CORRECT ANSWERS COMPLETE
HEMATOLOGY STUDY GUIDE
●● What leukemia would lymphoblast be associated with?
Answer: ALL (Blasts = Acute)
●● What leukemia would myeloblasts be associated with?
Answer: AML (Blasts = Acute)
●● What gene mutation is associated with polycythemia vera?
Answer: JAK2 mutation
●● TTP symptom Mnemonic: FAT-RN. What dose FAT-RN stand for?
Answer: Fever - Anemia - Thrombocytopenia - Renal failure -
Neurologic involvement
●● List two conditions which predispose a patient to antiphospholipid
syndrome.
Answer: Systemic Lupus Erythematosus - Women with recurrent
abortions
,●● What disorder is a hemoglobin electrophoresis result of "SA"
indicative of?
Answer: Sickle cell trait
●● What disorder is a hemoglobin electrophoresis result of "SS"
indicative of?
Answer: Sickle cell disease
●● What type of anemia are cephalosporins PCN NSAIDS methyldopa
associated with?
Answer: Immune hemolytic anemia
●● Erythropoietin analogs should be suspended once the hemoglobin is
>_____?
Answer: 11 mg/dl
●● Erythropoietin analogs should only be initiated if the hemoglobin is
< ____?
Answer: 10 mg/dl
●● What two types of anemia have macroovalocytes?
Answer: B12 and folate deficiency
, ●● Which anemia has a decreased MCV, decreased MCH
(hypochromic) yet normal TIBC and ferritin?
Answer: Thalassemia
●● Acute chest syndrome occurs during the acute phase of which
anemia?
Answer: Hemolytic sickle cell crisis
●● What are some common oxidative events which may trigger
hemolysis in G6PD deficiency?
Answer: Antimalarials - Sulfa drugs - Aspirin - Febrile Illness - Acidosis
- Fava beans
●● What type of anemia does a + osmotic fragility test indicate?
Answer: Hereditary Spherocytosis
●● What do an increased LDH, decreased Haptoglobin and an increased
indirect Bilirubin represent?
Answer: Hemolysis
●● What type of anemia does a + direct coombs indicate?
Answer: Autoimmune hemolytic anemia