NR341 PHARMACOLOGY CJE BENCHMARK TEST BANK, ALL TOPICS FULLY COVERED| QUESTIONS AND ANSWERS WITH VERIFIED SOLUTIONS AND DETAILED RATIONALES GRADE A NCLEX STUDY GUIDE| 2026 UPDATE.

NR341 PHARMACOLOGY CJE BENCHMARK TEST BANK, ALL TOPICS FULLY COVERED|

QUESTIONS AND ANSWERS WITH VERIFIED SOLUTIONS AND DETAILED RATIONALES GRADE

A NCLEX STUDY GUIDE| 2026 UPDATE.




1. Which statement best describes the mechanism of action of beta blockers?
A. They block calcium channels to reduce myocardial contractility.
B. They block beta-adrenergic receptors, decreasing heart rate and contractility.
C. They inhibit angiotensin-converting enẒyme, reducing vasoconstriction.
D. They increase sodium excretion by blocking reabsorption in the loop of Henle.
✓ Correct Answer: B. They block beta-adrenergic receptors, decreasing heart rate and
⬛
contractility.
Rationale: Beta blockers (e.g., metoprolol, propranolol) act as beta-adrenergic antagonists,
preventing epinephrine and norepinephrine from binding to β1 receptors in the heart. This lowers
heart rate, myocardial contractility, and blood pressure, reducing cardiac workload.

2. What is the primary mechanism of action for ACE inhibitors such as lisinopril?
A. Block angiotensin II receptors, preventing vasoconstriction.
B. Inhibit conversion of angiotensin I to angiotensin II, promoting vasodilation.
C. Decrease cardiac output by slowing AV node conduction.
D. Increase calcium influx into vascular smooth muscle.
✓ Correct Answer: B. Inhibit conversion of angiotensin I to angiotensin II, promoting
⬛
vasodilation.
Rationale: ACE inhibitors block the enẒyme that converts angiotensin I to angiotensin II, a
powerful vasoconstrictor. This results in vasodilation, decreased blood pressure, and reduced
aldosterone secretion. Adverse effects include cough, hyperkalemia, and angioedema.


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