: ADVANCED PHARMACOLOGY ||GRADED A+ ||
A patient is prescribed ondansetron 30 minutes before initiation of chemotherapy. The patient
reports that the ondansetron did not work as well as it had previously. What action will the
prescriber take?
Accurate Answer : Prescribe dexamethasone to be given with the ondansetron
A patient receives ondansetron and dexamethasone for chemotherapy-induced nausea and
vomiting (CINV). The patient states that the drugs provide relief during and immediately after
chemotherapy, but that significant nausea and vomiting occur several days after each
chemotherapy treatment. What action will the prescriber take to address this outcome?
Accurate Answer : Suggest adding aprepitant to the medication regimen.
A patient who experiences motion sickness plans to go on a cruise. The prescriber orders
transdermal scopolamine [transderm scop]. The patient asks why an oral agent is not ordered.
What response will the provider give to explain the benefit of a transdermal preparation?
Accurate Answer : This form has less anticholinergic effects than the oral form.
A patient plans to perform missionary work in a region with poor drinking water. The provider
gives the patient a prescription for ciprofloxacin to take on the trip. What instructions will the
prescriber discuss with this patient?
Accurate Answer :
Use the drug if symptoms develop and are severe or do not improve in a few days.
,A patient reports a 6-month history of daily episodes of recurrent, crampy abdominal pain
followed by diarrhea that usually relieves the pain. The patient undergoes a colonoscopy, for
which the findings are normal. What will the provider discuss with the patient?
Accurate Answer :
Keeping a food, stress, and symptom diary
A provider discusses the use of immunosuppressants for the treatment of inflammatory bowel
disease (IBD) with a patient. Which statement by the patient indicates understanding of the
teaching?
Accurate Answer :
Cyclosporine can be used to induce remission of IBD>
A patient with Crohn disease will receive an initial infusion of infliximab. The prescriber explains
how this drug works to treat this disease. Which statement by the patient indicates a need for
further teaching?
Accurate Answer : This drug sometimes provides a complete cure of inflammatory bowel
disease.
The parent of a child with cerebral palsy reports that the child has pebble-like stools most of the
time and seems uncomfortable if several days have passed between stools. The nurse will
suggest that the parent discuss which medication with the child's provider?
Accurate Answer : Polyethylene glycol
,A patient has been taking psyllium two to three times daily for several days but has not passed a
stool. What initial action will the prescriber take when the patient reports abdominal pain?
Accurate Answer : Palpate the patient's abdomen and auscultate for bowel sounds.
Which new diagnosis would prompt the provider to discontinue a PRN order for magnesium
hydroxide?
Accurate Answer : Renal failure
An older adult patient takes an opioid analgesic right after a hip ORIF. Which medication will the
provoider prescribe to prevent constipation?
Accurate Answer : Docusate sodium.
A provider has a routine order for sodium phosphate as a bowel cleanser before a patient's
colonoscopy. The lab report shows that the patient's creatinine clearance and blood urea
nitrogen are both elevated. What will the provider do in response to these lab results?
Accurate Answer : Prescribe polyethylene glycol and electrolytes (PEG-ELS) instead.
A patient reports taking an oral bisacodyl laxative for several years. What instructions will the
provider give the patient to guide the discontinuation of the laxative?
Accurate Answer : Stop taking the laxative immediately and expect no stool for several days.
A patient with a history of chronic alcohol use has been admitted to the unit with a diagnosis of
cirrhosis. Admission laboratory reports show that the patient's ammonia level is elevated at 218
ug/dL. What medication will the provider prescribe to address the lab result?
Accurate Answer : Lactulose
, A patient who has been taking Senna for several days notes that their urine is yellowish brown.
What response will the prescriber provide when the patient expresses concern about this
change?
Accurate Answer : It is an expected, harmless effect of Senna.
When ordering Castor Oil for a patient, what guidance will the provider share with the nurse?
Accurate Answer : Chill the medication and mix it with fruit juice
A patient diagnosed with renal disease is scheduled for a colonoscopy. What drug will the
provider prescribe for administration before the procedure?
Accurate Answer : Polyethylene glycol plus electrolytes (PEG-ELS)
A patient with lower abdominal pain and nausea is admitted to the hospital. The patient's
abdomen is distended and firm with hypoactive bowel sounds. The patient reports of not having
a bowel movement for 3 days. What initial action will the provider take?
Accurate Answer : Order diagnostic tests
A patient takes nonsteroidal anti-inflammatory drugs (NSAIDS) for arthritis. What can the
provider prescribe to prevent ulcers?
Accurate Answer : Proton pump inhibitors
A patient with a history of peptic ulcer disease takes ranitidine and sucralfate. The patient
reports that discomfort is usually controlled but that symptoms occasionally flare up. What
action will the provider take tot address the patient's concern?
Accurate Answer : Discuss testing for H. pylori and an antibiotic