BSN 315 Week 15 ACTUAL UPDATED QUESTIONS AND CORRECT ANSWERS
Biologic Response Modifier Therapy Colony-stimulating factors
Question 1 of 15 Colony-stimulating factors stimulate production of bone marrow stem cells. They
Which biologic response modifier is expected to are used to shorten recovery time after bone marrow transplantation and allow
stimulate the production of bone marrow cells and to for higher doses of chemotherapy to be given to minimize adverse effects.
shorten the recovery time after bone marrow Interferons
transplantation?
Colony-stimulating factors
Interferons
Interleukin (IL)-2 agonists
Keratinocyte growth factors (KGFs)
Question 2 of 15 Inhibit division and replication of tumor cells
Which phrases are accurate descriptions of the role of Produced in the body by activated T cells and other cells during viral replication
interferons? Assist cells by producing enzymes that block viral replication and stop viral entry
Select all that apply. into healthy cells
Inhibit division and replication of tumor cells
Stimulate DNA and protein production in cancer cells
Inhibit the activity of macrophages, neutrophils, and
natural killer cells
Produced in the body by activated T cells and other cells
during viral replication
Assist cells by producing enzymes that block viral
replication and stop viral entry into healthy cells
, Question 3 of 15 Colony-stimulating factors
Which biologic response modifiers (BRMs) are proteins Interferons
that are made by cells in the body's immune system? Interleukins
Select all that apply. Keratinocyte growth factors
Colony-stimulating factors
Interferons
Interleukins
Keratinocyte growth factors
Monoclonal antibodies
Question 4 of 15 IFN-alfa-2a
Which IFN-alfa products are used for the management of IFN-alfa-2b
chronic hepatitis C? Peginterferon alfa-2a
Select all that apply. Peginterferon alfa-2b
IFN-alfa-2a
IFN-alfa-2b
Peginterferon alfa-2a
Peginterferon alfa-2b
IFN-alfa-n3
Question 5 of 15 Multiple sclerosis
Which disease state would interferon-β products be used IFN-β products are used to manage multiple sclerosis. They bind selectively to β-
to manage? cell receptor sites to augment suppressor T-cell function, decrease production of
Chronic granulomatous disease proinflammatory cytokines, and initiate immune system reactions to reduce
Chronic hepatitis C antigen presentation.
Multiple sclerosis
Osteopetrosis
Question 6 of 15 Peginterferon alfa-2b
Which IFN-alfa product is expected to have the longest Because it is pegylated, this interferon product is larger in size and is expected to
elimination half-life? have a delayed absorption, prolonged half-life, and decreased clearance rate.
IFN-alfa-2a
IFN-alfa-2b
IFN-alfa-n3
Peginterferon alfa-2b
Question 7 of 15 Palifermin
Which drug is administered to promote proliferation, Palifermin is a keratinocyte growth factor (KGF) that acts on KGF receptors to
differentiation, and migration of epithelial cells? promote proliferation, differentiation, and migration of epithelial cells.
Aldesleukin
Filgrastim
Palifermin
Sargramostim
Question 8 of 15 The drug is distributed through the extracellular space.
Which statement regarding the pharmacokinetic profile Aldesleukin is distributed through the extracellular space, with about 70% of each
of aldesleukin is accurate? dose being preferentially taken up by the liver, lungs, and kidneys.
Metabolites are excreted in the feces.
Aldesleukin has an absolute bioavailability of 75%.
The drug is distributed through the extracellular space.
Hepatic enzymes convert aldesleukin into inactive
metabolites.
Biologic Response Modifier Therapy Colony-stimulating factors
Question 1 of 15 Colony-stimulating factors stimulate production of bone marrow stem cells. They
Which biologic response modifier is expected to are used to shorten recovery time after bone marrow transplantation and allow
stimulate the production of bone marrow cells and to for higher doses of chemotherapy to be given to minimize adverse effects.
shorten the recovery time after bone marrow Interferons
transplantation?
Colony-stimulating factors
Interferons
Interleukin (IL)-2 agonists
Keratinocyte growth factors (KGFs)
Question 2 of 15 Inhibit division and replication of tumor cells
Which phrases are accurate descriptions of the role of Produced in the body by activated T cells and other cells during viral replication
interferons? Assist cells by producing enzymes that block viral replication and stop viral entry
Select all that apply. into healthy cells
Inhibit division and replication of tumor cells
Stimulate DNA and protein production in cancer cells
Inhibit the activity of macrophages, neutrophils, and
natural killer cells
Produced in the body by activated T cells and other cells
during viral replication
Assist cells by producing enzymes that block viral
replication and stop viral entry into healthy cells
, Question 3 of 15 Colony-stimulating factors
Which biologic response modifiers (BRMs) are proteins Interferons
that are made by cells in the body's immune system? Interleukins
Select all that apply. Keratinocyte growth factors
Colony-stimulating factors
Interferons
Interleukins
Keratinocyte growth factors
Monoclonal antibodies
Question 4 of 15 IFN-alfa-2a
Which IFN-alfa products are used for the management of IFN-alfa-2b
chronic hepatitis C? Peginterferon alfa-2a
Select all that apply. Peginterferon alfa-2b
IFN-alfa-2a
IFN-alfa-2b
Peginterferon alfa-2a
Peginterferon alfa-2b
IFN-alfa-n3
Question 5 of 15 Multiple sclerosis
Which disease state would interferon-β products be used IFN-β products are used to manage multiple sclerosis. They bind selectively to β-
to manage? cell receptor sites to augment suppressor T-cell function, decrease production of
Chronic granulomatous disease proinflammatory cytokines, and initiate immune system reactions to reduce
Chronic hepatitis C antigen presentation.
Multiple sclerosis
Osteopetrosis
Question 6 of 15 Peginterferon alfa-2b
Which IFN-alfa product is expected to have the longest Because it is pegylated, this interferon product is larger in size and is expected to
elimination half-life? have a delayed absorption, prolonged half-life, and decreased clearance rate.
IFN-alfa-2a
IFN-alfa-2b
IFN-alfa-n3
Peginterferon alfa-2b
Question 7 of 15 Palifermin
Which drug is administered to promote proliferation, Palifermin is a keratinocyte growth factor (KGF) that acts on KGF receptors to
differentiation, and migration of epithelial cells? promote proliferation, differentiation, and migration of epithelial cells.
Aldesleukin
Filgrastim
Palifermin
Sargramostim
Question 8 of 15 The drug is distributed through the extracellular space.
Which statement regarding the pharmacokinetic profile Aldesleukin is distributed through the extracellular space, with about 70% of each
of aldesleukin is accurate? dose being preferentially taken up by the liver, lungs, and kidneys.
Metabolites are excreted in the feces.
Aldesleukin has an absolute bioavailability of 75%.
The drug is distributed through the extracellular space.
Hepatic enzymes convert aldesleukin into inactive
metabolites.
