Cellular and Molecular Immunology
by Abul K. Abbas, Andrew H. Lichtman
11th Edition
,Table of contents
1. Properties and Overview of Immune Responses
2. Cells and Tissues of the Immune System
3. Leukocyte Circulation and Migration into Tissues
4. Innate Immunity
5. Antibodies and Antigens
6. Antigen Presentation to T Lymphocytes and the Functions of MHC Molecules
7. Immune Receptors and Signal Transduction
8. Lymphocyte Development and Antigen Receptor Gene Rearrangement
9. Activation of T Lymphocytes
10. Differentiation and Functions of CD4+ Effector T Cells
11. Differentiation and Functions of CD8+ Effector T Cells
12. B Cell Activation and Antibody Production
13. Effector Mechanisms of Humoral Immunity
14. Specialized Immunity at Epithelial Barriers and in Immune Privileged Tissues
15. Immunologic Tolerance and Autoimmunity
16. Immunity to Microbes
17. Transplantation Immunology
18. Immunity to Tumors
19. Hypersensitivity Disorders
20. Allergy
21. Congenital and Acquired Immunodeficiencies
,CHAPTER 1: Properties And Overview Of Immune Responses
MULTIPLE CHOICE QUESTIONS
1. Which Of The Following BEST Defines Immunity?
A) The Ability To Produce Antibodies Against Any Foreign Substance
B) Protection From Infectious Disease Mediated By Cells And Molecules
C) The Nonspecific Destruction Of All Foreign Substances
D) The Process Of Vaccination Against Pathogens
Answer: B
Rationale: Immunity Is Defined As Protection From Infectious Disease. The Cells And
Molecules Responsible For Immunity Constitute The Immune System, And Their Collective
And Coordinated Response To The Introduction Of Foreign Substances Is The Immune
Response. It Encompasses Both Specific And Nonspecific Mechanisms.
2. The Branch Of Biomedical Science That Studies The Immune System Is Called:
A) Microbiology
B) Pathology
C) Immunology
D) Hematology
Answer: C
Rationale: Immunology Is The Branch Of Biomedical Science Concerned With All Aspects
Of The Immune System, Including Its Structure And Function, Disorders Of The Immune
System, Blood Banking, Immunization, And Organ Transplantation.
3. Which Of The Following Is A Characteristic Of Innate Immunity?
A) Memory
B) Specificity
, C) Rapid Response
D) Clonal Expansion
Answer: C
Rationale: Innate Immunity Provides An Immediate, Nonspecific Response To Pathogens.
Unlike Adaptive Immunity, Innate Immunity Does Not Exhibit Memory, Is Not Antigen-
Specific, And Does Not Involve Clonal Expansion Of Lymphocytes.
4. The Two Main Types Of Adaptive Immunity Are:
A) Innate And Acquired Immunity
B) Humoral And Cell-Mediated Immunity
C) Active And Passive Immunity
D) Primary And Secondary Immunity
Answer: B
Rationale: Adaptive Immunity Has Two Main Forms: Humoral Immunity, Mediated By
Antibodies Produced By B Lymphocytes, And Cell-Mediated Immunity, Mediated By T
Lymphocytes. Both Forms Are Antigen-Specific.
5. Which Cells Are Primarily Responsible For Humoral Immunity?
A) T Lymphocytes
B) Natural Killer Cells
C) B Lymphocytes
D) Macrophages
Answer: C
Rationale: Humoral Immunity Is Mediated By B Lymphocytes And Their Secreted
Products, Antibodies (Immunoglobulins). B Cells Differentiate Into Plasma Cells That
Secrete Antibodies Capable Of Neutralizing Pathogens And Toxins.