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WGU D115 OBJECTIVE ASSESSMENT (OA) ADVANCED PATHOPHYSIOLOGY LATEST UPDATE (2026/2027) QUESTIONS AND VERIFIED ANSWERS | 100% CORRECT | GRADED A+

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WGU D115 OBJECTIVE ASSESSMENT (OA) ADVANCED PATHOPHYSIOLOGY LATEST UPDATE (2026/2027) QUESTIONS AND VERIFIED ANSWERS | 100% CORRECT | GRADED A+

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WGU D115
OBJECTIVE
ASSESSMENT (OA)
ADVANCED PATHOPHYSIOLOGY

QUESTIONS AND VERIFIED ANSWERS|
100% CORRECT| GRADED A+

EXAM COVER SHEET
PROGRAM: NR (Nursing Program)

COURSE NUMBER: WGU D115

COURSE NAME: ADVANCED PATHOPHYSIOLOGY

EXAM NAME: EXAM STUDY GUIDE

ADVANCED PATHOPHYSIOLOGY

,Conductive Hearing Loss Mechanism

Question



A patient presents to the clinic with difficulty hearing in one ear after a recent upper
respiratory infection. The patient reports muffled sounds and a feeling of fullness in the
ear. Diagnostic consideration includes blockage of the ear canal, fluid accumulation
behind the tympanic membrane, or dysfunction of the ossicles. The nurse reviews cranial
nerve involvement and anatomy of hearing. Which structure is primarily associated with
conductive hearing loss?



A. Inner ear

B. Middle ear

C. 5th cranial nerve

D. 8th cranial nerve



Correct Answer: B. Middle ear



Neonatal Innate Immunity Deficiency

Question



A 30-day-old infant is admitted to the emergency department with fever, decreased oral
intake, and reduced urine output. A full septic workup is initiated, including blood
cultures, urine cultures, lumbar puncture, and chest imaging. The APRN considers
immature components of neonatal innate immunity that increase infection risk. Which
immune factor is most likely deficient in this neonate?



A. Dysfunctional chemotactic factor response

,B. Excess collectin and collectin-like protein

C. Relative deficiency of factor B

D. High levels of mannose



Correct Answer: C. Relative deficiency of factor B



Hereditary Angioedema Pathophysiology

Question



A 12-year-old African American patient presents with recurrent, painless swelling of the
eye and lower lip that occurs spontaneously and resolves over several days. There is no
associated rash, fever, or respiratory distress. Laboratory studies suggest hyperactivation
of plasma protein systems involved in inflammation. The APRN suspects hereditary
angioedema. Which deficiency is most associated with this condition?



A. Plasminogen

B. Bradykinin

C. C1 esterase inhibitor

D. Hageman factor



Correct Answer: C. C1 esterase inhibitor



Recurrent Infections in Down Syndrome

Question

, A child diagnosed with Down syndrome has experienced recurrent respiratory infections
since birth. The parent expresses concern about the frequency of illness and asks for an
explanation. The APRN considers contributing physiological factors that increase
aspiration risk and infection susceptibility. What is the most likely underlying cause?



A. Hyperthyroidism increases infection risk

B. Gastroesophageal reflux disease causes aspiration of thin fluids

C. Short stature causes poor lung development

D. Hypertonia causes airway restriction



Correct Answer: B. Gastroesophageal reflux disease causes aspiration of thin fluids



Stress Response and Metabolic Effect

Question



A 36-year-old patient presents with symptoms of depression following a major life
change. The patient reports weight gain, reduced activity levels, and difficulty sleeping.
The APRN educates the patient on physiologic effects of chronic stress on the body,
including metabolic changes. Which effect is most associated with chronic stress
response?



A. Increased protein synthesis

B. Increased smooth muscle contraction

C. Decreased glucose uptake

D. Increased immune activation

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