OBJECTIVE
ASSESSMENT (OA)
ADVANCED PATHOPHYSIOLOGY
QUESTIONS AND VERIFIED ANSWERS|
100% CORRECT| GRADED A+
EXAM COVER SHEET
PROGRAM: NR (Nursing Program)
COURSE NUMBER: WGU D115
COURSE NAME: ADVANCED PATHOPHYSIOLOGY
EXAM NAME: EXAM STUDY GUIDE
ADVANCED PATHOPHYSIOLOGY
,Conductive Hearing Loss Mechanism
Question
A patient presents to the clinic with difficulty hearing in one ear after a recent upper
respiratory infection. The patient reports muffled sounds and a feeling of fullness in the
ear. Diagnostic consideration includes blockage of the ear canal, fluid accumulation
behind the tympanic membrane, or dysfunction of the ossicles. The nurse reviews cranial
nerve involvement and anatomy of hearing. Which structure is primarily associated with
conductive hearing loss?
A. Inner ear
B. Middle ear
C. 5th cranial nerve
D. 8th cranial nerve
Correct Answer: B. Middle ear
Neonatal Innate Immunity Deficiency
Question
A 30-day-old infant is admitted to the emergency department with fever, decreased oral
intake, and reduced urine output. A full septic workup is initiated, including blood
cultures, urine cultures, lumbar puncture, and chest imaging. The APRN considers
immature components of neonatal innate immunity that increase infection risk. Which
immune factor is most likely deficient in this neonate?
A. Dysfunctional chemotactic factor response
,B. Excess collectin and collectin-like protein
C. Relative deficiency of factor B
D. High levels of mannose
Correct Answer: C. Relative deficiency of factor B
Hereditary Angioedema Pathophysiology
Question
A 12-year-old African American patient presents with recurrent, painless swelling of the
eye and lower lip that occurs spontaneously and resolves over several days. There is no
associated rash, fever, or respiratory distress. Laboratory studies suggest hyperactivation
of plasma protein systems involved in inflammation. The APRN suspects hereditary
angioedema. Which deficiency is most associated with this condition?
A. Plasminogen
B. Bradykinin
C. C1 esterase inhibitor
D. Hageman factor
Correct Answer: C. C1 esterase inhibitor
Recurrent Infections in Down Syndrome
Question
, A child diagnosed with Down syndrome has experienced recurrent respiratory infections
since birth. The parent expresses concern about the frequency of illness and asks for an
explanation. The APRN considers contributing physiological factors that increase
aspiration risk and infection susceptibility. What is the most likely underlying cause?
A. Hyperthyroidism increases infection risk
B. Gastroesophageal reflux disease causes aspiration of thin fluids
C. Short stature causes poor lung development
D. Hypertonia causes airway restriction
Correct Answer: B. Gastroesophageal reflux disease causes aspiration of thin fluids
Stress Response and Metabolic Effect
Question
A 36-year-old patient presents with symptoms of depression following a major life
change. The patient reports weight gain, reduced activity levels, and difficulty sleeping.
The APRN educates the patient on physiologic effects of chronic stress on the body,
including metabolic changes. Which effect is most associated with chronic stress
response?
A. Increased protein synthesis
B. Increased smooth muscle contraction
C. Decreased glucose uptake
D. Increased immune activation