NCLEX-PN Application Questions
1. A client is prescribed warfarin for atrial fibrillation. Which laboratory value
should the nurse monitor to evaluate therapeutic effect?
A. aPTT
B. INR
C. Platelet count
D. Troponin
2. A client taking an ACE inhibitor reports “puffy” lips and cough. Which action is
most important for the LPN to take?
A. Reassure the client and schedule follow up appointment.
B. Notify the RN.
C. Teach the client that cough is expected.
D. Assess the client’s blood pressure.
3. A client is prescribed benzonatate for cough. Which client statement requires
immediate follow up by the nurse?
A. “I will store it in a child locked cabinet.”
B. “I will swallow the capsule whole.”
C. “I will chew the capsule if my cough is severe.”
D. I will call if my cough lasts more than one week
4. A client has used oxymetazoline nasal spray twice daily for 6 days and reports
worsening congestion. Which action should the nurse take next?
A. Advise the client to increase to every 2 hours for 24 hours
B. Stop the spray and notify the RN.
C. Assess the client’s oral temperature.
D. Call the provider for a second nasal decongestant spray
5. A client taking rifampin reports fatigue and yellowing of the eyes. Which action
should the nurse take first?
A. Document the finding.
B. Review the client’s most recent BUN/Creatinine levels.
C. Teach the client about the side effects of tuberculosis medications.
D. Notify the registered nurse.
,6. A client is prescribed levothyroxine. The client also takes calcium carbonate
daily for reflux. Which client statement indicates a need for further teaching?
A. I will take levothyroxine when I wake up and calcium at lunch
B. I will take levothyroxine with breakfast so my stomach is not upset
C. I will call if I develop chest pain or palpitations
D. I understand it may take several weeks to feel the full effect
7. The nurse is preparing to administer digoxin for a client with heart failure.
Which action should the nurse take first?
A. Review the most recent potassium level
B. Count the apical pulse for one full minute
C. Assess lung sounds for crackles
D. Ask the client whether nausea is present
8. A client is prescribed pseudoephedrine. Which assessment finding is most
important for the nurse to report to the RN before administration?
A. Heart rate 92 bpm
B. Blood pressure 176/98 mmHg
C. Client reports occasional headaches.
D. Oxygen saturation 96% on RA
9. A client is taking prednisone for an autoimmune disorder. Which assessment
finding should the nurse report to the RN immediately?
A. Increased appetite and insomnia.
B. Blood glucose 199mg/dL and increased thirst.
C. Coffee ground emesis.
D. Facial fullness and weight gain of 2 pounds.
10. A client with asthma reports sudden wheezing after ambulating the hall. Which
prescription should the nurse anticipate administering first?
A. Inhaled fluticasone
B. Inhaled salmeterol
C. Inhaled albuterol
D. Oral prednisone
11. A client prescribed an ACE inhibitor for hypertension reports a new dry cough.
Which response by the LPN is best?
A. “Stop the medication today because this is adverse.”
B. “Let me notify the provider for guidance.”
C. “What is your oxygen level?”
D. “Make sure to decrease your sodium intake.”
, 12. A client taking propylthiouracil calls the clinic. Which report should the nurse
address first?
A. Mild headache that started this morning
B. Sore throat with temperature of 100.9 F
C. Reports feeling more tired than usual
D. Weight gain of 2 pounds in 7 days
13. A client is scheduled for radioactive iodine therapy. Which statement requires
follow up by the nurse?
A. I live with my sister and her two young kids.
B. I had a CT scan with contrast two days ago.
C. I am breastfeeding.
D. I have occasional nausea after meals.
14. A client is prescribed apixaban for atrial fibrillation. Which client statement
indicates understanding of the teaching?
A. I will have routine INR checks every week
B. I will not stop this medication without provider guidance
C. I can stop taking my aspirin now
D. I will limit intake of leady greens.
15. A client receiving nebulized acetylcysteine develops wheezing and increased
work of breathing. Which action should the nurse take first?
A. Increase the flow rate to finish the treatment quickly
B. Stop the treatment.
C. Encourage the client to take deep breaths.
D. Place the client in a side-lying position and apply a non-breather mask.
16. A client started levothyroxine 10 days ago. Which assessment finding should
the nurse report to the RN immediately?
A. The client reports feeling less tired in the afternoon
B. The client reports increased sweating and palpitations.
C. The client reports mild constipation
D. The client reports feeling less cold at night
17. A client is prescribed atorvastatin. Which client report should the nurse notify
the RN about immediately?
A. Abdominal discomfort
B. Muscle pain
C. Nausea
D. Increased urine output
1. A client is prescribed warfarin for atrial fibrillation. Which laboratory value
should the nurse monitor to evaluate therapeutic effect?
A. aPTT
B. INR
C. Platelet count
D. Troponin
2. A client taking an ACE inhibitor reports “puffy” lips and cough. Which action is
most important for the LPN to take?
A. Reassure the client and schedule follow up appointment.
B. Notify the RN.
C. Teach the client that cough is expected.
D. Assess the client’s blood pressure.
3. A client is prescribed benzonatate for cough. Which client statement requires
immediate follow up by the nurse?
A. “I will store it in a child locked cabinet.”
B. “I will swallow the capsule whole.”
C. “I will chew the capsule if my cough is severe.”
D. I will call if my cough lasts more than one week
4. A client has used oxymetazoline nasal spray twice daily for 6 days and reports
worsening congestion. Which action should the nurse take next?
A. Advise the client to increase to every 2 hours for 24 hours
B. Stop the spray and notify the RN.
C. Assess the client’s oral temperature.
D. Call the provider for a second nasal decongestant spray
5. A client taking rifampin reports fatigue and yellowing of the eyes. Which action
should the nurse take first?
A. Document the finding.
B. Review the client’s most recent BUN/Creatinine levels.
C. Teach the client about the side effects of tuberculosis medications.
D. Notify the registered nurse.
,6. A client is prescribed levothyroxine. The client also takes calcium carbonate
daily for reflux. Which client statement indicates a need for further teaching?
A. I will take levothyroxine when I wake up and calcium at lunch
B. I will take levothyroxine with breakfast so my stomach is not upset
C. I will call if I develop chest pain or palpitations
D. I understand it may take several weeks to feel the full effect
7. The nurse is preparing to administer digoxin for a client with heart failure.
Which action should the nurse take first?
A. Review the most recent potassium level
B. Count the apical pulse for one full minute
C. Assess lung sounds for crackles
D. Ask the client whether nausea is present
8. A client is prescribed pseudoephedrine. Which assessment finding is most
important for the nurse to report to the RN before administration?
A. Heart rate 92 bpm
B. Blood pressure 176/98 mmHg
C. Client reports occasional headaches.
D. Oxygen saturation 96% on RA
9. A client is taking prednisone for an autoimmune disorder. Which assessment
finding should the nurse report to the RN immediately?
A. Increased appetite and insomnia.
B. Blood glucose 199mg/dL and increased thirst.
C. Coffee ground emesis.
D. Facial fullness and weight gain of 2 pounds.
10. A client with asthma reports sudden wheezing after ambulating the hall. Which
prescription should the nurse anticipate administering first?
A. Inhaled fluticasone
B. Inhaled salmeterol
C. Inhaled albuterol
D. Oral prednisone
11. A client prescribed an ACE inhibitor for hypertension reports a new dry cough.
Which response by the LPN is best?
A. “Stop the medication today because this is adverse.”
B. “Let me notify the provider for guidance.”
C. “What is your oxygen level?”
D. “Make sure to decrease your sodium intake.”
, 12. A client taking propylthiouracil calls the clinic. Which report should the nurse
address first?
A. Mild headache that started this morning
B. Sore throat with temperature of 100.9 F
C. Reports feeling more tired than usual
D. Weight gain of 2 pounds in 7 days
13. A client is scheduled for radioactive iodine therapy. Which statement requires
follow up by the nurse?
A. I live with my sister and her two young kids.
B. I had a CT scan with contrast two days ago.
C. I am breastfeeding.
D. I have occasional nausea after meals.
14. A client is prescribed apixaban for atrial fibrillation. Which client statement
indicates understanding of the teaching?
A. I will have routine INR checks every week
B. I will not stop this medication without provider guidance
C. I can stop taking my aspirin now
D. I will limit intake of leady greens.
15. A client receiving nebulized acetylcysteine develops wheezing and increased
work of breathing. Which action should the nurse take first?
A. Increase the flow rate to finish the treatment quickly
B. Stop the treatment.
C. Encourage the client to take deep breaths.
D. Place the client in a side-lying position and apply a non-breather mask.
16. A client started levothyroxine 10 days ago. Which assessment finding should
the nurse report to the RN immediately?
A. The client reports feeling less tired in the afternoon
B. The client reports increased sweating and palpitations.
C. The client reports mild constipation
D. The client reports feeling less cold at night
17. A client is prescribed atorvastatin. Which client report should the nurse notify
the RN about immediately?
A. Abdominal discomfort
B. Muscle pain
C. Nausea
D. Increased urine output
