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HESI RN MEDICAL-SURGICAL V2 EXAM 2026 – 200+ REAL PRACTICE QUESTIONS & ANSWERS | LATEST TEST BANK

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Pass your HESI RN Med-Surg V2 exam with confidence using the most up-to-date 2026 test bank – over 200 real questions covering cardiovascular, respiratory, endocrine, renal, gastrointestinal, neurologic, musculoskeletal, hematologic/oncologic, and infectious disorders. Each question includes correct answers and detailed rationales to sharpen clinical judgment. No surprises – just what you need to pass. Get exam-ready today!

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HESI RN MEDICAL-SURGICAL V2 E
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HESI RN MEDICAL-SURGICAL V2 E

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HESI RN MedSurg V2 (PDF) | (2026) Nursing Exam

Questions | Medical Surgical

1. A client with heart failure is prescribed furosemide 40

mg IV push. Which assessment finding requires immediate

action?

A. Serum potassium 3.8 mEq/L

B. Urine output 30 mL/hour

C. Bilateral crackles in lung bases

D. Blood pressure 90/60 mm Hg

Answer: D

RATIONALE: Hypotension (90/60 mm Hg) indicates

potential hypovolemia or excessive vasodilation.

Furosemide is a loop diuretic that reduces preload; giving

it when BP is already low can cause further hypotension,

leading to decreased organ perfusion (kidneys, brain).

Crackles are expected in heart failure. Potassium 3.8 is

normal. Urine output 30 mL/hour is acceptable.



1

,2. The nurse is caring for a client post-cardiac

catheterization via the femoral artery. The client reports

severe groin pain and a drop in hemoglobin. What is the

priority action?

A. Administer prescribed PRN acetaminophen

B. Assess the groin site for hematoma

C. Apply manual pressure above the insertion site

D. Document the findings

Answer: C

RATIONALE: Severe groin pain plus a drop in hemoglobin

after femoral artery catheterization suggests

retroperitoneal bleeding, a life-threatening complication.

Manual pressure above the insertion site (toward the

abdomen) compresses the femoral artery to control

bleeding. Acetaminophen does not treat bleeding. A

visible hematoma may not be present in retroperitoneal

bleeding.



2

,3. A client with unstable angina is on a heparin drip.

Which laboratory value indicates therapeutic effect?

A. aPTT 60 seconds (control 30 seconds)

B. INR 2.5

C. Platelets 150,000/mm³

D. PT 12 seconds

Answer: A

RATIONALE: For IV unfractionated heparin, the

therapeutic goal is an aPTT of 1.5 to 2.5 times the control

value. Control 30 seconds × 2 = 60 seconds, which is

therapeutic. INR monitors warfarin, not heparin. PT

monitors extrinsic pathway. Platelets assess for

thrombocytopenia, not therapeutic effect.



4. Which client is at highest risk for developing deep vein

thrombosis (DVT)?

A. Postoperative day 1 from knee replacement

B. Client with heart failure on diuretics

3

, C. Young adult with ankle sprain on bed rest

D. Client with pneumonia ambulating with assistance

Answer: A

RATIONALE: Major orthopedic surgery (knee replacement)

plus postoperative immobilization creates Virchow’s triad:

venous stasis, hypercoagulability, and vessel wall

damage. This is the highest DVT risk. Heart failure has

some risk but less than major surgery.



5. A client with COPD has an oxygen saturation of 88%

on 2 L/min nasal cannula. The nurse increases oxygen to

3 L/min. Thirty minutes later, the client is lethargic and

confused. What is the probable cause?

A. Carbon dioxide narcosis

B. Increased intracranial pressure

C. Acute asthma exacerbation

D. Pulmonary embolism



4

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HESI RN MEDICAL-SURGICAL V2 E

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