AND ANSWERS SURE A+
✔✔MAOs adverse effects-6 - ✔✔Hypertensive crisis, diet restriction, avoid meds, five
week after Prozac, two week after other antidepressants, no other medications for two
weeks after discontinuing
✔✔MAOs diet restriction-4 compounds - ✔✔Tyrosine, high tyramine, tryptophan,
phenylalanine
✔✔Tyrosine foods-10 - ✔✔Aged cheese, aged wine, fava or broad bean pods,
sauerkraut, soy sauce, tap or draft beer, overripe fruit, cured meat, spoiled food
✔✔MAOs drugs to avoid- 6 - ✔✔Antidepressants, Dextromethorphan, stimulants,
sympathomimetics, meperidine, disulfiram
✔✔MAOs side effects 11 - ✔✔Increased weight, drowsy, dizzy, orthostatic hypotension,
tremor, headache, dry mouth, constipation, change in sexual drive, peripheral Edema,
sweating
✔✔Tricyclic mechanism of action - ✔✔Inhibit 5HT2, norepinephrine, dopamine and
reuptake slows. Amino group interferes with ASP - 98 in HSERT. Causing down
regulation of receptors.
✔✔Tricyclic side effects - ✔✔Anticholinergic effects (dry mouth, blurred vision,
constipation, urine retention, impotence). Histamine effects (sedation, increased
weight). Adrenergic alpha receptor (postural hypotension). Direct membrane effects
(decrease seizure threshold and arrhythmias). 5HT2 receptor (increase weight and
decrease anxiety).
✔✔Amitriptyline dosing/Class - ✔✔Start at 25 to 50 mg per day, titrate 25 to 50 mg per
day per week, Max dose is 300 mg per day/TCA