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HESI RN MEDICAL-SURGICAL V1 EXAM 2026 – 200+ REAL PRACTICE QUESTIONS & ANSWERS | LATEST TEST BANK

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Pass your HESI RN Med-Surg exam with confidence using the most up-to-date 2026 test bank – over 200 real questions covering respiratory, cardiovascular, endocrine, gastrointestinal, renal, neurologic, musculoskeletal, hematologic/oncologic, and infectious diseases. Each question includes correct answers and detailed rationales to boost clinical judgment. No surprises – just what you need to pass. Get exam-ready today!

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Institution
HESI RN MEDICAL-SURGICAL V1
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HESI RN MEDICAL-SURGICAL V1

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HESI RN MedSurg V1 (PDF) | (2026) Nursing Exam

Questions | Medical Surgical

1. A client with COPD has an oxygen saturation of 88%.

Which action should the nurse take first?

A. Increase oxygen to 4 L/min via nasal cannula

B. Encourage deep breathing and coughing

C. Apply a non-rebreather mask at 100% oxygen

D. Auscultate lung sounds

Answer: D

Rationale: Auscultation provides immediate assessment of

breath sounds and guides further intervention. Increasing

oxygen without assessment could suppress hypoxic drive

in COPD.



2. A nurse is caring for a client with a chest tube after

thoracotomy. Which finding requires immediate

intervention?

A. Intermittent bubbling in the suction control chamber

1

,B. Tidaling in the water seal chamber

C. Continuous bubbling in the water seal chamber

D. Drainage of 50 mL in the first hour

Answer: C

Rationale: Continuous bubbling in the water seal chamber

indicates an air leak, which can lead to pneumothorax or

loss of negative pressure. Tidaling is normal; intermittent

bubbling in suction control is expected.



3. Which position is most appropriate for a client with

severe dyspnea from pulmonary edema?

A. Supine

B. Prone

C. High-Fowler’s with legs dependent

D. Trendelenburg

Answer: C

Rationale: High-Fowler’s reduces venous return and allows



2

,gravity to aid lung expansion; legs dependent decreases

preload by pooling blood in lower extremities.



4. A client on mechanical ventilation has a sudden drop in

SpO2 to 82% and high-pressure alarm. What should the

nurse do first?

A. Suction the client

B. Disconnect the client from the ventilator

C. Manually ventilate with a bag-valve mask

D. Increase the FiO2

Answer: C

Rationale: Manual ventilation ensures oxygenation while

troubleshooting the cause (e.g., mucus plug, kinked tube,

or pneumothorax).



5. A client with pneumonia has a fever, productive cough,

and pleuritic chest pain. Which nursing intervention is most

effective to mobilize secretions?

3

, A. Maintain bed rest

B. Administer PRN antitussives

C. Encourage fluid intake to 2–3 L/day

D. Apply oxygen at 2 L/min

Answer: C

Rationale: Adequate hydration thins secretions, making

them easier to expectorate. Antitussives suppress cough

and are avoided when mobilization is needed.



6. A client with tuberculosis is started on isoniazid and

rifampin. Which instruction is most important?

A. Take medications with antacids to prevent GI upset

B. Expect orange discoloration of urine and tears

C. Stop medications when symptoms resolve

D. Avoid foods containing tyramine

Answer: B

Rationale: Rifampin causes harmless orange-red

discoloration of body fluids; clients must be warned to

4

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Institution
HESI RN MEDICAL-SURGICAL V1
Course
HESI RN MEDICAL-SURGICAL V1

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