
is a contraindication for using beta-adrenergic blocking eye drops to treat this
disorder?
A. Diabetes Mellitus
B. Peptic Ulcer Disease
C. Migraine Headaches
D. Sinus Bradycardia
Answer: D. Sinus Bradycardia
Rationale: Beta-blocker eye drops (timolol, betaxolol) are systemically absorbed and
can exacerbate bradycardia, heart block, or heart failure. Sinus bradycardia (<60 bpm)
is an absolute contraindication due to risk of symptomatic bradycardia or asystole.
1.1 A nurse is reinforcing teaching with a client who is starting phenytoin therapy
to help manage a seizure disorder. Which of the following instructions should the
nurse include?
A. "Take this medication on an empty stomach only."
B. "Brush and floss your teeth after each meal."
C. "Discontinue the medication if you feel dizzy."
D. "Increase your dietary intake of folic acid without consulting your provider."
Answer: B. "Brush and floss your teeth after each meal."
Rationale: Phenytoin causes gingival hyperplasia (gum overgrowth). Meticulous oral
hygiene minimizes this adverse effect. The medication should be taken with food to
reduce GI upset, and folic acid supplementation requires provider supervision as it can
alter phenytoin levels.
2. PHARMACOLOGY TEACHING – LEVOTHYROXINE
, 2.1 A nurse is reinforcing teaching with a client who has a prescription for
levothyroxine to treat hypothyroidism. Which of the following instructions should
the nurse include?
A. "Take your iron supplement at the same time as levothyroxine for better absorption."
B. "Take your iron supplement at least 4 hours from taking levothyroxine."
C. "Take levothyroxine with your morning coffee."
D. "Take levothyroxine at bedtime with a high-fiber snack."
Answer: B. "Take your iron supplement at least 4 hours from taking
levothyroxine."
Rationale: Iron, calcium, and antacids decrease levothyroxine absorption. A 4-hour
separation prevents therapeutic failure. Levothyroxine should be taken on an empty
stomach with water, 30-60 minutes before breakfast.
3. PHARMACOLOGY DATA COLLECTION – METRONIDAZOLE
3.1 A nurse is collecting data from a client who has intestinal amebiasis and is
taking metronidazole. For which of the following findings should the nurse
withhold the metronidazole?
A. Nausea and metallic taste
B. Mild headache
C. Vertigo and ataxia
D. Dark urine
Answer: C. Vertigo and ataxia
Rationale: Vertigo and ataxia indicate central nervous system toxicity requiring
immediate medication discontinuation. Dark urine, metallic taste, and nausea are
expected, non-hazardous adverse effects of metronidazole.
32. Bow-Tie Item – Benzodiazepine Toxicity
32.1 A client receiving midazolam has a blood pressure drop from 122/84 to 86/50
mmHg. Complete the following diagram.
Table