NR 565 - advanced pharmacology FINAL - Chamberlain EXAM
1. In which patient population is Metformin contraindicated in?
A. Diabetics with HA1c < 7.0%
B. Patients older than 50
C. Alcoholics
D. Women suffering from infertility: C. Alcoholics
2. What lab value suggests metformin might be contraindicated?
A. eGFR <30
B. Crea 0.8
C. WBC 7.8
D. Bun 17: A. eGFR <30
3. What medication is contraindicated to treat diabetes if a patient already has a cardiac
ejection fraction rate of 40%?
A. Second Generation sulfonyureas
B. Thiazolidinediones
C. Dopamine Agonist
D. Glucosidase Inhibitor: B. Thiazolidinediones
4. Sabrina is a 35-year-old female who presents with complaints of fatigue, anxiety, and
palpitations. She has a long history of obesity and reports that she is happy that she has
lost 23 pounds in the last 2 months. She also reports that she has trouble sleeping and
her husband complains that she is keeping the house too cold. Physical exam reveals slight
tachycardia at 104 bpm and a slightly enlarged thyroid. Thyroid testing reveals
hyperthyroidism or Grave's disease.
Which of the following agents is the first-line treatment for hyperthyroidism or Grave's
disease?
A. Methimazole
B. Metoprolol
C. Allopurinol
D. Levothyroxine: A. Methimazole
,NR 565 - advanced pharmacology FINAL - Chamberlain EXAM
5.Which of the following medications would be considered the first line of treatment for
a newly diagnosed Diabetic patient with adequate renal and hepatic function?
A: NovoLog Sliding Scale Insulin
B: Liraglutide (Victoza)
C: Oral Metformin
D: Glipizide: C: Oral Metformin
6.Of the following medications, which is most likely to cause hypoglycemia?
A. Metformin
B. Insulin
C. Incretin mimetics
D. Thiazolidinediones: B. Insulin
7. Which symptoms are most expected of a patient diagnosed with hypothyroidism?
A. shortness of breath, wheezing, fatigue
B. tachycardia, insomnia, weight loss, goiter
C. irritability, anxiety, dizziness, increased sweating
D. dry pale skin, brittle hair, fatigue, myxedema:
D. dry skin, brittle hair, fatigue, myxedema
8. Patients with an increased risk for UTIs and genital infections or an active diagnosis,
should avoid what drug class/es for treatment of Type II Diabetes?
A. Thiazolidinediones (Glitazones)
B. Biguanide.
C. Sodium-Glucose Cotransporter 2 (SGLT-2) Inhibitors.
D. All of the above.: C. Sodium-Glucose Cotransporter 2 (SGLT-2) Inhibitors.
9. A 45-year-old patient with a history of type 2 diabetes presents to the clinic for a
follow-up appointment. The healthcare provider has prescribed metformin as part of
the treatment plan. Which of the following statements regarding metformin is correct?
, NR 565 - advanced pharmacology FINAL - Chamberlain EXAM
A. Metformin primarily stimulates insulin production from the pancreas.
B. Metformin reduces glucose levels primarily by decreasing insulin resis-tance.
C. Metformin is associated with a risk of hypoglycemia.
D. Metformin improves insulin sensitivity and reduces hepatic glucose pro-duction.:
D. Metformin improves insulin sensitivity and reduces hepatic glucose production.
10. In what part of the body are SGLT-2 (sodium-glucose cotransporter 2) inhibitors
active?
A. Small intestine
B. Pancreas
C. Renal tubules
D. Stomach: C. Renal tubules
11. Which of the following statements is not true regarding sulfonylureas?
A. Sulonlyreas are safe to prescribe to pregnant and/or breast-feeding women.
B. Patients should be educated about signs and symptoms of hypoglycemia.
C. Sulfonylureas cause a dose-dependent reduction in blood glucose.
D. Sulfonylureas are indicated for only patients diagnosed with type 2 dia-betes.:
A. Sulonlyreas are safe to prescribe to pregnant and/or breast-feeding women.
12. A 33 year old woman previously diagnosed with hyperthyroidism noted have
tachycardia. Which medication should the NP add to the patients regimen?
A. atenolol
B. levothyroxine
C. lithium
D. semaglutide: A. atenolol
13. Once a patient's thyroid is euthyroid and their dose can be maintained at the
prescription, at what interval should their TSH be re-checked?
A. every 18 months
B. every 12 months
C. every 6 months
1. In which patient population is Metformin contraindicated in?
A. Diabetics with HA1c < 7.0%
B. Patients older than 50
C. Alcoholics
D. Women suffering from infertility: C. Alcoholics
2. What lab value suggests metformin might be contraindicated?
A. eGFR <30
B. Crea 0.8
C. WBC 7.8
D. Bun 17: A. eGFR <30
3. What medication is contraindicated to treat diabetes if a patient already has a cardiac
ejection fraction rate of 40%?
A. Second Generation sulfonyureas
B. Thiazolidinediones
C. Dopamine Agonist
D. Glucosidase Inhibitor: B. Thiazolidinediones
4. Sabrina is a 35-year-old female who presents with complaints of fatigue, anxiety, and
palpitations. She has a long history of obesity and reports that she is happy that she has
lost 23 pounds in the last 2 months. She also reports that she has trouble sleeping and
her husband complains that she is keeping the house too cold. Physical exam reveals slight
tachycardia at 104 bpm and a slightly enlarged thyroid. Thyroid testing reveals
hyperthyroidism or Grave's disease.
Which of the following agents is the first-line treatment for hyperthyroidism or Grave's
disease?
A. Methimazole
B. Metoprolol
C. Allopurinol
D. Levothyroxine: A. Methimazole
,NR 565 - advanced pharmacology FINAL - Chamberlain EXAM
5.Which of the following medications would be considered the first line of treatment for
a newly diagnosed Diabetic patient with adequate renal and hepatic function?
A: NovoLog Sliding Scale Insulin
B: Liraglutide (Victoza)
C: Oral Metformin
D: Glipizide: C: Oral Metformin
6.Of the following medications, which is most likely to cause hypoglycemia?
A. Metformin
B. Insulin
C. Incretin mimetics
D. Thiazolidinediones: B. Insulin
7. Which symptoms are most expected of a patient diagnosed with hypothyroidism?
A. shortness of breath, wheezing, fatigue
B. tachycardia, insomnia, weight loss, goiter
C. irritability, anxiety, dizziness, increased sweating
D. dry pale skin, brittle hair, fatigue, myxedema:
D. dry skin, brittle hair, fatigue, myxedema
8. Patients with an increased risk for UTIs and genital infections or an active diagnosis,
should avoid what drug class/es for treatment of Type II Diabetes?
A. Thiazolidinediones (Glitazones)
B. Biguanide.
C. Sodium-Glucose Cotransporter 2 (SGLT-2) Inhibitors.
D. All of the above.: C. Sodium-Glucose Cotransporter 2 (SGLT-2) Inhibitors.
9. A 45-year-old patient with a history of type 2 diabetes presents to the clinic for a
follow-up appointment. The healthcare provider has prescribed metformin as part of
the treatment plan. Which of the following statements regarding metformin is correct?
, NR 565 - advanced pharmacology FINAL - Chamberlain EXAM
A. Metformin primarily stimulates insulin production from the pancreas.
B. Metformin reduces glucose levels primarily by decreasing insulin resis-tance.
C. Metformin is associated with a risk of hypoglycemia.
D. Metformin improves insulin sensitivity and reduces hepatic glucose pro-duction.:
D. Metformin improves insulin sensitivity and reduces hepatic glucose production.
10. In what part of the body are SGLT-2 (sodium-glucose cotransporter 2) inhibitors
active?
A. Small intestine
B. Pancreas
C. Renal tubules
D. Stomach: C. Renal tubules
11. Which of the following statements is not true regarding sulfonylureas?
A. Sulonlyreas are safe to prescribe to pregnant and/or breast-feeding women.
B. Patients should be educated about signs and symptoms of hypoglycemia.
C. Sulfonylureas cause a dose-dependent reduction in blood glucose.
D. Sulfonylureas are indicated for only patients diagnosed with type 2 dia-betes.:
A. Sulonlyreas are safe to prescribe to pregnant and/or breast-feeding women.
12. A 33 year old woman previously diagnosed with hyperthyroidism noted have
tachycardia. Which medication should the NP add to the patients regimen?
A. atenolol
B. levothyroxine
C. lithium
D. semaglutide: A. atenolol
13. Once a patient's thyroid is euthyroid and their dose can be maintained at the
prescription, at what interval should their TSH be re-checked?
A. every 18 months
B. every 12 months
C. every 6 months
