What is the mechanism of action of Naloxone? - Answers Pure opioid antagonist that competes and
displaces opioids receptor sites.
What medications treat opioid disorder? - Answers Methadone;
Buprenorphine, buprenorphine + Naloxone
What medication for opioid use disorder is used with comorbid pain? - Answers Buprenorphine +
Naloxone
Inappropriate use of what substance may be due to uncontrolled pain? - Answers Opioids
What are the Naltrexone delivery methods? - Answers Tablet;
Injectable;
Implant
What is one form of Naltrexone delivery method limited to inpatient use? - Answers Implant
What is the mechanism of action buprenorphine? - Answers Mu receptor partial agonist for opioid
withdrawal
What medication taken too soon after last opioid use increases the chances of intense withdrawal
that comes on very quickly (precipitated withdrawal)? - Answers Buprenorphine
What are symptoms of opioid intoxication? - Answers Nausea and vomiting;
Respiratory depression;
Constipation;
Itching;
Mioisis (small pupil);
Euphoria; and
Sedation
What withdrawal symptoms of opioids? - Answers Nausea and vomiting;
Diarrhea;
Dehydration;
Irritability;
Restlessness;
Yawning;
Twitching;
Increased heart rate and blood pressure;
Chills;
Increased temperature;
Rhinorrhea;
Lacrimation;
Dilated pupils
What medication is given for opioid intoxication during cardiac or respiratory depression is a concern?
- Answers Naloxone
What are symptoms of cocaine intoxication? - Answers Dilated pupils;
Headache;
Tremor;
Hyper-reflexia;
Twitching;
MI;
Nausea and vomiting;
Incontinence/ARF;
Rhabdomyolysis
What is the treatment for cocaine intoxication? - Answers Benzodiazepines;
Antipsychotics;
Management of medical problems that include hypertension, stroke, cardiac arrhythmias,
hyperthermia, and seizures
What would not be the treatment for chest pain and MI from cocaine? - Answers Beta blockers are to
be avoided due to unopposed a-adrenergic stimulation.
What are the symptoms for alcohol intoxication? - Answers Blood levels;
Decreased reaction time;
Muscle incoordination;
, Ataxia;
Dysarthria;
Respiratory failure;
Coma
What are the treatments for severe alcohol intoxication? - Answers Cardiopulmonary function
maintenance;
Thiamine;
Haloperidol PRN for agitation
What medication is given to prevent Wernicke's encephalopathy? - Answers Thiamine given
intramuscular or intravenously along with intravenous fluids and a banana bag
What class of drugs are to be avoided for acute alcohol intoxication? - Answers Benzodiazepines
What is the treatment for uncomplicated alcohol withdrawal? - Answers Benzodiazepines for
symptom triggered or flexed dose.
What kind of half-life do diazepam and chlordiazepoxide have? - Answers Longer half-life
What medications can you give for patients with hepatic dysfunction? - Answers Oxazepam and
lorazepam
What benzodiazepines with a long half-life are used to treat AUD? - Answers Diazepam and
chlordiazepoxide
What benzodiazepines with a moderate half-life are used in AUD patients with liver disease? -
Answers Oxazepam and lorazepam
What are the treatments for alcohol withdrawal symptoms? - Answers Diazepam intravenous;
Lorazepam intravenous or intramuscular;
Thiamine intravenous or intramuscular;
Addressing electrolyte imbalances
What are the treatments for DT? - Answers Acute care management;
Parenteral diazepam or lorazepam;
Thiamine;
Antipsychotics if necessary
What is the mechanism of action of disulfiram? - Answers Via negative reinforcement, where drinking
is avoided due to unpleasant effects.
What is the mechanism of action of Acamprosate? - Answers NMDA receptor antagonist
How is Acamprosate cleared? - Answers Renally
What medication can be given to patients with AUD with hepatic dysfunction? - Answers
Acamprosate
What medication is suitable for AUD with comorbid OUD? - Answers Naltrexone
What medication reduces consumption by decreasing reinforcement properties? - Answers
Naltrexone
What medication only deals with physical dependence, but does not address the psychological
component of smoking? - Answers NRT
What medications are oral stop-smoking aids? - Answers Varenicline;
Bupropion;
Clonidine
"Very Bad Cancer"
What are the "Very Bad Cancer" medications? - Answers Varenicline;
Bupropion;
Clonidine
What medication for smoking cessation treatment should be observed for neuropsychiatric symptoms
that include changes in behavior, hostility, agitation, depressed mood, and suicide-related events that
include ideation, behavior, and attempted suicide? - Answers Bupropion
What is the treatment for cocaine induced chest pain or myocardial infarction? - Answers
Intravenous benzodiazepines
What medications can treat agitation in patients with dementia? - Answers Atypical antipsychotics
What type of medications are used only for short-term and acute episodes of aggression, agitation,
and psychosis in patients with dementia? - Answers Benzodiazepines
What medical emergency can be caused with TCAs, anticholinergics, benzodiazepines, non-
benzodiazepines, corticosteroids, H2 blockers, and opioids in elderly patients? - Answers Delirium