All Solved Correct.
What is Niacin associated with? - Answer NAD+, NADH, NADP, NADPH
What is niacin deficiency associated with?
What are the Four D's? - Answer Pellagra
1) Dementia
2) Diarrhea
3) Dermatitis
4) Death
What percent of niacin is bioavailable? - Answer 10%
What are the active forms of niacin? - Answer Nicotinic acid and nicotinamide
What form of niacin is found in animal foods? - Answer - Nicotinamide and nicotinamide
nucleotides
- We don't absorb the nicotinamide nucleotides though
What form of niacin is found in plants? - Answer Nicotinic acid
In a cell, two major forms of niacin are? - Answer 1) NAD+ (oxidized form)
2) NADPH (reduced form)
What does NADH donate? - Answer A hydride ion (a proton with two electrons)
Where is niacin absorbed? - Answer Stomach and small intestines
How is tryptophan involved with niacin? - Answer We use approximately 3% of tryptophan to
form it
, NAD roles? - Answer 1) Glycolysis
2) Oxidative decarboxylation
3) TCA
4) Beta Oxidation
5) Oxidation of ethanol
What form is NADP? - Answer BioSYNTHETIC
(B5) Pantoic acid is linked to ______ via a ______ linkage - Answer Beta-alanine
Peptide
B5 Pantothenic Acid is primarily absorbed in? - Answer Jejunum of small intestine
True of false: High concentrations of B5 can lead to passive diffusion? - Answer True
How is B5 Pantothenic Acid transported when concentration is lower? - Answer The SMVT
transporter aka sodium dependent multivitamin transporter
What are B5 deficiencies associated with? - Answer Burning feet syndrome
What diseases affect B5 absorption? - Answer - Diabetes
- IBD
- These mess with small intenstine and thus vitamin B5 absorption
What does Pantothenic Acid give rise to? - Answer coenzyme A
What is the major rate limiting step? - Answer Pantothenic kinase
What types of environments destroy B5? - Answer Heat, freezing, acidic, alkaline, refining
grain