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NR 325 Exam 1 EDAPT Questions and Answers 2026 | 350+ Practice Questions with Rationales | Endocrine Disorders, Diabetes Mellitus, Renal Disorders, Dialysis, Glaucoma, Cataracts & Hearing Disorders | Chamberlain University

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This comprehensive NR 325 Exam 1 EDAPT Study Guide contains more than 350 NCLEX-style questions, detailed answers, clinical scenarios, and application-based rationales covering the most heavily tested concepts in Adult Health II nursing. Developed for Chamberlain University NR 325 students, this resource consolidates high-yield EDAPT content related to endocrine disorders, diabetes mellitus, urinary and renal disorders, chronic kidney disease, dialysis management, ophthalmologic conditions, and hearing disorders. The material is specifically designed to strengthen clinical judgment, prioritization, nursing interventions, pharmacology, diagnostic interpretation, and exam readiness for nursing students preparing for major course examinations. The endocrine nursing section provides extensive review of hypothyroidism, hyperthyroidism, thyroid storm, myxedema coma, Cushing’s syndrome, diabetes insipidus, pituitary disorders, hormone regulation, thyroidectomy complications, endocrine diagnostics, and endocrine pharmacology. Students learn to interpret thyroid function tests, identify disease-specific manifestations, recognize endocrine emergencies, and implement evidence-based nursing interventions for clients experiencing hormonal imbalances. High-priority concepts such as levothyroxine therapy, thyroid-stimulating hormone (TSH) monitoring, calcium management following thyroidectomy, and management of thyroid crises are emphasized throughout the review. A major focus of this guide is diabetes mellitus management, including insulin physiology, glucose regulation, diabetes diagnosis, hemoglobin A1C interpretation, insulin administration techniques, oral antidiabetic medications, diabetic ketoacidosis (DKA), hyperosmolar hyperglycemic syndrome (HHS), nutrition therapy, exercise recommendations, hypoglycemia treatment, and long-term complication prevention. The material includes numerous patient-care scenarios that reinforce safe medication administration, insulin mixing procedures, emergency management, and patient education essential for contemporary nursing practice. The renal and urinary elimination section thoroughly reviews acute kidney injury (AKI), chronic kidney disease (CKD), nephrolithiasis, pyelonephritis, urinary diagnostics, electrolyte disturbances, acid-base imbalances, dialysis therapy, vascular access management, and renal replacement therapies. Students gain detailed knowledge of kidney function assessment, glomerular filtration rate (GFR), blood urea nitrogen (BUN), creatinine interpretation, dialysis complications, fluid management, hyperkalemia treatment, and nursing care priorities for clients experiencing renal dysfunction. Special emphasis is placed on critical care scenarios involving fluid overload, electrolyte emergencies, and dialysis access complications. Additional content focuses on ophthalmologic and sensory disorders, including glaucoma, cataracts, visual acuity testing, postoperative eye surgery care, medication administration for ocular conditions, hearing assessment, Weber and Rinne testing, Meniere’s disease, sensorineural hearing loss, conductive hearing loss, vertigo management, and ototoxic medications. Students review disease manifestations, pharmacologic treatments, patient education, safety considerations, and preventive health measures commonly tested on nursing examinations. The content aligns closely with evidence-based concepts presented in leading nursing references including Lewis's Medical-Surgical Nursing, Brunner & Suddarth's Textbook of Medical-Surgical Nursing, and Medical-Surgical Nursing. The material reinforces core competencies in endocrine regulation, diabetes management, renal pathophysiology, dialysis nursing, ophthalmologic care, and sensory system assessment while promoting safe clinical decision-making and patient-centered nursing practice. This study guide is particularly valuable for students preparing for NR 325 Exam 1, Adult Health II examinations, ATI Medical-Surgical Nursing assessments, HESI specialty examinations, NCLEX-RN preparation, and comprehensive medical-surgical nursing reviews. The structured question-and-answer format encourages active recall, improves retention of high-yield concepts, strengthens test-taking strategies, and helps learners identify knowledge gaps before high-stakes nursing examinations. Relevant for: Chamberlain University Nursing Students NR 325 Adult Health II Students Medical-Surgical Nursing Students BSN Students ADN Students Practical Nursing Students Endocrine Nursing Students Diabetes Care Students Renal Nursing Students Dialysis Nursing Students Ophthalmology Nursing Students Sensory Disorders Nursing Students ATI Medical-Surgical Preparation Students HESI Preparation Students NCLEX-RN Candidates Clinical Nursing Students Keywords: NR 325 exam 1, NR325 EDAPT, adult health 2, endocrine disorders, hypothyroidism, hyperthyroidism, thyroid storm, myxedema coma, thyroidectomy, thyroid cancer, thyroid function tests, TSH, thyroxine, diabetes insipidus, Cushing syndrome, endocrine pharmacology, hormone regulation, diabetes mellitus, type 1 diabetes, type 2 diabetes, insulin therapy, insulin administration, insulin mixing, hemoglobin A1C, blood glucose monitoring, diabetic ketoacidosis, DKA, hyperosmolar hyperglycemic syndrome, HHS, hypoglycemia, hyperglycemia, metformin, oral antidiabetic medications, diabetes complications, renal disorders, urinary elimination, acute kidney injury, AKI, chronic kidney disease, CKD, nephrolithiasis, pyelonephritis, dialysis, hemodialysis, peritoneal dialysis, arteriovenous fistula, electrolyte imbalances, hyperkalemia, hypocalcemia, metabolic acidosis, glomerular filtration rate, GFR, blood urea nitrogen, BUN, creatinine, fluid balance, glaucoma, cataracts, visual acuity testing, Snellen chart, ocular medications, timolol, pilocarpine, hearing disorders, Meniere disease, vertigo, Weber test, Rinne test, conductive hearing loss, sensorineural hearing loss, ototoxic medications, nursing exam questions, nursing study guide, ATI preparation, HESI review, NCLEX preparation, Chamberlain University

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NR 325 Exam 1 Edapts 2026
Exam All Answers and
Illustrations Given



The nurse is caring for a client with fluid volume deficit. Which hormone

is most likely affecting fluid balance?




Thyroid stimulating hormone (TSH)

Antidiuretic hormone (ADH)

Growth hormone (GH)

,Luteinizing hormone (LH) - ANSWER ✔✔Antidiuretic hormone (ADH)


The nurse is caring for a client with extreme tachycardia, diarrhea,

weight loss, hypertension, and intolerance to heat. Which hormone is

most likely affecting the client's metabolic rate?




Adrenocorticotropic hormone (ACTH)

Somatostatin

Melanocyte-stimulating hormone (MSH)


Triiodothyronine (T3) - ANSWER ✔✔Triiodothyronine (T3)


For each endocrine disorder, specify its likely manifestations.




Cushing's Disease

Diabetes Insipidus

Hypothyroidism




Delayed wound healing

Brittle hair and nails

Polyuria

,Hypertension

Polydipsia


Constipation - ANSWER ✔✔Cushing's Disease


Delayed wound healing

Hypertension




Diabetes Insipidus

Polyuria

Polydipsia




Hypothyroidism

Brittle hair and nails

Constipation

The nurse is caring for a client who is prescribed an MRI with contrast to

evaluate the pituitary gland. Which lab value must the nurse review

before testing can occur?




Platelet count

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, Magnesium level

Creatinine level


Glucose level - ANSWER ✔✔Creatinine level


Jodie Calhoun (pronouns: she/her/hers), age 35, presents to the

emergency department (ED) with reports of chronic fatigue and muscle

weakness as well as hair loss, constipation, and a weight gain of 15

pounds in the past 6 weeks. Assessment reveals facial and eyelid

edema and dry skin.




Vital signs are T 97.2 °F (36.2 °C), P 52, BP 115/65, and RR 16.




Question

The nurse suspects alterations of which hormones? Select all that apply.

Insulin

Thyroid-stimulating hormone (TSH)

Epinephrine

Glucagon

Thyroxine

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