DNP Week 6: Literature Matrix & Translational Research Quiz 2026
|Galen
1. What is the primary purpose of a literature matrix in the DNP project
process?
A. To list all citations in alphabetical order for the reference page
B. To provide a word-for-word transcript of every study reviewed
C. To organize and synthesize research findings to identify gaps and themes
D. To replace the need for a formal literature review paper
Answer: C
Rationale: A literature matrix is a tool used to systematically organize, compare, and
synthesize evidence to identify common themes and gaps in knowledge.
2. Which phase of translational research involves moving laboratory findings
into clinical trials with human subjects?
A. T0
B. T4
C. T3
D. T1
Answer: D
Rationale: T1 research focuses on the transition from basic science (bench) to clinical
application (bedside), typically involving phase 1 clinical trials.
,3. In the hierarchy of evidence, which of the following is considered Level I
evidence?
A. Systematic reviews or meta-analyses of randomized controlled trials (RCTs)
B. Expert opinion of nationally recognized committees
C. Case-control studies
D. Single descriptive or qualitative studies
Answer: A
Rationale: Level I evidence represents the highest level of evidence, such as meta-analyses
or systematic reviews of all relevant RCTs.
4. Which column in a literature matrix helps determine the ‘strength’ of the
evidence presented by a study?
A. Level of Evidence/Design
B. Year of Publication
C. Theoretical Framework
D. Sample Size
Answer: A
Rationale: The Level of Evidence or Study Design column allows the practitioner to
evaluate the rigor and reliability of the study’s conclusions.
5. What is the main focus of ‘T2’ translational research?
A. Basic science discovery
B. Translation to practice (effectiveness research)
C. Translation to patients (clinical efficacy trials)
D. Translation to communities and global health
Answer: C
Rationale: T2 research translates findings from clinical trials into evidence-based
guidelines and tests efficacy in a controlled environment.
, 6. Which of the following is a hallmark of ‘synthesis’ rather than ‘summary’?
A. Describing one study at a time in chronological order
B. Discussing how multiple articles support or contradict a specific theme
C. Reiterating the abstract of each article
D. Listing the names of all authors for every study
Answer: B
Rationale: Synthesis involves integrating various sources to show patterns, contradictions,
and consensus across the body of literature.
7. The ‘P’ in a PICOT question stands for Population. Why is this critical when
building a matrix?
A. To identify which software to use for data analysis
B. To determine how much the project will cost
C. To ensure the articles selected are relevant to the specific group being studied
D. To define the publication date of the articles
Answer: C
Rationale: Defining the population ensures that the evidence gathered is applicable to the
target demographic of the DNP project.
8. What does ‘T3’ translational research specifically target?
A. Laboratory bench work
B. Implementation of evidence into real-world clinical practice
C. Initial human safety trials
D. Epidemiological studies on a global scale
Answer: B
Rationale: T3 research focuses on implementation science—moving evidence-based
interventions into routine clinical care.
|Galen
1. What is the primary purpose of a literature matrix in the DNP project
process?
A. To list all citations in alphabetical order for the reference page
B. To provide a word-for-word transcript of every study reviewed
C. To organize and synthesize research findings to identify gaps and themes
D. To replace the need for a formal literature review paper
Answer: C
Rationale: A literature matrix is a tool used to systematically organize, compare, and
synthesize evidence to identify common themes and gaps in knowledge.
2. Which phase of translational research involves moving laboratory findings
into clinical trials with human subjects?
A. T0
B. T4
C. T3
D. T1
Answer: D
Rationale: T1 research focuses on the transition from basic science (bench) to clinical
application (bedside), typically involving phase 1 clinical trials.
,3. In the hierarchy of evidence, which of the following is considered Level I
evidence?
A. Systematic reviews or meta-analyses of randomized controlled trials (RCTs)
B. Expert opinion of nationally recognized committees
C. Case-control studies
D. Single descriptive or qualitative studies
Answer: A
Rationale: Level I evidence represents the highest level of evidence, such as meta-analyses
or systematic reviews of all relevant RCTs.
4. Which column in a literature matrix helps determine the ‘strength’ of the
evidence presented by a study?
A. Level of Evidence/Design
B. Year of Publication
C. Theoretical Framework
D. Sample Size
Answer: A
Rationale: The Level of Evidence or Study Design column allows the practitioner to
evaluate the rigor and reliability of the study’s conclusions.
5. What is the main focus of ‘T2’ translational research?
A. Basic science discovery
B. Translation to practice (effectiveness research)
C. Translation to patients (clinical efficacy trials)
D. Translation to communities and global health
Answer: C
Rationale: T2 research translates findings from clinical trials into evidence-based
guidelines and tests efficacy in a controlled environment.
, 6. Which of the following is a hallmark of ‘synthesis’ rather than ‘summary’?
A. Describing one study at a time in chronological order
B. Discussing how multiple articles support or contradict a specific theme
C. Reiterating the abstract of each article
D. Listing the names of all authors for every study
Answer: B
Rationale: Synthesis involves integrating various sources to show patterns, contradictions,
and consensus across the body of literature.
7. The ‘P’ in a PICOT question stands for Population. Why is this critical when
building a matrix?
A. To identify which software to use for data analysis
B. To determine how much the project will cost
C. To ensure the articles selected are relevant to the specific group being studied
D. To define the publication date of the articles
Answer: C
Rationale: Defining the population ensures that the evidence gathered is applicable to the
target demographic of the DNP project.
8. What does ‘T3’ translational research specifically target?
A. Laboratory bench work
B. Implementation of evidence into real-world clinical practice
C. Initial human safety trials
D. Epidemiological studies on a global scale
Answer: B
Rationale: T3 research focuses on implementation science—moving evidence-based
interventions into routine clinical care.
