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Biol 2116 Microbiology - Chapter 1 to 6 Summary for MICRO Exam with Complete Solution | New 2026/27 Update

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Biol 2116 Microbiology - Chapter 1 & 6 Summary for MICRO Exam with Complete Solution | New 2026/27 Update explores the microbial world, detailing the characteristics of microorganisms, their roles in health and disease, and historical perspectives on microbiology. It covers essential concepts such as cell theory, types of microbes, and the impact of pathogens on human health, alongside significant historical figures and their contributions to the field

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Biol 2116
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Biol 2116

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lOMoAR cPSD| 6861666




Biol 2116 Microbiology - Chapter 1 & 6
Summary for MICRO Exam with Complete
Solution | New 2026/27 Update


Chapter 1: Living in a Microbial World

- Vast majority of living things are microorganisms (bacteria, viruses, fungi &
protozoa—too small to see with human eye)

- Microorganisms are frequently called microbes
- Some microbes are pathogenic- causing infection and disease and food spoilage

- Fundamental principle in biology is cell theory
→ that all living things are composed of cells
→ cells are the basic unit of life
→ all living things are composed of one or more cells

- Microorganisms are most commonly unicellular (consist of 1 cell)

- Microbes are multicellular - Cells fall into two types:

1. Prokaryotic
▪ simpler and small cells
▪ not surrounded by a nuclear membrane
▪ most commonly bacteria and archea

2. Eukaryotic
▪ larger and more complex cells
▪ membrane surrounding the genetic material forms the nucleus ▪
eukaryotic cells have a variety of other small structures called
organelles (little organs that carry out specific functions of the
cell)
▪ protozoa, fungi and algae
▪ internal parasites called ‘helminths’ are flukes, tapeworms, round
worms

- All living cells have an internal environment that is different than their
surroundings
→ cells have mechanisms to maintain these differences through homeostasis

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- All living things have the ability to reproduce, which requires a blueprint, usually
encoded in a molecule called deoxyribonucleic acid (DNA)

- Living things can respond to their environment, can alter behaviour as
environmental conditions change

- Metabolism: ability to assimilate and use energy

- Evolution: characteristics of living things may change over many generations
(all

life changes over time)

Microbiology: Study of several distinct groups of living things
- Bacteria are small, most commonly single celled, prokaryotic organisms

- Other major groups of prokaryotes are archea

- Eukaryotic microorganisms include fungi and protozoa

- Viruses are the ultimate parasite- unable to reproduce unless they gain access to
the interior of an appropriate cell
→ once inside they hijack cell
→ cell forced to divert energy and other resources to viral replication
→ virus will continue to replicate until cell dies

- Viruses consist of little more than genetic material surrounded by a protein coat

- Examples of viruses include: influenza and HIV

- Pronions are infectious proteins that cause neurological disorders
→ example: mad cow disease

Microbiology is a science

- The bacteria pseudomonas stutzeri
→ restore artwork
→ digest common pollutants in artwork

- Hypothesis: a tentative explanation for a specific question that must be testable

- to test a hypothesis- must use a valid experiment
▪ an experimental group
→ the crucial factor will be manipulated
▪ a control group

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→ the crucial factor will be left unchanged

- the larger the number of treatments/experiments, the more meaningful the
results

- if a hypothesis cannot be disproved, it may become a theory

- a theory is an important principle supported by a large body of experimental
evidence


Chapter 6: The Microbiology of History and the History of Microbiology

- Scarlet fever is caused by gram + bacterium: Streptococcus pyogenes

- The fall of Rome
▪ part of the cause was a decrease in population
▪ population decline partially caused by disease
▪ problem especially bad in agriculture area where mosquitos thrived

- Mosquitos are other arthropods that transmit pathogens between humans are
known as vectors

- Diseases that vectors transmit are called vector-borne diseases. Examples
include malaria, plague

- 540- the Bubonic Plague broke out in North Africa
▪ quickly spread to the rest of the world
▪ now known as ‘Plague of Justinian’ may have been worst epidemic in human
history

- Bubonic plague descriptions
▪ high fever
▪ swollen glands (buboes) in armpit and groins
▪ buboes rupture, resulting in gangrenous lesions and causing excruciating pain ▪
death often within a week


- Plague is another example of vector-borne disease
▪ fleas are the vectors (host)


- Pandemic is a worldwide epidemic

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- An acute disease: pathogen replicates rapidly and symptoms disappear quickly.
Examples: smallpox, measles
▪ two outcomes: host recovers or dies
▪ if host recovers, will become immune to the same pathogen
▪ often called “crowd diseases”


- Chronic disease can last indefinitely, sometimes for years or decades.
Examples: tuberculosis
▪ host is able to control but not eliminate the disease- causing microorganism


- When the immune system is confronted with a particular pathogen- proteins
called antibodies are produced that react with and neutralize the microorganism

- Antibodies are very specific—each type of antibody binds to only one type of
microbe


- Occasionally antibodies will bind to a second microbe- this antibody is then said
to be cross-reactive


- Some infectious diseases are caused by microorganisms


- Humans are vulnerable to infection with a variety of much larger parasitic worms
known as helminths


- A parasite is any organism, microscopic or not, that lives in or on another
organism.
▪ getting a place to live, reproduce and obtain nutrients


- 1647: Anton vanLeeuwenhoek was the first to describe microoganisms:
discovered bacteria and protozoa


- 1859: Louis Pasteur: discredited the notion of spontaneous generation
▪ was also making important contributions to the science of winemaking
▪ discovered fermentation
▪ realized he could eliminate these bacteria by temporarily heating the wine
▪ process known now as pasteurization

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