APHA IMMUNIZATION EXAM 4 HIGH-YIELD
VACCINE STORAGE, ADMINISTRATION, AND
CONTRAINDICATIONS SUMMARY 2026
◉ LAIV4 is the abbreviation for:
Answer: Live Attenuated Influenza Vaccine
◉ RV1, RV5 is the abbreviation for:
Answer: Rotavirus
◉ VAR is the abbreviation for:
Answer: Varicella
◉ MMR is the abbreviation for:
Answer: Measles, mumps, rubella
◉ MMRV is the abbreviation for:
Answer: Measles, mumps, rubella, varicella
◉ Can inactivated vaccines replicate?
Answer: No. It does not cause disease.
,◉ What are two broad categories that vaccines are classified as?
Answer: 1. Live attenuated vaccines
2. Inactivated vaccines
◉ Cellular Vaccines
Answer: 1. Inactivated Vaccines
2. Whole viruses or bacteria
3. Known as Subunits (fractions)
4. DTP/DTaP
◉ Toxoid Vaccines
Answer: 1. Inactivated Vaccine
2. Subunit (fractions)
3. Inactive or biological toxin
4. Tetanus toxoid
◉ Recombinant Vaccine
Answer: 1. Produced by genetic engineering
2. May contain no actual virus or a modified strain of a virus
3. HepB, HPV, RZV, RIV4
,◉ What clinical factors need to be considered before administering a
lie attenuated vaccine?
Answer: 1. Patients who currently are immunocompromised
2. Live attenuated vaccines administered in the previous 28 days.
◉ T/F: MMR is a live attenuated vaccine.
Answer: True
◉ Which of the following vaccines listed is a live attenuated vaccine?
a.) Hep B
b.) Hep A
c.) RZV
d.) VAR
Answer: d.) VAR
◉ Pneumococcal polysaccharide vaccine (PPSV23) is best
categorized as what type of vaccine?
Answer: Inactivated Polysaccharide Vaccine
◉ Which of the following is true regarding the use of mRNA in
vaccine technology?
a.) mRNA is extremely stable in a host's body.
, b.) mRNA is the genetic blueprint that tells your body how to make a
particular protein subunit of a virus which, after being produced,
will elicit an immune response.
c.) mRNA vaccine technology requires replication similar to a live
attenuated vaccine.
d.) mRNA vaccine technology elicits its immune response and
protects the host by altering the host's DNA.
Answer: b.) mRNA is the genetic blueprint that tells your body how
to make a particular protein subunit of a virus which, after being
produced, will elicit an immune response.
◉ Which vaccine technol is an ingredient added typically to
inactivated vaccines to boost its immune response by targeting
pathogen recognition receptors that are expressed on dendritic cells
to trigger a pro-inflammatory response? Though this technology
creates a more robust immune response, it can also increase local
site reactions and systemic reactions, such as fevers, chills, and body
aches.
Answer: Adjuvants (manufactured to produce a more robust
immune response to the vaccine)
◉ When administering measles, mumps, rubella (MMR) and
pneumococcal conjugate vaccine (PCV13) to a patient at their 15-
month appointment, what must be considered regarding vaccine
spacing?
VACCINE STORAGE, ADMINISTRATION, AND
CONTRAINDICATIONS SUMMARY 2026
◉ LAIV4 is the abbreviation for:
Answer: Live Attenuated Influenza Vaccine
◉ RV1, RV5 is the abbreviation for:
Answer: Rotavirus
◉ VAR is the abbreviation for:
Answer: Varicella
◉ MMR is the abbreviation for:
Answer: Measles, mumps, rubella
◉ MMRV is the abbreviation for:
Answer: Measles, mumps, rubella, varicella
◉ Can inactivated vaccines replicate?
Answer: No. It does not cause disease.
,◉ What are two broad categories that vaccines are classified as?
Answer: 1. Live attenuated vaccines
2. Inactivated vaccines
◉ Cellular Vaccines
Answer: 1. Inactivated Vaccines
2. Whole viruses or bacteria
3. Known as Subunits (fractions)
4. DTP/DTaP
◉ Toxoid Vaccines
Answer: 1. Inactivated Vaccine
2. Subunit (fractions)
3. Inactive or biological toxin
4. Tetanus toxoid
◉ Recombinant Vaccine
Answer: 1. Produced by genetic engineering
2. May contain no actual virus or a modified strain of a virus
3. HepB, HPV, RZV, RIV4
,◉ What clinical factors need to be considered before administering a
lie attenuated vaccine?
Answer: 1. Patients who currently are immunocompromised
2. Live attenuated vaccines administered in the previous 28 days.
◉ T/F: MMR is a live attenuated vaccine.
Answer: True
◉ Which of the following vaccines listed is a live attenuated vaccine?
a.) Hep B
b.) Hep A
c.) RZV
d.) VAR
Answer: d.) VAR
◉ Pneumococcal polysaccharide vaccine (PPSV23) is best
categorized as what type of vaccine?
Answer: Inactivated Polysaccharide Vaccine
◉ Which of the following is true regarding the use of mRNA in
vaccine technology?
a.) mRNA is extremely stable in a host's body.
, b.) mRNA is the genetic blueprint that tells your body how to make a
particular protein subunit of a virus which, after being produced,
will elicit an immune response.
c.) mRNA vaccine technology requires replication similar to a live
attenuated vaccine.
d.) mRNA vaccine technology elicits its immune response and
protects the host by altering the host's DNA.
Answer: b.) mRNA is the genetic blueprint that tells your body how
to make a particular protein subunit of a virus which, after being
produced, will elicit an immune response.
◉ Which vaccine technol is an ingredient added typically to
inactivated vaccines to boost its immune response by targeting
pathogen recognition receptors that are expressed on dendritic cells
to trigger a pro-inflammatory response? Though this technology
creates a more robust immune response, it can also increase local
site reactions and systemic reactions, such as fevers, chills, and body
aches.
Answer: Adjuvants (manufactured to produce a more robust
immune response to the vaccine)
◉ When administering measles, mumps, rubella (MMR) and
pneumococcal conjugate vaccine (PCV13) to a patient at their 15-
month appointment, what must be considered regarding vaccine
spacing?
