SECTION A: IMMUNOLOGY (30 Minutes)
INSTRUCTIONS:-
(i) THIS PAPER CONSISTS OF THIRTY (30) MULTIPLE CHOICE
QUESTIONS (MCQs) TO BE ANSWERED IN THIRTY (30) MINUTES.
(ii) EACH MCQ CONSISTS OF A STATEMENT/STEM WHOSE MOST
CORRECT RESPONSE IS PROVIDED AMONG THE FIVE OPTIONS
NUMBERED A TO E.
(iii) FOR EACH MCQ, SELECT ONLY ONE MOST APPROPRIATE OPTION
AND INDICATE BY CIRCLING IT.
EXAMPLE:
Major features of innate immunity include
(a) recognition
(b) specificity
(c) memory
d first line of defense
(e) adaptability
the appropriate response is d
(iv) A CORRECT RESPONSE IN THE MCQs EARNS YOU PLUS ONE (+1)
MARK. AN INCORRECT RESPONSE EARNS YOU MINUS HALF (-½)A
MARK. NO PENALTY FOR UNATTEMPTED MCQ.
(v) ATTEMPT ALL QUESTIONS.
SECTION A: MULTIPLE CHOICE QUESTIONS (MCQs) (3O minutes)
1. Basic immunology involves the understanding of:
(a) Hypersensitivity reactions
(b) Autoimmune diseases
(c) Immunodeficiency disorders
(d) Normal body immune system
(e) Immunopathology
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, Mwaki revision questions
2. Haptens are:
(a) Substances which elicit and react with products of an immune response
(b) Substances which can elicit an immune response if coupled to another
molecule
(c) Substances capable of inducing B cells to produce antibodies without T
cell help
(d) Substances which are processed and expressed by accessory antigen
presenting cells
(e) Part of the T cell antigen receptor
3. Cell-mediated immunity:
(a) Can be transferred passively using immune sera
(b) Is mediated by T cells, macrophages and cytokines
(c) Is not effect against most of the obligate intracellular pathogens
(d) Is mediated by B lymphocytes
(e) Forms part of the innate immunity
4. Plasma cells:
(a) Are the only memory cells of virgin B lymphocytes
(b) Secrete complement factors
(c) Express surface membrane immunoglobulin markers (Smlg)
(d) Are derived from both B and t lumphocytes
(e) Are derived from B lymphocytes and secret immunoglobulins
5. In the Kenya Expanded Programme of Immunization (KEPI) the last vaccine to
be given is against:
(a) Tuberculosis
(b) Measles
(c) Hepatitis
(d) Tetanus
(e) Polio
6. Immunology is not at the forefront of:
(a) Genetically modified (GM) foods
(b) Apprehending hardcore criminals
(c) Prevention of childhood diseases
(d) Human genome research
(e) Replacement of dysfunctional organs
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, Mwaki revision questions
7. Louis Pasteur is credited for:
(a) Cowpox vaccination
(b) Blood group antigens
(c) Complement system proteins
(d) Attenuated vaccines
(e) Opsonins
8. Self-tolerant single positive CD4+ and CD8+ T cells are generated through:
(a) Positive selection
(b) Negative selection
(c) Clonal cell selection
(d) Cortical cell selection
(e) Thymocyte cell selection
9. Antigens are not represented by:
(a) Surface cell components of pathogens
(b) Glycoproteins
(c) Toxins and toxoids
(d) Head shock proteins
(e) Complement system proteins
10. Innate immunity is not associated with:
(a) First line of detance
(b) Phagocytes and NK cells
(c) Cytolines and interferons
(d) Skin as natural barriers
(e) B cells
11. Adaptive immunity does not involve:
(a) Burnet clonal inhibition theory
(b) Extracellular elimination of pathogens
(c) Control of intracellular pathogens
(d) B and T lymphocytes
(e) Recognition, specificity and memory
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