APHA IMMUNIZATION EXAM 4
COMPREHENSIVE VACCINATION PRACTICE
AND IMMUNIZATION STUDY GUIDE 2026
◉ HZV, MMR, rabies, typhoid, varicella, or yellow fever vaccine
should not be administered to a patient with a history of anaphylaxis
to:
Answer: Gelatin
◉ Alan is a 47-year-old man who has no documentation of a primary
series of tetanus-containing vaccine. Which of the following would
be an appropriate primary series for Alan?
Answer: 1) Tdap
2) Td 4 weeks later
3) Td 6-12 months later
Td booster every 10 years after 3rd dose
◉ Candidate for PPSV23?
Answer: All adults 65+ years
,Immunocompromised (alcoholism, chronic liver; heart; lung disease,
diabetics, cochlear implants, CSF leak) patients ages 19-64
Children with asthma only if theyre treated with high dose
corticosteriods
◉ Name the vaccine-preventable disease that may be contracted by
unimmunized children from adults serving as reservoirs for the
disease, which causes a paroxysmal cough and potentially can result
in pneumonia, seizures, encephalopathy, hypoxia, and death.
Answer: Pertussis
◉ Which of the following vaccines may be administered to males
and females aged 9 through 26 years to reduce the likelihood of
acquiring genital warts?
Answer: 9vHPV
◉ Which of the following key questions is important to ask a patient
before administering IIV?
Answer: Are you sick today?
*Mild illness is okay, but moderate to severe acute illness need to be
resolved before getting vaccine.
,◉ Live attenuated vaccines..
Answer: produced by weakening the virus or bacteria to reduce the
likelihood that it can cause disease
end to produce more persistent, longer-lasting immunity than
inactivated vaccines
must replicate in order for the body to produce an immune response
could cause disease in immunocompromised patients
Circulating antibodies may interfere with a live attenuated vaccine's
ability to replicate.
◉ Inactivated vaccines...
Answer: are produced by killing the virus/bacteria
includes polysaccharide vaccines (conjugated [protein altered] or
unconjugated), toxoids, or cellular vaccines
◉ Which type of vaccine involves stimulation of B cells without the
assistance of T helper cells?
Answer: A pure polysaccharide
, *not recommended for children <2 because of their immature
immune system
◉ Conjugated vaccines..
Answer: provide longer lasting protection
the immune response that changes to a T cell mediated response
allows children <2 to form an immune response
◉ T/F
Both live attenuated vaccines and recombinant vaccines mimic
natural infection and involve T cells in the immune response.
Answer: True
◉ The incubation period for influenza can range from:
Answer: 1-4 days
◉ What is the time interval for which the development of Guillain-
Barre syndrome following influenza vaccination would result in a
precaution for future influenza vaccines?
Answer: 6 weeks
COMPREHENSIVE VACCINATION PRACTICE
AND IMMUNIZATION STUDY GUIDE 2026
◉ HZV, MMR, rabies, typhoid, varicella, or yellow fever vaccine
should not be administered to a patient with a history of anaphylaxis
to:
Answer: Gelatin
◉ Alan is a 47-year-old man who has no documentation of a primary
series of tetanus-containing vaccine. Which of the following would
be an appropriate primary series for Alan?
Answer: 1) Tdap
2) Td 4 weeks later
3) Td 6-12 months later
Td booster every 10 years after 3rd dose
◉ Candidate for PPSV23?
Answer: All adults 65+ years
,Immunocompromised (alcoholism, chronic liver; heart; lung disease,
diabetics, cochlear implants, CSF leak) patients ages 19-64
Children with asthma only if theyre treated with high dose
corticosteriods
◉ Name the vaccine-preventable disease that may be contracted by
unimmunized children from adults serving as reservoirs for the
disease, which causes a paroxysmal cough and potentially can result
in pneumonia, seizures, encephalopathy, hypoxia, and death.
Answer: Pertussis
◉ Which of the following vaccines may be administered to males
and females aged 9 through 26 years to reduce the likelihood of
acquiring genital warts?
Answer: 9vHPV
◉ Which of the following key questions is important to ask a patient
before administering IIV?
Answer: Are you sick today?
*Mild illness is okay, but moderate to severe acute illness need to be
resolved before getting vaccine.
,◉ Live attenuated vaccines..
Answer: produced by weakening the virus or bacteria to reduce the
likelihood that it can cause disease
end to produce more persistent, longer-lasting immunity than
inactivated vaccines
must replicate in order for the body to produce an immune response
could cause disease in immunocompromised patients
Circulating antibodies may interfere with a live attenuated vaccine's
ability to replicate.
◉ Inactivated vaccines...
Answer: are produced by killing the virus/bacteria
includes polysaccharide vaccines (conjugated [protein altered] or
unconjugated), toxoids, or cellular vaccines
◉ Which type of vaccine involves stimulation of B cells without the
assistance of T helper cells?
Answer: A pure polysaccharide
, *not recommended for children <2 because of their immature
immune system
◉ Conjugated vaccines..
Answer: provide longer lasting protection
the immune response that changes to a T cell mediated response
allows children <2 to form an immune response
◉ T/F
Both live attenuated vaccines and recombinant vaccines mimic
natural infection and involve T cells in the immune response.
Answer: True
◉ The incubation period for influenza can range from:
Answer: 1-4 days
◉ What is the time interval for which the development of Guillain-
Barre syndrome following influenza vaccination would result in a
precaution for future influenza vaccines?
Answer: 6 weeks
