NSG124 / NSG 124 Exam 1
| Latest Update |Newly Released
Pharmacology | Questions & Answers | Graded A+
Guaranteed Pass | 100% Correct - Herzing University
Q1: Which pharmacokinetic phase describes the movement of a drug from the site of
administration into the bloodstream?
A. Distribution
B. Metabolism
C. Absorption
D. Excretion
Correct Answer: C
Rationale: Correct because absorption is defined as the process by which a drug enters the
bloodstream from its site of administration.
Q2: A nurse is preparing to administer an intramuscular (IM) injection. Which action is
essential to ensure patient safety and medication efficacy?
A. Aspirate for 10 seconds to ensure no blood return
B. Us e a 90-degree angle if the adipos e tis s ue is minimal
C. Massage the site vigorously for 5 minutes post-injection
D. Administer the medication in the deltoid regardless of volume
Correct Answer: B
Rationale: Correct because a 90-degree angle is required for IM injections to ensure the
medication reaches the muscle belly, and using the deltoid is appropriate only for small
volumes (usually less than 2 mL).
,Q3: When reviewing a patient's medication list, the nurse identifies that the patient takes
both warfarin (Coumadin) and aspirin. What type of drug interaction is the nurse most
concerned about?
A. Additive effect
B. Synergis tic effect
C. Antagonistic effect
D. Pharmacologic antagonism
Correct Answer: B
Rationale: Correct because the combination of warfarin and aspirin produces a synergistic
effect, significantly increasing the risk of bleeding beyond the simple sum of their individual
effects.
Q4: Which statement best describes the concept of "bioavailability"?
A. The amount of drug metabolized by the liver
B. The percentage of the administered drug dos e that reaches the s ys temic circulation
C. The rate at which a drug is excreted by the kidneys
D. The ability of a drug to bind to plasma proteins
Correct Answer: B
Rationale: Correct because bioavailability refers to the fraction of an administered dose of
unchanged drug that reaches the systemic circulation, indicating the amount available to
produce a therapeutic effect.
Q5: A patient is prescribed a medication classified as a Schedule II controlled substance. What
is a critical nursing implication regarding this prescription?
A. The prescription is valid for 12 months.
B. Refills are permitted up to 5 times within 6 months.
C. The prescription cannot be refilled and requires a new written prescription for each fill.
D. The drug has a low potential for abuse.
, Correct Answer: C
Rationale: Correct because Schedule II drugs have a high potential for abuse, and
prescriptions are not allowed to be refilled; a new prescription is required for each
dispensing.
Q6: Which factor would most likely increase the distribution of a drug to specific body
tissues?
A. High plasma protein binding
B. Increas ed lipid s olubility of the drug
C. Decreased blood flow to the tissue
D. High molecular weight of the drug
Correct Answer: B
Rationale: Correct because lipid-soluble drugs easily cross cell membranes, allowing for wider
distribution into tissues and fat stores compared to water-soluble or large molecules.
Q7: The nurse is reviewing a drug's half-life. If a drug has a half-life of 12 hours, how long will
it take for the drug to reach steady state in the body?
A. 12 hours
B. 24 hours
C. 48 hours
D. 60 hours
Correct Answer: D
Rationale: Correct because it takes approximately four to five half-lives for a drug to reach
steady state concentration; 12 hours x 5 half-lives = 60 hours.
| Latest Update |Newly Released
Pharmacology | Questions & Answers | Graded A+
Guaranteed Pass | 100% Correct - Herzing University
Q1: Which pharmacokinetic phase describes the movement of a drug from the site of
administration into the bloodstream?
A. Distribution
B. Metabolism
C. Absorption
D. Excretion
Correct Answer: C
Rationale: Correct because absorption is defined as the process by which a drug enters the
bloodstream from its site of administration.
Q2: A nurse is preparing to administer an intramuscular (IM) injection. Which action is
essential to ensure patient safety and medication efficacy?
A. Aspirate for 10 seconds to ensure no blood return
B. Us e a 90-degree angle if the adipos e tis s ue is minimal
C. Massage the site vigorously for 5 minutes post-injection
D. Administer the medication in the deltoid regardless of volume
Correct Answer: B
Rationale: Correct because a 90-degree angle is required for IM injections to ensure the
medication reaches the muscle belly, and using the deltoid is appropriate only for small
volumes (usually less than 2 mL).
,Q3: When reviewing a patient's medication list, the nurse identifies that the patient takes
both warfarin (Coumadin) and aspirin. What type of drug interaction is the nurse most
concerned about?
A. Additive effect
B. Synergis tic effect
C. Antagonistic effect
D. Pharmacologic antagonism
Correct Answer: B
Rationale: Correct because the combination of warfarin and aspirin produces a synergistic
effect, significantly increasing the risk of bleeding beyond the simple sum of their individual
effects.
Q4: Which statement best describes the concept of "bioavailability"?
A. The amount of drug metabolized by the liver
B. The percentage of the administered drug dos e that reaches the s ys temic circulation
C. The rate at which a drug is excreted by the kidneys
D. The ability of a drug to bind to plasma proteins
Correct Answer: B
Rationale: Correct because bioavailability refers to the fraction of an administered dose of
unchanged drug that reaches the systemic circulation, indicating the amount available to
produce a therapeutic effect.
Q5: A patient is prescribed a medication classified as a Schedule II controlled substance. What
is a critical nursing implication regarding this prescription?
A. The prescription is valid for 12 months.
B. Refills are permitted up to 5 times within 6 months.
C. The prescription cannot be refilled and requires a new written prescription for each fill.
D. The drug has a low potential for abuse.
, Correct Answer: C
Rationale: Correct because Schedule II drugs have a high potential for abuse, and
prescriptions are not allowed to be refilled; a new prescription is required for each
dispensing.
Q6: Which factor would most likely increase the distribution of a drug to specific body
tissues?
A. High plasma protein binding
B. Increas ed lipid s olubility of the drug
C. Decreased blood flow to the tissue
D. High molecular weight of the drug
Correct Answer: B
Rationale: Correct because lipid-soluble drugs easily cross cell membranes, allowing for wider
distribution into tissues and fat stores compared to water-soluble or large molecules.
Q7: The nurse is reviewing a drug's half-life. If a drug has a half-life of 12 hours, how long will
it take for the drug to reach steady state in the body?
A. 12 hours
B. 24 hours
C. 48 hours
D. 60 hours
Correct Answer: D
Rationale: Correct because it takes approximately four to five half-lives for a drug to reach
steady state concentration; 12 hours x 5 half-lives = 60 hours.
