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Definition
✅ Antidote: N-Acetylcysteine (NAC) (Mucomyst, Acetadote)
Replenishes glutathione stor
Most effective if given within
Administered orally (Mucomy
✅ Other Supportive Treatment
Activated Charcoal (If inges
tract)
IV Fluids (Correct hypotension
Dextrose Infusion (If hypogl
Vitamin K or Fresh Frozen Pl e coagulopathy)
Liver Transplant (For irreversibl ere cases)
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, Treatment for Large AAAs (> 5.5 Cm)
Labs for Acetaminophen Overdose
or Symptomatic
Treatment for Acetaminophen
Treatment for Small AAA (< 5.5 Cm)
Overdose
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Term
Key Signs of Distributive Shock in Liver Failure:
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🧠 Altered mental status (confusion, lethargy, disorientation)
✋ Asterixis (flapping hand tremor when wrists extended)
💤 Lethargy progressing to coma (in severe cases)
◻ Risk of cerebral edema (especially in acute liver failure)
📉 Elevated ammonia levels (due to failure of hepatic detoxification)
🚨 Severe hepatic encephalopathy can lead to cerebral edema, herniation, and
death.
📉 Hypotension despite adequate fluid volume
💓 Tachycardia (compensatory response)💦 Edema, ascites due to capillary
leak
Coagulopathy (bleeding risk)
Lactic acidosis due to poor organ perfusion
, 📈 AST/ALT ↑↑↑ (can exceed 10,000 IU/L)📉 Low platelets (thrombocytopenia)
🩸 Prolonged PT/INR (INR >1.5 = liver failure)
⚠ Increased ammonia (hepatic encephalopathy risk)
📉 Hypoglycemia (liver stores glycogen, failure = low sugar)
🟡 Increased bilirubin (jaundice)
✅ Surgical Repair Options:
· Endovascular Aneurysm Repair (EVAR) (Preferred, less invasive, stent graft
placement)
Open Aneurysm Repair (OAR) (Surgical graft placement, longer recovery, used for
rupture cases)
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Definition
✔ NPO (Nothing by Mouth) → Rest the pancreas, prevent enzyme
stimulation
✔ IV Fluids (Aggressive hydration with Lactated Ringer's or Normal
Saline)
✔ Pain Control (IV opioids: Morphine, Fentanyl, Hydromorphone)
✔ NG Tube (for severe vomiting, paralytic ileus)
✔ Electrolyte Replacement (Monitor for hypocalcemia, hypokalemia)
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Key Points for Pancreatitis Pancreatitis Supportive Care
, Treatment for small AAA (< 5.5 cm) Medications for Pancreatitis
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Definition
· Hematocrit & Hemoglobin (H&H): ↓ If rupture causes internal
bleeding
· BUN & Creatinine: Monitor kidney function pre/post-surgery
· D-dimer: May be elevated in thrombus formation
· Lipid Panel: Assesses atherosclerosis risk
Coagulation Panel (PT/INR, aPTT, Platelets): Monitor if anticoagulation
is needed pre-surgery
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Treatment for Large AAAs (> 5.5 Cm)
Labs for AAA
or Symptomatic
Labs for Acetaminophen Overdose Treatment for Small AAA (< 5.5 Cm)
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Definition