Nagelhout Pharm 2 Test 2 EXAM (2025)
QUESTIONS AND (elaborated) WITH
COMPLETE SOLUTIONS
Enzymes for metabolism of catecholemines - ANSWER-COMT
MAO
Post synaptic neurotransmitter sympathetic - ANSWER-NE
Interference with synthesis of transmitter - ANSWER-sympatholytic - choline
acetyl transferase inhibitors
metabolic transformation by same pathway as precursor of transmitter - ANSWER-
sympatholytic - methyldopa
blockade of transport system at nerve terminal membrane - ANSWER-
sympathomimetic - cocaine
Blockade of transport system of storage vesicle - ANSWER-sympatholytic -
reserpine, vesamicol
, promotion of exocytosis or displacement of transmitter from axonal terminal -
ANSWER-sympathomimetic - amphetammine, tyramine
prevention of release of transmitter - ANSWER-sympatholytic - botulinim toxin,
clonidine, dexmedetomidine
mimicry of transmitter at postjunctional sites - ANSWER-sympathomimetic -
dobutamine, terbutaline, albuterol, isoproterenol, methacholine, bethanachol,
nicotine,
blockade of post synaptic receptor - ANSWER-sympatholytic - Atropine,
atracurium, -amines, -osin, -olol
inhibition of enzymatic breakdown of transmitter - ANSWER-sympathomimetic -
MAO inhibitors, COMT inhibitors, AChE inhibitors
interference with second messenger system - ANSWER-sympathomimetic -
milrinone
choline acetyl transferase inhibitors - ANSWER-sympatholytic
a-methyl tyrosine - ANSWER-sympatholytic
methyldopa - ANSWER-sympatholytic
QUESTIONS AND (elaborated) WITH
COMPLETE SOLUTIONS
Enzymes for metabolism of catecholemines - ANSWER-COMT
MAO
Post synaptic neurotransmitter sympathetic - ANSWER-NE
Interference with synthesis of transmitter - ANSWER-sympatholytic - choline
acetyl transferase inhibitors
metabolic transformation by same pathway as precursor of transmitter - ANSWER-
sympatholytic - methyldopa
blockade of transport system at nerve terminal membrane - ANSWER-
sympathomimetic - cocaine
Blockade of transport system of storage vesicle - ANSWER-sympatholytic -
reserpine, vesamicol
, promotion of exocytosis or displacement of transmitter from axonal terminal -
ANSWER-sympathomimetic - amphetammine, tyramine
prevention of release of transmitter - ANSWER-sympatholytic - botulinim toxin,
clonidine, dexmedetomidine
mimicry of transmitter at postjunctional sites - ANSWER-sympathomimetic -
dobutamine, terbutaline, albuterol, isoproterenol, methacholine, bethanachol,
nicotine,
blockade of post synaptic receptor - ANSWER-sympatholytic - Atropine,
atracurium, -amines, -osin, -olol
inhibition of enzymatic breakdown of transmitter - ANSWER-sympathomimetic -
MAO inhibitors, COMT inhibitors, AChE inhibitors
interference with second messenger system - ANSWER-sympathomimetic -
milrinone
choline acetyl transferase inhibitors - ANSWER-sympatholytic
a-methyl tyrosine - ANSWER-sympatholytic
methyldopa - ANSWER-sympatholytic
