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BIOS 251 Anatomy & Physiology I with Lab – September Cumulative Final Exam (Questions & Answers with Rationales)

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This document is a comprehensive cumulative final exam for BIOS 251 (Anatomy & Physiology I with Lab), featuring 150 multiple-choice questions with correct answers and detailed rationales. Topics include: orientation to the human body (heart in thoracic cavity, not abdominopelvic; homeostasis definition; proximal vs distal; parietal peritoneum lines abdominopelvic cavity; physiology vs anatomy; structural organization from chemical to organism; posterior vs anterior; midsagittal plane divides equal left/right; transverse plane separates superior/inferior; pleural cavity contains lungs; dorsal cavity houses brain and spinal cord; negative feedback example – temperature regulation; hypogastric region; visceral pleura covers lungs; prone position), chemistry of life and cell biology (most acidic pH 2.5; four most common elements O, C, H, N; covalent bond shares electrons; water polarity as solvent; mitochondria produce ATP; plasma membrane phospholipids/proteins; osmosis moves water without energy; hypertonic solution causes crenation; lysosomes contain digestive enzymes; ribosomes synthesize proteins; metaphase aligns chromosomes; sodium-potassium pump moves 3 Na⁺ out, 2 K⁺ in (active transport); microfilaments (actin) involved in muscle contraction; nucleolus assembles ribosomes; tRNA carries amino acids; facilitated diffusion uses carrier/channel proteins; smooth ER synthesizes lipids and detoxifies; isotonic solution has same solute concentration as blood plasma; S phase duplicates genetic material; apoptosis is programmed cell death), histology (epithelial tissue covers surfaces/lines cavities; simple squamous in alveoli; pseudostratified columnar appears stratified; endocrine glands secrete into blood; chondrocytes produce extracellular matrix; areolar connective tissue has loose arrangement with fibroblasts and all three fiber types; hyaline cartilage in epiphyseal plates/nose; muscle tissue specialized for contraction; cardiac muscle has intercalated discs; osteoclasts resorb bone; dense regular CT in tendons/ligaments; contraction is NOT a function of connective tissue; hyaline cartilage most abundant; transitional epithelium in urinary bladder; reticular fibers), integumentary system (stratum corneum outermost; melanocytes produce melanin; dermis is dense irregular CT; sebaceous glands secrete sebum; vitamin D synthesized in skin upon UV exposure; third-degree burn involves epidermis, dermis, and subcutaneous tissue; stratum lucidum only in thick skin; melanin primary skin pigment; functions include protection, thermoregulation, sensation; hypodermis composed of adipose tissue; Merkel cells for touch sensation; eccrine sweat glands most abundant on palms, soles, forehead; hair follicle anchors hair; arrector pili causes goosebumps; acne from excess sebum and blocked ducts), skeletal system (206 bones in adult; diaphysis is shaft of long bone; osteocytes maintain bone matrix; osteon is structural unit of compact bone; sternum is axial skeleton; foramen magnum in occipital bone; diarthrosis freely movable; patella is sesamoid bone; PTH increases blood calcium by stimulating osteoclasts; epiphyseal plate for longitudinal bone growth; mastoid process in temporal bone; atlas is C1; fontanelle is infant “soft spot”; acetabulum on ilium/hip bone; hematopoiesis is skeletal function; olecranon process on ulna; comminuted fracture has many fragments; 7 cervical vertebrae; intervertebral discs composed of fibrocartilage; femur articulates with acetabulum), muscular system (myosin in thick filaments; sarcomere is functional unit; acetylcholine at neuromuscular junction; sliding filament theory – sarcomeres shorten as actin slides over myosin; Type I slow oxidative fibers are fatigue-resistant; origin is fixed attachment; biceps brachii prime mover for elbow flexion; rigor mortis from lack of ATP preventing myosin release; sarcoplasmic reticulum stores calcium; diaphragm is inspiration muscle; all-or-none principle – single muscle fiber contracts maximally or not at all; tetanus is sustained contraction from rapid stimuli; triceps extends elbow, biceps flexes (antagonist pair); creatine phosphate first energy source for short intense exercise; quadriceps extend knee; brachialis synergist to biceps; asynchronous motor unit recruitment maintains muscle tone; cardiac muscle is uninucleated (not multinucleated); endomysium surrounds individual muscle fiber; Ca²⁺ necessary for cross-bridge formation), nervous system (neuron is basic functional unit; dendrites receive incoming signals; oligodendrocytes form myelin sheath in CNS; resting membrane potential –70 mV; depolarization from Na⁺ influx; repolarization from K⁺ efflux; saltatory conduction in myelinated axons at nodes of Ranvier; synapse is space between two neurons; GABA is inhibitory neurotransmitter; ANS regulates involuntary functions; sympathetic division mediates fight-or-flight; cerebrum has 4 lobes (frontal, parietal, temporal, occipital); frontal lobe contains primary motor cortex; corpus callosum connects cerebral hemispheres; hypothalamus regulates temperature, hunger, thirst; astrocytes and tight junctions form blood-brain barrier; optic nerve (II) responsible for vision; pia mater directly covers brain; motor neuron carries signal to effector; damage to Broca’s area causes inability to produce fluent speech), sensory and lab-based skills (hyaline cartilage has glassy matrix with chondrocytes in lacunae; hematoxylin stains nuclei; pineal gland in diencephalon (epithalamus); stethoscope over brachial artery for BP; normal resting heart rate 60–100 bpm; muscle spindle is receptor in patellar reflex; P200 micropipette measures 150 μL; expiratory reserve volume in spirometry; glucose positive dipstick indicates diabetes mellitus; total magnification 400x with 10x ocular and 40x objective), comprehensive review (pivot joint example – proximal radioulnar joint; damage to ventral root causes loss of motor function; mitochondria abundant in axon terminals; anatomical position – palms facing anterior, thumbs lateral; deltoid prime mover for shoulder abduction; epinephrine released by adrenal medulla; cerebellum function – coordination and balance; ribosomes are non-membranous organelles; low blood calcium triggers PTH release; simple cuboidal epithelium in kidneys for diffusion; smooth muscle lacks striations and is involuntary; medulla oblongata contains cardiac and respiratory centers; Schwann cells produce myelin sheath in PNS; homeostatic imbalance – body unable to regulate internal temperature; dense regular connective tissue – parallel collagen fibers, high tensile strength). Suitable for BIOS 251 cumulative final exam preparation, A&P I students, and nursing/pre-med review.

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Voorbeeld van de inhoud

BIOS 251: ANATOMY & PHYSIOLOGY I
WITH LAB SEPTEMBER ACTUAL
CUMULATIVE FINAL COMPREHENSIVE
FINAL EXAMINATION WITH QUESTIONS
AND ANSWERS WITH RATIONALES




NB: 6 Credits Total, With The Lecture Portion Weighted At ~4 Credits And Lab At 2 Credits


Section 1: Orientation to the Human Body (Questions 1–15)



11. Which organ is NOT found in the abdominopelvic cavity?

o a) Stomach o b) Liver o c) Spleen o d) Heart o Rationale: Heart

is in thoracic cavity (pericardial cavity).
12. Homeostasis is best defined as:

o a) A constant internal environment

o b) Maintenance of a stable internal environment despite external changes o
Rationale: Homeostasis involves dynamic equilibrium, not absolute constancy.
o c) An increase in body temperature during infection o d) The response to external
stimuli
13. The elbow is ______ to the wrist.

,o



o a) Distal o b) Proximal o Rationale: Proximal =
closer to point of attachment; elbow is closer to shoulder
than wrist.
o c) Medial o d) Superficial
14. Which cavity is lined by the parietal peritoneum?

o a) Cranial cavity o b) Thoracic cavity o c) Abdominopelvic cavity o Rationale:
Peritoneum lines abdominopelvic cavity; pleura lines thoracic.
o d) Spinal cavity

15. The study of the function of body parts is called:

o a) Anatomy o b) Physiology o Rationale: Physiology =
function; anatomy = structure.
c) Histology

d) Cytology



1. Which of the following represents the correct order of structural organization from simplest to most
complex?

o a) Organ, tissue, cellular, chemical, system, organism o b) Chemical, cellular, tissue, organ,
system, organism
o Rationale: Chemical level (atoms/molecules) → cellular → tissue → organ → organ system →
organism.
o c) Cellular, chemical, tissue, organ, system, organism

d) Chemical, tissue, cellular, organ, system, organism

2. The heart is ______ to the sternum.

o a) Anterior
o b) Lateral
o c) Posterior

,o

o

o Rationale:
The sternum
is anterior
to the heart;
thus the
heart is
posterior
(dorsal) to
the sternum.
o d) Superior
3. Which plane divides the body into equal left and right halves?

o a) Parasagittal o b) Frontal o c) Transverse o d)
Midsagittal
o Rationale: Midsagittal (median) plane divides into
equal left/right halves; parasagittal divides into
unequal halves.
4. A cut through the transverse plane would produce:

o a) Superior and inferior sections o Rationale:
Transverse (horizontal) plane separates superior from
inferior.
o b) Anterior and posterior sections o c) Left and right
sections o d) Oblique sections only
5. Which body cavity contains the lungs?

o a) Abdominal cavity o b) Pelvic cavity o c) Pleural
cavity
o Rationale: Pleural cavities (part of thoracic cavity)
house the lungs; pericardial cavity houses the heart. o d)
Pericardial cavity

, o



6. The dorsal body cavity houses:

a) Heart and lungs

b) Brain and spinal cord

o Rationale: Dorsal cavity includes cranial cavity (brain) and
vertebral canal (spinal cord).

o c) Digestive organs o d) Kidneys and bladder
7. Which of the following is an example of negative feedback?

o a) Blood clotting o b) Childbirth contractions o c) Regulation of body temperature
o Rationale: Negative feedback reverses a change (e.g., sweating cools body). Childbirth and
clotting are positive feedback.
o d) Ovulation

8. The abdominopelvic region located directly below the umbilical region is the:

o a) Epigastric o b) Hypogastric
(pubic) o Rationale: Umbilical is center;
hypogastric is inferior to it.
o c) Left iliac o d) Right lumbar
9. Which serous membrane directly covers the surface of the lungs?

o a) Parietal pleura o b) Visceral pleura o Rationale:
Visceral pleura adheres to lung tissue; parietal pleura lines
thoracic wall.
o c) Visceral pericardium o d) Parietal peritoneum
10. A person lying face down is in the ______ position.

o a) Supine o b) Prone o Rationale: Prone = face down; supine = face up.
o c) Anatomical

d) Lateral recumbent

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