BMB 402 Exam 3 || 100% Accurate Solutions.
Uric acid doesn't look like most acids in biochemistry. Which protons are acidic? correct answers
the protons on the carbonyl groups
Ribonucleotide reductase can be separated into two dimers, an a2 dimer and a b2 dimer. Would
you expect either of these two dimers independently to have catalytic activity? Why or why not?
correct answers No, the two subunits must work together to have catalytic activity
IMP synthesis from ribose-5-phoshpate requires ____ ATP hydrolyses correct answers 6
Addition of pyrophosphate to which of the following occurs during the first step of purine
biosynthesis? correct answers ribose-5-phosphate
____ is released as adenylosuccinate lyase catalyzes the conversion of adnelyosuccinate to AMP
correct answers fumarate
Which of the following is not required for purine biosynthesis?
I. aspartate
II. glycine
III. glutamine
IV. 10-formyl tetrahydrofolate correct answers all of the above are required
Which of the following amino acids is a source of both carbon and nitrogen for IMP? correct
answers Gly
The precursor to AMP and GMP is ____ correct answers IMP
The conversion of IMP to AMP requires ____; the conversion of IMP to GMP requires ____
correct answers Asp
Gln
Which of the following correctly describes the general synthesis of purine nucelotides? correct
answers The basic ring structure, inosine, is synthesized stepwise on PRPP
The energy for the conversion of IMP to GMP is supplied by ___ correct answers ATP
Which of the following steps in purine biosynthesis are regulated by feedback inhibition by ADP
and GDP?
I. ribose-5-phosphate --> PRPP
II. PRPP --> 5-phosphoribosame
III. glycine ribonucleotide --> formylglycinamide ribonucleotide
IV. FAICAR --> IMP
V. IMP --> adenylosuccinate correct answers I and II
Uric acid doesn't look like most acids in biochemistry. Which protons are acidic? correct answers
the protons on the carbonyl groups
Ribonucleotide reductase can be separated into two dimers, an a2 dimer and a b2 dimer. Would
you expect either of these two dimers independently to have catalytic activity? Why or why not?
correct answers No, the two subunits must work together to have catalytic activity
IMP synthesis from ribose-5-phoshpate requires ____ ATP hydrolyses correct answers 6
Addition of pyrophosphate to which of the following occurs during the first step of purine
biosynthesis? correct answers ribose-5-phosphate
____ is released as adenylosuccinate lyase catalyzes the conversion of adnelyosuccinate to AMP
correct answers fumarate
Which of the following is not required for purine biosynthesis?
I. aspartate
II. glycine
III. glutamine
IV. 10-formyl tetrahydrofolate correct answers all of the above are required
Which of the following amino acids is a source of both carbon and nitrogen for IMP? correct
answers Gly
The precursor to AMP and GMP is ____ correct answers IMP
The conversion of IMP to AMP requires ____; the conversion of IMP to GMP requires ____
correct answers Asp
Gln
Which of the following correctly describes the general synthesis of purine nucelotides? correct
answers The basic ring structure, inosine, is synthesized stepwise on PRPP
The energy for the conversion of IMP to GMP is supplied by ___ correct answers ATP
Which of the following steps in purine biosynthesis are regulated by feedback inhibition by ADP
and GDP?
I. ribose-5-phosphate --> PRPP
II. PRPP --> 5-phosphoribosame
III. glycine ribonucleotide --> formylglycinamide ribonucleotide
IV. FAICAR --> IMP
V. IMP --> adenylosuccinate correct answers I and II
