CU CHAMBERLAIN UNIVERSITY
1 TINU
EST. 1889 College of Nursing & Health Professions
MN 553: Advanced Pharmacology
UNIT 1 QUIZ — RATIONAL PRESCRIBING, DRUG REGULATION, PHARMACOGENOMICS &
MONITORING
INSTITUTION PROGRAM
Chamberlain University MSN — Family Nurse Practitioner
COURSE CODE COURSE TITLE
MN 553 Advanced Pharmacology
ACADEMIC YEAR EXAM TITLE
2025–2026 Unit 1 Quiz — Prescribing Principles & Pharmacogenomics
TOTAL QUESTIONS EXAM FORMAT
55 Multiple Choice — Select the Single Best Answer
General Instructions
▸ Read each question carefully before selecting your answer.
▸ Select the single best answer for each multiple-choice item.
▸ This Unit 1 quiz covers rational drug selection and the WHO prescribing model, therapeutic drug monitoring,
drug scheduling (DEA Controlled Substances), electronic health records, pharmacogenetics and
pharmacogenomics, CYP450 enzyme polymorphisms, and pharmacoeconomic analysis types.
▸ All questions are weighted equally unless otherwise noted.
▸ Electronic devices, notes, and reference materials are prohibited during the examination.
Q MULTIPLE CHOICE QUESTIONS 55 Questions
,1. Rational drug selection means patients receive medications that are:
A. The newest and most expensive on the market
B. Appropriate to their clinical needs, in doses meeting individual requirements, for an adequate period, at the
lowest cost
C. Always brand-name to ensure quality
D. Selected based on pharmaceutical representative recommendations
CORRECT ANSWER:
B. Appropriate to their clinical needs, in doses meeting individual requirements, for an adequate
period, at the lowest cost
RATIONALE:
Rational drug selection, as defined by the World Health Organization, requires that patients receive medications
appropriate to their clinical needs, in doses that meet their individual requirements, for an adequate period of
time, and at the lowest cost to them and their community. This encompasses efficacy, safety, appropriateness,
and cost-effectiveness. Options A, C, and D violate these principles.
2. The WHO model of prescribing includes which sequence of steps?
A. Diagnose, treat, monitor, educate
B. Accurate diagnosis, specify therapeutic objective, choose treatment, start treatment, educate patient, monitor
effectiveness
C. Choose drug, write prescription, dispense, follow up
D. Assess, plan, implement, evaluate
CORRECT ANSWER:
B. Accurate diagnosis, specify therapeutic objective, choose treatment, start treatment, educate
patient, monitor effectiveness
RATIONALE:
The WHO six-step model for rational prescribing is: (1) Accurate diagnosis, (2) Specify therapeutic objective, (3)
Choose treatment, (4) Start treatment, (5) Educate patient, and (6) Monitor effectiveness. The mnemonic "I Can
PresCribe A Drug" represents: Indication, Contraindications, Precautions, Cost/Compliance, Efficacy, Adverse
effects, Dose/Duration/Direction.
, 3. Passive monitoring of drug therapy involves:
A. Scheduling follow-up examinations to determine effectiveness
B. Educating the patient on expected outcomes and instructing them to contact the provider if treatment is
ineffective or adverse effects occur
C. Drawing regular serum drug levels
D. Performing weekly physical examinations
CORRECT ANSWER:
B. Educating the patient on expected outcomes and instructing them to contact the provider if
treatment is ineffective or adverse effects occur
RATIONALE:
Passive monitoring relies on patient education — the patient is taught what to expect from therapy and
instructed to contact the provider if the treatment is not effective or adverse effects occur. Active monitoring (A)
is when the provider schedules follow-up examinations to determine effectiveness. Options C and D describe
specific active monitoring methods.
4. Active monitoring of drug therapy is when:
A. The patient self-monitors at home
B. The provider schedules follow-up examination to determine effectiveness
C. The pharmacist monitors for drug interactions
D. No monitoring is required
CORRECT ANSWER:
B. The provider schedules follow-up examination to determine effectiveness
RATIONALE:
Active monitoring is provider-initiated — the provider schedules a follow-up examination specifically to
determine the effectiveness of drug therapy. This may include physical assessment, laboratory testing, or other
diagnostic procedures. Passive monitoring (A) relies on patient reporting. Active monitoring is essential for
drugs with narrow therapeutic indexes.
1 TINU
EST. 1889 College of Nursing & Health Professions
MN 553: Advanced Pharmacology
UNIT 1 QUIZ — RATIONAL PRESCRIBING, DRUG REGULATION, PHARMACOGENOMICS &
MONITORING
INSTITUTION PROGRAM
Chamberlain University MSN — Family Nurse Practitioner
COURSE CODE COURSE TITLE
MN 553 Advanced Pharmacology
ACADEMIC YEAR EXAM TITLE
2025–2026 Unit 1 Quiz — Prescribing Principles & Pharmacogenomics
TOTAL QUESTIONS EXAM FORMAT
55 Multiple Choice — Select the Single Best Answer
General Instructions
▸ Read each question carefully before selecting your answer.
▸ Select the single best answer for each multiple-choice item.
▸ This Unit 1 quiz covers rational drug selection and the WHO prescribing model, therapeutic drug monitoring,
drug scheduling (DEA Controlled Substances), electronic health records, pharmacogenetics and
pharmacogenomics, CYP450 enzyme polymorphisms, and pharmacoeconomic analysis types.
▸ All questions are weighted equally unless otherwise noted.
▸ Electronic devices, notes, and reference materials are prohibited during the examination.
Q MULTIPLE CHOICE QUESTIONS 55 Questions
,1. Rational drug selection means patients receive medications that are:
A. The newest and most expensive on the market
B. Appropriate to their clinical needs, in doses meeting individual requirements, for an adequate period, at the
lowest cost
C. Always brand-name to ensure quality
D. Selected based on pharmaceutical representative recommendations
CORRECT ANSWER:
B. Appropriate to their clinical needs, in doses meeting individual requirements, for an adequate
period, at the lowest cost
RATIONALE:
Rational drug selection, as defined by the World Health Organization, requires that patients receive medications
appropriate to their clinical needs, in doses that meet their individual requirements, for an adequate period of
time, and at the lowest cost to them and their community. This encompasses efficacy, safety, appropriateness,
and cost-effectiveness. Options A, C, and D violate these principles.
2. The WHO model of prescribing includes which sequence of steps?
A. Diagnose, treat, monitor, educate
B. Accurate diagnosis, specify therapeutic objective, choose treatment, start treatment, educate patient, monitor
effectiveness
C. Choose drug, write prescription, dispense, follow up
D. Assess, plan, implement, evaluate
CORRECT ANSWER:
B. Accurate diagnosis, specify therapeutic objective, choose treatment, start treatment, educate
patient, monitor effectiveness
RATIONALE:
The WHO six-step model for rational prescribing is: (1) Accurate diagnosis, (2) Specify therapeutic objective, (3)
Choose treatment, (4) Start treatment, (5) Educate patient, and (6) Monitor effectiveness. The mnemonic "I Can
PresCribe A Drug" represents: Indication, Contraindications, Precautions, Cost/Compliance, Efficacy, Adverse
effects, Dose/Duration/Direction.
, 3. Passive monitoring of drug therapy involves:
A. Scheduling follow-up examinations to determine effectiveness
B. Educating the patient on expected outcomes and instructing them to contact the provider if treatment is
ineffective or adverse effects occur
C. Drawing regular serum drug levels
D. Performing weekly physical examinations
CORRECT ANSWER:
B. Educating the patient on expected outcomes and instructing them to contact the provider if
treatment is ineffective or adverse effects occur
RATIONALE:
Passive monitoring relies on patient education — the patient is taught what to expect from therapy and
instructed to contact the provider if the treatment is not effective or adverse effects occur. Active monitoring (A)
is when the provider schedules follow-up examinations to determine effectiveness. Options C and D describe
specific active monitoring methods.
4. Active monitoring of drug therapy is when:
A. The patient self-monitors at home
B. The provider schedules follow-up examination to determine effectiveness
C. The pharmacist monitors for drug interactions
D. No monitoring is required
CORRECT ANSWER:
B. The provider schedules follow-up examination to determine effectiveness
RATIONALE:
Active monitoring is provider-initiated — the provider schedules a follow-up examination specifically to
determine the effectiveness of drug therapy. This may include physical assessment, laboratory testing, or other
diagnostic procedures. Passive monitoring (A) relies on patient reporting. Active monitoring is essential for
drugs with narrow therapeutic indexes.
