2026/2027 COMPLETE QUESTIONS WITH
VERIFIED CORRECT ANSWERS || 100%
GUARANTEED PASS <NEWEST VERSION>
This class of antidepressants binds to presynaptic SERT and inhibits them from
reuptake of serotonin to increase levels in the synaptic cleft to bind with
postsysnaptic 5HT2 receptors - ANSWER SSRIs
First line therapy for MDD due to milder side effect profiles - ANSWER SSRIs
Six Common SSRIs - ANSWER citalopram, escitalopram, fluoxetine,
fluvoxamine, sertraline, paroxetine
Onset of therapeutic benefit from SSRIs - ANSWER 4-6 weeks
In addition to MDD, SSRIs also treat - ANSWER Chronic Anxiety, PTSD, OCD,
and eating disorders (bulimia)
Five Common side effects of SSRIs include - ANSWER Anxiety, insomnia, GI
distress, sexual dysfunction (ED), SIADH
Serotonin regulates - ANSWER Mood, emotion, feeding, and reproductive
behavior
Severe side effect of SSRIs in children/adolescents under age 25 years old -
ANSWER suicidal ideation
,Life threatening adverse effect of SSRIs, especially when used in combination
with other serotonergic drugs (SNRIs, TCAs, MAOIs, etc.) - ANSWER Serotonin
Syndrome
Excess accumulation of serotonin resulting in overstimulation of the nervous
system - ANSWER Serotonin Syndrome
Seven symptoms of Serotonin Syndrome - ANSWER Flushing, hyperthermia,
agitation, muscle rigidity, seizure, coma, HYPERreflexia
The treatment for serotonin syndrome - ANSWER Cyproheptadine (5-HT2
receptor antagonist)
Cyproheptadine treats serotonin syndrome by - ANSWER blocking 5-HT2
receptors (serotonin antagonist)
When a person or animal confronts actual (or perceived) danger situations, what
neurochemical and hormonal reactions start to occur? - ANSWER nonessential
physiological processes shut down (i.e. digestion & reproduction), energy is
channeled into a host of functions preparing for rapid action.
Stressful events are perceived at the __________, processed at the _______,
which then activates lower brain areas & puts the limbic system on alert -
ANSWER cortex, amygdala
when there is imminent danger, a burst of excitation originates from the locus
coeruleus which releases _____________, which results in instantaneous
hypervigilance. - ANSWER norepinephrine
, what is responsible for the release of stress hormones? - ANSWER limbic system
and hypothalamus by activating the SNS, HTA, or HPA
_________ ions act as a brake and dampen the limbic alert - ANSWER chloride
________ enhance the flow of negative (chloride) ions which results in
widespread calming in may areas of the brain - ANSWER benzodiazepines
excitability in the locus coerulues is also mediated by _______ - ANSWER
serotonin
in the Locus Coeruleus, serotonin is ____________. - ANSWER inhibitory
A decrease in serotonin may impact the locus coeruleus by making it more
disinhibited and more sensitive to ___________. - ANSWER activation
Acquired fears appear to be mediated primarily by the ___________. - ANSWER
amygdala
After very frightening events, the amygdala ________ certain stimulus events of
the experience. These memories are highly resistant to extinction. - ANSWER
encodes
There is speculation that _______ many play a role in inhibiting cellular reactivity
in the amygdala - ANSWER serotonin
What are four medication options for treating GAD? - ANSWER
benzodiazepines, atypical antianxiety (buspirone), SNRIs and SSRIs, andn
gabapentin
, Benzodiazepines can be used to treat severe cases of GAD, but should not be used
if the patient is at risk for ___________ - ANSWER dependence/substance abuse
_______ reduces worry and rumination seen in GAD, but it is not addictive -
ANSWER Buspirone
This antiseizure medication is primarily used to treat anxiety in bipolar disorder -
ANSWER gabapentin
Specific phobias are generally not treated with __________________. - ANSWER
psychotropic medications
what is effective at reducing anxiety surrounding public speaking? - ANSWER
beta-blockers
Pervasive forms social anxiety (and avoidant personality disorder) may be treated
with what three medications? - ANSWER SSRIs, SNRIs, or MAOIs
____________ is the anxiety disorder for which medication treatment plays its
most important role - ANSWER panic disorder
What three medication classes generally treat panic? - ANSWER benzodiazepines,
antidepressants, and MAO inhibitors
______ of patients have return of panic symptoms if medication is stopped -
ANSWER 70%