ASCP BOC ACTUAL STUDY EXAMS GUIDE
QUESTIONS AND ANSWERS SURE A+
✔✔In order to prepare 100 mL of 15 mg/dL BUN working standard from a stock
standard containing 500 mg/dL of urea nitrogen, the number of mL of stock solution that
should be used is:
a. 3 mL
b. 5 mL
c. 33 mL
d. 75 mL - ✔✔a. 3 mL
✔✔A patient with glomerulonephritis is most likely to present with the following serum
results:
a. creatinine decreased
b. calcium increased
c. phosphorus decreased
d. BUN increased - ✔✔d. BUN increased
✔✔The principle excretory form of nitrogen is:
a. amino acids
,b. creatinine
c. urea
d. uric acid - ✔✔c. urea
✔✔In the Jaffe reaction, creatinine reacts with:
a. alkaline sulfasalazine solution to produce an orange-yellow complex
b. potassium iodide to form a reddish-purple complex
c. sodium nitroferricyanide to yield a reddish-brown color
d. alkaline picrate solution to yield an orange-red complex - ✔✔d. alkaline picrate
solution to yield an orange-red complex
✔✔Creatinine clearance is used to estimate the:
a. tubular secretion of creatinine
b. glomerular secretion of creatinine
c. renal glomerular and tubular mass
d. glomerular filtration rate - ✔✔d. glomerular filtration rate
✔✔A blood creatinine value of 5.0 mg/dL is most likely to be found with which of the
following blood values:
a. osmolality: 292 mOsm/kg
b. uric acid: 8 mg/dL
c. urea nitrogen: 80 mg/dL
d. ammonia: 80 ug/dL - ✔✔c. urea nitrogen: 80 mg/dL
✔✔Technical problems encountered during the collection of an amniotic fluid specimen
caused doubt as to whether the specimen was amniotic in origin. Which 1 of the
following procedures would best establish that the fluid is amniotic in origin?
a. measurement of absorbance at 450 nm
b. creatinine measurement
c. lecithin/sphingomyelin ratio
d. human amniotic placental lactogen (HPL) - ✔✔b. creatinine measurement
✔✔Which of the following represents the end product of purine metabolism in humans?
a. AMP and GMP
b. DNA and RNA
c. allantoin
d. uric acid - ✔✔d. uric acid
✔✔Which of the following substances is the biologically active precursor of a fat soluble
vitamin?
,a. biotin
b. retinol
c. folic acid
d. ascrobic acid - ✔✔b. retinol
✔✔The troponin complex consists of:
a. troponin T, calcium and tropomyosin
b. troponin C, troponin I and troponin T
c. troponin I, actin and tropomyosin
d. troponin C, myoglobin, and actin - ✔✔b. troponin C, troponin I, troponin T
✔✔The presence of C-reactive protein in the blood is an indication of:
a. a recent streptococcal infection
b. recovery from a pneumococcal infeciton
c. an inflammatory process
d. a state of hypersensitivity - ✔✔c. an inflammatory process
✔✔Oligoclonal bands are present on electrophoresis of concentrated CSF and also on
concurrently tested serum of the same patient. The proper interpretation is:
a. diagnostic for primary CNS tumor
b. diagnostic for multiple sclerosis
c. CNS involvement by acute leukemia
d. nondiagnostic for multiple sclerosis - ✔✔d. nondiagnostic for multiple sclerosis
✔✔Which of the following is an example of a peptide bond? - ✔✔b
✔✔90% of the copper present in adult blood is bound to:
a. transferrin
b. ceruloplasmin
c. albumin
d. cryoglobulin - ✔✔b. ceruloplasmin
✔✔Which of the following determinations is useful in prenatal diagnosis of open neural
tube defects?
a. amniotic fluid alpha-fetoprotein
b. amniotic fluid estradiol
c. maternal serum estradiol
d. maternal serum estrone - ✔✔a. amniotic fluid alpha-fetoprotein
, ✔✔Below are the results of a protein electrophoresis:
These results are consistent with a(n):
a. normal serum protein pattern
b. normal CSF protein pattern
c. abnormal serum protein pattern
d. abnormal CSF protein pattern - ✔✔b. normal CSF protein pattern
✔✔Serum concentrations of vitamin B12 are elevated in:
a. pernicious anemia relapse
b. patients on chronic hemodialysis
c. chronic granulocytic leukemia
d. Hodgkin disease - ✔✔c. chronic granulocytic leukemia
✔✔Absorption of vitamin B12 requires the presence of:
a. intrinsic factor
b. gastin
c. secretin
d. folic acid - ✔✔a. intrinsic factor
✔✔The procedure used to determine the presence of neural tube defects is:
a. lecithin/sphingomyelin ratio
b. amniotic fluid creatinine
c. measurement of absorbance at 450 nm
d. alpha-fetoprotein - ✔✔d. alpha-fetoprotein
✔✔Following overnight fasting, hypoglycemia in adults is defined as a glucose of:
a. ≤ 70 mg/dL (≤ 3.9 mmol/L)
b. ≤ 60 mg/dL (≤ 3.3 mmol/L)
c. ≤ 55 mg/dL (≤ 3.0 mmol/L)
d. ≤ 45 mg/dL (≤ 2.5 mmol/L) - ✔✔d. ≤ 45 mg/dL (≤ 2.5 mmol/L)
✔✔The following results are from a 21-year-old patient with with a back injury who
appears otherwise healthy:
Whole blood glucose: 77 mg/dL (4.2 mmol/L)
Serum glucose: 88 mg/dL (4.8 mmol/L)
CSF glucose: 56 mg/dL (3.1 mmol/L)
The best interpretation of these results is that:
a. the whole blood and serum values are expected but the CSF value is elevated
QUESTIONS AND ANSWERS SURE A+
✔✔In order to prepare 100 mL of 15 mg/dL BUN working standard from a stock
standard containing 500 mg/dL of urea nitrogen, the number of mL of stock solution that
should be used is:
a. 3 mL
b. 5 mL
c. 33 mL
d. 75 mL - ✔✔a. 3 mL
✔✔A patient with glomerulonephritis is most likely to present with the following serum
results:
a. creatinine decreased
b. calcium increased
c. phosphorus decreased
d. BUN increased - ✔✔d. BUN increased
✔✔The principle excretory form of nitrogen is:
a. amino acids
,b. creatinine
c. urea
d. uric acid - ✔✔c. urea
✔✔In the Jaffe reaction, creatinine reacts with:
a. alkaline sulfasalazine solution to produce an orange-yellow complex
b. potassium iodide to form a reddish-purple complex
c. sodium nitroferricyanide to yield a reddish-brown color
d. alkaline picrate solution to yield an orange-red complex - ✔✔d. alkaline picrate
solution to yield an orange-red complex
✔✔Creatinine clearance is used to estimate the:
a. tubular secretion of creatinine
b. glomerular secretion of creatinine
c. renal glomerular and tubular mass
d. glomerular filtration rate - ✔✔d. glomerular filtration rate
✔✔A blood creatinine value of 5.0 mg/dL is most likely to be found with which of the
following blood values:
a. osmolality: 292 mOsm/kg
b. uric acid: 8 mg/dL
c. urea nitrogen: 80 mg/dL
d. ammonia: 80 ug/dL - ✔✔c. urea nitrogen: 80 mg/dL
✔✔Technical problems encountered during the collection of an amniotic fluid specimen
caused doubt as to whether the specimen was amniotic in origin. Which 1 of the
following procedures would best establish that the fluid is amniotic in origin?
a. measurement of absorbance at 450 nm
b. creatinine measurement
c. lecithin/sphingomyelin ratio
d. human amniotic placental lactogen (HPL) - ✔✔b. creatinine measurement
✔✔Which of the following represents the end product of purine metabolism in humans?
a. AMP and GMP
b. DNA and RNA
c. allantoin
d. uric acid - ✔✔d. uric acid
✔✔Which of the following substances is the biologically active precursor of a fat soluble
vitamin?
,a. biotin
b. retinol
c. folic acid
d. ascrobic acid - ✔✔b. retinol
✔✔The troponin complex consists of:
a. troponin T, calcium and tropomyosin
b. troponin C, troponin I and troponin T
c. troponin I, actin and tropomyosin
d. troponin C, myoglobin, and actin - ✔✔b. troponin C, troponin I, troponin T
✔✔The presence of C-reactive protein in the blood is an indication of:
a. a recent streptococcal infection
b. recovery from a pneumococcal infeciton
c. an inflammatory process
d. a state of hypersensitivity - ✔✔c. an inflammatory process
✔✔Oligoclonal bands are present on electrophoresis of concentrated CSF and also on
concurrently tested serum of the same patient. The proper interpretation is:
a. diagnostic for primary CNS tumor
b. diagnostic for multiple sclerosis
c. CNS involvement by acute leukemia
d. nondiagnostic for multiple sclerosis - ✔✔d. nondiagnostic for multiple sclerosis
✔✔Which of the following is an example of a peptide bond? - ✔✔b
✔✔90% of the copper present in adult blood is bound to:
a. transferrin
b. ceruloplasmin
c. albumin
d. cryoglobulin - ✔✔b. ceruloplasmin
✔✔Which of the following determinations is useful in prenatal diagnosis of open neural
tube defects?
a. amniotic fluid alpha-fetoprotein
b. amniotic fluid estradiol
c. maternal serum estradiol
d. maternal serum estrone - ✔✔a. amniotic fluid alpha-fetoprotein
, ✔✔Below are the results of a protein electrophoresis:
These results are consistent with a(n):
a. normal serum protein pattern
b. normal CSF protein pattern
c. abnormal serum protein pattern
d. abnormal CSF protein pattern - ✔✔b. normal CSF protein pattern
✔✔Serum concentrations of vitamin B12 are elevated in:
a. pernicious anemia relapse
b. patients on chronic hemodialysis
c. chronic granulocytic leukemia
d. Hodgkin disease - ✔✔c. chronic granulocytic leukemia
✔✔Absorption of vitamin B12 requires the presence of:
a. intrinsic factor
b. gastin
c. secretin
d. folic acid - ✔✔a. intrinsic factor
✔✔The procedure used to determine the presence of neural tube defects is:
a. lecithin/sphingomyelin ratio
b. amniotic fluid creatinine
c. measurement of absorbance at 450 nm
d. alpha-fetoprotein - ✔✔d. alpha-fetoprotein
✔✔Following overnight fasting, hypoglycemia in adults is defined as a glucose of:
a. ≤ 70 mg/dL (≤ 3.9 mmol/L)
b. ≤ 60 mg/dL (≤ 3.3 mmol/L)
c. ≤ 55 mg/dL (≤ 3.0 mmol/L)
d. ≤ 45 mg/dL (≤ 2.5 mmol/L) - ✔✔d. ≤ 45 mg/dL (≤ 2.5 mmol/L)
✔✔The following results are from a 21-year-old patient with with a back injury who
appears otherwise healthy:
Whole blood glucose: 77 mg/dL (4.2 mmol/L)
Serum glucose: 88 mg/dL (4.8 mmol/L)
CSF glucose: 56 mg/dL (3.1 mmol/L)
The best interpretation of these results is that:
a. the whole blood and serum values are expected but the CSF value is elevated
